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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ISG20L2
Full Name:
Interferon-stimulated 20 kDa exonuclease-like 2
Alias:
Type:
Mass (Da):
39154
Number AA:
353
UniProt ID:
Q9H9L3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
L
E
R
R
G
F
L
S
K
K
N
Q
P
P
S
Site 2
S49
S
K
K
N
Q
P
P
S
K
A
P
K
L
H
S
Site 3
S56
S
K
A
P
K
L
H
S
E
P
S
K
K
G
E
Site 4
S59
P
K
L
H
S
E
P
S
K
K
G
E
T
P
T
Site 5
T64
E
P
S
K
K
G
E
T
P
T
V
D
G
T
W
Site 6
T66
S
K
K
G
E
T
P
T
V
D
G
T
W
K
T
Site 7
T73
T
V
D
G
T
W
K
T
P
S
F
P
K
K
K
Site 8
S75
D
G
T
W
K
T
P
S
F
P
K
K
K
T
A
Site 9
T81
P
S
F
P
K
K
K
T
A
A
S
S
N
G
S
Site 10
S84
P
K
K
K
T
A
A
S
S
N
G
S
G
Q
P
Site 11
S88
T
A
A
S
S
N
G
S
G
Q
P
L
D
K
K
Site 12
S99
L
D
K
K
A
A
V
S
W
L
T
P
A
P
S
Site 13
T102
K
A
A
V
S
W
L
T
P
A
P
S
K
K
A
Site 14
S106
S
W
L
T
P
A
P
S
K
K
A
D
S
V
A
Site 15
S111
A
P
S
K
K
A
D
S
V
A
A
K
V
D
L
Site 16
S124
D
L
L
G
E
F
Q
S
A
L
P
K
I
N
S
Site 17
S131
S
A
L
P
K
I
N
S
H
P
T
R
S
Q
K
Site 18
S136
I
N
S
H
P
T
R
S
Q
K
K
S
S
Q
K
Site 19
S140
P
T
R
S
Q
K
K
S
S
Q
K
K
S
S
K
Site 20
S141
T
R
S
Q
K
K
S
S
Q
K
K
S
S
K
K
Site 21
S145
K
K
S
S
Q
K
K
S
S
K
K
N
H
P
Q
Site 22
S146
K
S
S
Q
K
K
S
S
K
K
N
H
P
Q
K
Site 23
S159
Q
K
N
A
P
Q
N
S
T
Q
A
H
S
E
N
Site 24
T160
K
N
A
P
Q
N
S
T
Q
A
H
S
E
N
K
Site 25
S169
A
H
S
E
N
K
C
S
G
A
S
Q
K
L
P
Site 26
T189
I
D
C
E
M
V
G
T
G
P
K
G
H
V
S
Site 27
S202
V
S
S
L
A
R
C
S
I
V
N
Y
N
G
D
Site 28
Y206
A
R
C
S
I
V
N
Y
N
G
D
V
L
Y
D
Site 29
Y212
N
Y
N
G
D
V
L
Y
D
E
Y
I
L
P
P
Site 30
Y225
P
P
C
H
I
V
D
Y
R
T
R
W
S
G
I
Site 31
T241
K
Q
H
M
V
N
A
T
P
F
K
I
A
R
G
Site 32
Y273
N
D
F
K
A
L
Q
Y
F
H
P
K
S
L
T
Site 33
S278
L
Q
Y
F
H
P
K
S
L
T
R
D
T
S
H
Site 34
T283
P
K
S
L
T
R
D
T
S
H
I
P
P
L
N
Site 35
S284
K
S
L
T
R
D
T
S
H
I
P
P
L
N
R
Site 36
S320
R
D
I
Q
V
G
K
S
G
H
S
S
V
E
D
Site 37
S324
V
G
K
S
G
H
S
S
V
E
D
A
Q
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation