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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC40
Full Name:
Leucine-rich repeat-containing protein 40
Alias:
FLJ20331; Leucine rich repeat containing 40; LRC40
Type:
Mass (Da):
68250
Number AA:
602
UniProt ID:
Q9H9A6
International Prot ID:
IPI00152998
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
A
G
G
R
D
C
G
T
S
V
P
Q
G
L
L
Site 2
S26
G
G
R
D
C
G
T
S
V
P
Q
G
L
L
K
Site 3
S38
L
L
K
A
A
R
K
S
G
Q
L
N
L
S
G
Site 4
S44
K
S
G
Q
L
N
L
S
G
R
N
L
S
E
V
Site 5
S49
N
L
S
G
R
N
L
S
E
V
P
Q
C
V
W
Site 6
S71
E
E
A
N
Q
N
L
S
F
G
A
T
E
R
W
Site 7
S96
I
S
N
N
K
L
Q
S
L
T
D
D
L
R
L
Site 8
T98
N
N
K
L
Q
S
L
T
D
D
L
R
L
L
P
Site 9
T118
D
I
H
D
N
Q
L
T
S
L
P
S
A
I
R
Site 10
S119
I
H
D
N
Q
L
T
S
L
P
S
A
I
R
E
Site 11
S122
N
Q
L
T
S
L
P
S
A
I
R
E
L
E
N
Site 12
T148
K
I
L
P
E
E
I
T
N
L
R
N
L
K
C
Site 13
Y157
L
R
N
L
K
C
L
Y
L
Q
H
N
E
L
T
Site 14
S182
N
L
E
D
L
D
L
S
N
N
H
L
T
T
V
Site 15
T187
D
L
S
N
N
H
L
T
T
V
P
A
S
F
S
Site 16
T188
L
S
N
N
H
L
T
T
V
P
A
S
F
S
S
Site 17
S205
S
L
V
R
L
N
L
S
S
N
E
L
K
S
L
Site 18
S206
L
V
R
L
N
L
S
S
N
E
L
K
S
L
P
Site 19
S211
L
S
S
N
E
L
K
S
L
P
A
E
I
N
R
Site 20
S229
L
K
H
L
D
C
N
S
N
L
L
E
T
I
P
Site 21
Y249
M
E
S
L
E
L
L
Y
L
R
R
N
K
L
R
Site 22
S303
L
R
D
N
K
L
K
S
V
P
D
E
I
I
L
Site 23
S320
S
L
E
R
L
D
L
S
N
N
D
I
S
S
L
Site 24
S325
D
L
S
N
N
D
I
S
S
L
P
Y
S
L
G
Site 25
S326
L
S
N
N
D
I
S
S
L
P
Y
S
L
G
N
Site 26
Y329
N
D
I
S
S
L
P
Y
S
L
G
N
L
H
L
Site 27
S330
D
I
S
S
L
P
Y
S
L
G
N
L
H
L
K
Site 28
T348
L
E
G
N
P
L
R
T
I
R
R
E
I
I
S
Site 29
S355
T
I
R
R
E
I
I
S
K
G
T
Q
E
V
L
Site 30
Y364
G
T
Q
E
V
L
K
Y
L
R
S
K
I
K
D
Site 31
S367
E
V
L
K
Y
L
R
S
K
I
K
D
D
G
P
Site 32
S375
K
I
K
D
D
G
P
S
Q
S
E
S
A
T
E
Site 33
S377
K
D
D
G
P
S
Q
S
E
S
A
T
E
T
A
Site 34
S379
D
G
P
S
Q
S
E
S
A
T
E
T
A
M
T
Site 35
T381
P
S
Q
S
E
S
A
T
E
T
A
M
T
L
P
Site 36
T383
Q
S
E
S
A
T
E
T
A
M
T
L
P
S
E
Site 37
T386
S
A
T
E
T
A
M
T
L
P
S
E
S
R
V
Site 38
S389
E
T
A
M
T
L
P
S
E
S
R
V
N
I
H
Site 39
Y406
I
T
L
K
I
L
D
Y
S
D
K
Q
A
T
L
Site 40
T428
A
V
K
S
N
I
V
T
S
I
N
F
S
K
N
Site 41
S429
V
K
S
N
I
V
T
S
I
N
F
S
K
N
Q
Site 42
S452
V
E
L
K
E
M
V
S
D
V
D
L
S
F
N
Site 43
S457
M
V
S
D
V
D
L
S
F
N
K
L
S
F
I
Site 44
T475
L
C
V
L
Q
K
L
T
F
L
D
L
R
N
N
Site 45
S486
L
R
N
N
F
L
N
S
L
P
E
E
M
E
S
Site 46
S493
S
L
P
E
E
M
E
S
L
V
R
L
Q
T
I
Site 47
T499
E
S
L
V
R
L
Q
T
I
N
L
S
F
N
R
Site 48
S503
R
L
Q
T
I
N
L
S
F
N
R
F
K
M
L
Site 49
S532
I
S
N
N
Q
V
G
S
V
D
P
Q
K
M
K
Site 50
T546
K
M
M
E
N
L
T
T
L
D
L
Q
N
N
D
Site 51
T569
G
N
C
V
N
L
R
T
L
L
L
D
G
N
P
Site 52
Y595
G
T
A
A
I
L
E
Y
L
R
D
R
I
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation