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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNOT10
Full Name:
CCR4-NOT transcription complex subunit 10
Alias:
Type:
Mass (Da):
82310
Number AA:
744
UniProt ID:
Q9H9A5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
G
A
E
K
H
E
G
T
G
Q
S
S
G
I
T
Site 2
T24
T
G
Q
S
S
G
I
T
D
Q
E
K
E
L
S
Site 3
S31
T
D
Q
E
K
E
L
S
T
N
A
F
Q
A
F
Site 4
Y61
Q
D
I
N
K
D
D
Y
K
I
I
L
N
T
A
Site 5
S75
A
V
A
E
F
F
K
S
N
Q
T
T
T
D
N
Site 6
T86
T
T
D
N
L
R
Q
T
L
N
Q
L
K
N
Q
Site 7
T127
L
Y
H
L
R
Q
Y
T
E
A
I
S
V
G
E
Site 8
Y137
I
S
V
G
E
K
L
Y
Q
F
I
E
P
F
E
Site 9
S180
A
V
L
E
K
M
I
S
Q
G
N
N
N
K
N
Site 10
S216
A
L
I
E
A
A
K
S
K
I
H
Q
Y
K
V
Site 11
Y221
A
K
S
K
I
H
Q
Y
K
V
R
A
Y
I
Q
Site 12
Y226
H
Q
Y
K
V
R
A
Y
I
Q
M
K
S
L
K
Site 13
S231
R
A
Y
I
Q
M
K
S
L
K
A
C
K
R
E
Site 14
S241
A
C
K
R
E
I
K
S
V
M
N
T
A
G
N
Site 15
T245
E
I
K
S
V
M
N
T
A
G
N
S
A
P
S
Site 16
S249
V
M
N
T
A
G
N
S
A
P
S
L
F
L
K
Site 17
S252
T
A
G
N
S
A
P
S
L
F
L
K
S
N
F
Site 18
S257
A
P
S
L
F
L
K
S
N
F
E
Y
L
R
G
Site 19
Y261
F
L
K
S
N
F
E
Y
L
R
G
N
Y
R
K
Site 20
Y266
F
E
Y
L
R
G
N
Y
R
K
A
V
K
L
L
Site 21
Y315
K
H
N
L
G
I
F
Y
F
K
K
A
L
Q
E
Site 22
S331
D
N
V
C
A
Q
L
S
A
G
S
T
D
P
G
Site 23
T335
A
Q
L
S
A
G
S
T
D
P
G
K
K
F
S
Site 24
S342
T
D
P
G
K
K
F
S
G
R
P
M
C
T
L
Site 25
Y359
N
K
R
Y
E
L
L
Y
N
C
G
I
Q
L
L
Site 26
T411
K
G
T
S
E
Q
E
T
K
G
L
P
S
K
K
Site 27
S423
S
K
K
G
I
V
Q
S
I
V
G
Q
G
Y
H
Site 28
S437
H
R
K
I
V
L
A
S
Q
S
I
Q
N
T
V
Site 29
S439
K
I
V
L
A
S
Q
S
I
Q
N
T
V
Y
N
Site 30
T443
A
S
Q
S
I
Q
N
T
V
Y
N
D
G
Q
S
Site 31
Y445
Q
S
I
Q
N
T
V
Y
N
D
G
Q
S
S
A
Site 32
S451
V
Y
N
D
G
Q
S
S
A
I
P
V
A
S
M
Site 33
T495
S
N
Q
L
G
G
N
T
E
S
S
E
S
S
E
Site 34
S497
Q
L
G
G
N
T
E
S
S
E
S
S
E
T
C
Site 35
S498
L
G
G
N
T
E
S
S
E
S
S
E
T
C
S
Site 36
S500
G
N
T
E
S
S
E
S
S
E
T
C
S
S
K
Site 37
S501
N
T
E
S
S
E
S
S
E
T
C
S
S
K
S
Site 38
T503
E
S
S
E
S
S
E
T
C
S
S
K
S
H
D
Site 39
S505
S
E
S
S
E
T
C
S
S
K
S
H
D
G
D
Site 40
S506
E
S
S
E
T
C
S
S
K
S
H
D
G
D
K
Site 41
S508
S
E
T
C
S
S
K
S
H
D
G
D
K
F
I
Site 42
S520
K
F
I
P
A
P
P
S
S
P
L
R
K
Q
E
Site 43
S521
F
I
P
A
P
P
S
S
P
L
R
K
Q
E
L
Site 44
S568
Q
Q
P
K
L
S
G
S
L
K
F
L
G
H
L
Site 45
T592
D
R
I
S
D
A
I
T
H
L
N
P
E
N
V
Site 46
S603
P
E
N
V
T
D
V
S
L
G
I
S
S
N
E
Site 47
S607
T
D
V
S
L
G
I
S
S
N
E
Q
D
Q
G
Site 48
S615
S
N
E
Q
D
Q
G
S
D
K
G
E
N
E
A
Site 49
S626
E
N
E
A
M
E
S
S
G
K
R
A
P
Q
C
Site 50
Y634
G
K
R
A
P
Q
C
Y
P
S
S
V
N
S
A
Site 51
S636
R
A
P
Q
C
Y
P
S
S
V
N
S
A
R
T
Site 52
S637
A
P
Q
C
Y
P
S
S
V
N
S
A
R
T
V
Site 53
Y653
L
F
N
L
G
S
A
Y
C
L
R
S
E
Y
D
Site 54
Y659
A
Y
C
L
R
S
E
Y
D
K
A
R
K
C
L
Site 55
T714
Q
L
L
P
A
V
K
T
H
S
E
V
R
K
K
Site 56
S716
L
P
A
V
K
T
H
S
E
V
R
K
K
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation