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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSTPIP2
Full Name:
Proline-serine-threonine phosphatase-interacting protein 2
Alias:
Macrophage actin-associated tyrosine-phosphorylated protein; MAYP; Pp37; PPIP2; Proline-serine-threonine phosphatase interacting protein 2; PSP2
Type:
Actin binding protein
Mass (Da):
38858
Number AA:
334
UniProt ID:
Q9H939
International Prot ID:
IPI00170554
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S60
G
K
D
L
L
N
L
S
R
K
K
P
C
G
Q
Site 2
T72
C
G
Q
S
E
I
N
T
L
K
R
A
L
E
V
Site 3
S97
C
H
I
Q
L
A
Q
S
L
R
E
E
A
R
K
Site 4
T119
Q
K
L
Q
R
K
K
T
E
L
I
M
D
A
I
Site 5
S131
D
A
I
H
K
Q
K
S
L
Q
F
K
K
T
M
Site 6
T137
K
S
L
Q
F
K
K
T
M
D
A
K
K
N
Y
Site 7
S159
D
E
A
E
Q
A
V
S
R
S
A
N
L
V
N
Site 8
T182
V
K
L
A
T
S
K
T
A
V
E
D
S
D
K
Site 9
S187
S
K
T
A
V
E
D
S
D
K
A
Y
M
L
H
Site 10
Y191
V
E
D
S
D
K
A
Y
M
L
H
I
G
T
L
Site 11
S245
L
S
Q
Q
C
V
T
S
D
E
M
Y
E
Q
V
Site 12
Y249
C
V
T
S
D
E
M
Y
E
Q
V
R
K
S
L
Site 13
S260
R
K
S
L
E
M
C
S
I
Q
R
D
I
E
Y
Site 14
Y267
S
I
Q
R
D
I
E
Y
F
V
N
Q
R
K
T
Site 15
T274
Y
F
V
N
Q
R
K
T
G
Q
I
P
P
A
P
Site 16
Y288
P
I
M
H
E
N
F
Y
S
S
Q
K
N
A
V
Site 17
S289
M
H
E
N
F
Y
S
S
Q
K
N
A
V
P
A
Site 18
S290
M
H
E
N
F
Y
S
S
Q
K
N
A
V
P
A
Site 19
S316
G
P
L
P
I
P
K
S
S
P
D
D
P
N
Y
Site 20
S317
P
L
P
I
P
K
S
S
P
D
D
P
N
Y
S
Site 21
Y323
S
S
P
D
D
P
N
Y
S
L
V
D
D
Y
S
Site 22
S324
S
P
D
D
P
N
Y
S
L
V
D
D
Y
S
L
Site 23
Y329
N
Y
S
L
V
D
D
Y
S
L
L
Y
Q
_
_
Site 24
Y333
V
D
D
Y
S
L
L
Y
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation