PhosphoNET

           
Protein Info 
   
Short Name:  PLEKHF2
Full Name:  Pleckstrin homology domain-containing family F member 2
Alias:  FLJ13187; PHAFIN2; PKHF2; pleckstrin homology domain containing, family F (with FYVE domain) member 2; pleckstriny domain containing, family F (with FYVE domain) member 2; ZFYVE18
Type:  Unknown function
Mass (Da):  27798
Number AA:  249
UniProt ID:  Q9H8W4
International Prot ID:  IPI00002424
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030133     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MVDRLANSEANTRRI
Site 2T12LANSEANTRRISIVE
Site 3S16EANTRRISIVENCFG
Site 4T43LIGEGVLTKLCRKKP
Site 5S89LENVTIDSIKDEGDL
Site 6T104RNGWLIKTPTKSFAV
Site 7Y112PTKSFAVYAATATEK
Site 8S135KCVTDLLSKSGKTPS
Site 9S137VTDLLSKSGKTPSNE
Site 10T140LLSKSGKTPSNEHAA
Site 11S142SKSGKTPSNEHAAVW
Site 12T167RCQKAKFTPVNRRHH
Site 13S195EKRFLLPSQSSKPVR
Site 14S197RFLLPSQSSKPVRIC
Site 15T218LSAGDMATCQPARSD
Site 16S224ATCQPARSDSYSQSL
Site 17S226CQPARSDSYSQSLKS
Site 18Y227QPARSDSYSQSLKSP
Site 19S228PARSDSYSQSLKSPL
Site 20S230RSDSYSQSLKSPLND
Site 21S233SYSQSLKSPLNDMSD
Site 22S239KSPLNDMSDDDDDDD
Site 23S247DDDDDDDSSD_____
Site 24S248DDDDDDSSD______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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