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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX31
Full Name:
Probable ATP-dependent RNA helicase DDX31
Alias:
DEAD box protein 31;Helicain
Type:
Mass (Da):
94087
Number AA:
851
UniProt ID:
Q9H8H2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
P
D
L
A
S
Q
R
H
S
E
S
F
Site 2
S11
D
L
A
S
Q
R
H
S
E
S
F
P
S
V
N
Site 3
S13
A
S
Q
R
H
S
E
S
F
P
S
V
N
S
R
Site 4
S16
R
H
S
E
S
F
P
S
V
N
S
R
P
N
V
Site 5
S44
P
G
G
G
T
R
G
S
L
V
P
T
R
P
V
Site 6
T48
T
R
G
S
L
V
P
T
R
P
V
P
P
S
P
Site 7
S54
P
T
R
P
V
P
P
S
P
A
P
L
G
T
S
Site 8
T60
P
S
P
A
P
L
G
T
S
P
Y
S
W
S
R
Site 9
S61
S
P
A
P
L
G
T
S
P
Y
S
W
S
R
S
Site 10
Y63
A
P
L
G
T
S
P
Y
S
W
S
R
S
G
P
Site 11
S64
P
L
G
T
S
P
Y
S
W
S
R
S
G
P
G
Site 12
S66
G
T
S
P
Y
S
W
S
R
S
G
P
G
R
G
Site 13
S68
S
P
Y
S
W
S
R
S
G
P
G
R
G
G
G
Site 14
S78
G
R
G
G
G
A
G
S
S
R
V
P
R
G
V
Site 15
S79
R
G
G
G
A
G
S
S
R
V
P
R
G
V
P
Site 16
S101
G
S
L
L
H
H
A
S
P
T
Q
T
M
A
A
Site 17
T105
H
H
A
S
P
T
Q
T
M
A
A
A
D
G
S
Site 18
S112
T
M
A
A
A
D
G
S
L
F
D
N
P
R
T
Site 19
T119
S
L
F
D
N
P
R
T
F
S
R
R
P
P
A
Site 20
S121
F
D
N
P
R
T
F
S
R
R
P
P
A
Q
A
Site 21
S129
R
R
P
P
A
Q
A
S
R
Q
A
K
A
T
K
Site 22
T135
A
S
R
Q
A
K
A
T
K
R
K
Y
Q
A
S
Site 23
Y139
A
K
A
T
K
R
K
Y
Q
A
S
S
E
A
P
Site 24
S142
T
K
R
K
Y
Q
A
S
S
E
A
P
P
A
K
Site 25
T154
P
A
K
R
R
N
E
T
S
F
L
P
A
K
K
Site 26
S155
A
K
R
R
N
E
T
S
F
L
P
A
K
K
T
Site 27
T162
S
F
L
P
A
K
K
T
S
V
K
E
T
Q
R
Site 28
T167
K
K
T
S
V
K
E
T
Q
R
T
F
K
G
N
Site 29
T170
S
V
K
E
T
Q
R
T
F
K
G
N
A
Q
K
Site 30
S180
G
N
A
Q
K
M
F
S
P
K
K
H
S
V
S
Site 31
S185
M
F
S
P
K
K
H
S
V
S
T
S
D
R
N
Site 32
S187
S
P
K
K
H
S
V
S
T
S
D
R
N
Q
E
Site 33
S189
K
K
H
S
V
S
T
S
D
R
N
Q
E
E
R
Site 34
T201
E
E
R
Q
C
I
K
T
S
S
L
F
K
N
N
Site 35
S203
R
Q
C
I
K
T
S
S
L
F
K
N
N
P
D
Site 36
T228
Q
V
Q
E
K
V
F
T
S
A
A
F
H
E
L
Site 37
S256
L
K
M
S
S
M
T
S
V
Q
K
Q
S
I
P
Site 38
S275
G
R
D
A
L
V
R
S
Q
T
G
S
G
K
T
Site 39
T277
D
A
L
V
R
S
Q
T
G
S
G
K
T
L
A
Site 40
S279
L
V
R
S
Q
T
G
S
G
K
T
L
A
Y
C
Site 41
S298
Q
S
L
Q
A
M
E
S
K
I
Q
R
S
D
G
Site 42
S303
M
E
S
K
I
Q
R
S
D
G
P
Y
A
L
V
Site 43
S321
T
R
E
L
A
L
Q
S
F
D
T
V
Q
K
L
Site 44
S348
M
G
G
E
K
R
K
S
E
K
A
R
L
R
K
Site 45
S362
K
G
I
N
I
L
I
S
T
P
G
R
L
V
D
Site 46
T363
G
I
N
I
L
I
S
T
P
G
R
L
V
D
H
Site 47
S373
R
L
V
D
H
I
K
S
T
K
N
I
H
F
S
Site 48
S422
K
R
Q
N
V
L
L
S
A
T
L
T
E
G
V
Site 49
S444
L
H
D
P
V
S
I
S
V
L
D
K
S
H
D
Site 50
S449
S
I
S
V
L
D
K
S
H
D
Q
L
N
P
K
Site 51
S474
P
A
G
D
K
L
D
S
F
A
I
P
E
S
L
Site 52
S480
D
S
F
A
I
P
E
S
L
K
Q
H
V
T
V
Site 53
T486
E
S
L
K
Q
H
V
T
V
V
P
S
K
L
R
Site 54
S538
L
Q
T
L
L
S
S
S
G
A
P
A
S
G
Q
Site 55
S543
S
S
S
G
A
P
A
S
G
Q
L
P
S
A
S
Site 56
S548
P
A
S
G
Q
L
P
S
A
S
M
R
L
K
F
Site 57
S550
S
G
Q
L
P
S
A
S
M
R
L
K
F
L
R
Site 58
T568
G
M
E
Q
E
E
R
T
A
V
F
Q
E
F
S
Site 59
S575
T
A
V
F
Q
E
F
S
H
S
R
R
G
V
L
Site 60
Y603
Q
V
T
W
I
V
Q
Y
N
A
P
S
S
P
A
Site 61
S608
V
Q
Y
N
A
P
S
S
P
A
E
Y
I
H
R
Site 62
Y612
A
P
S
S
P
A
E
Y
I
H
R
I
G
R
T
Site 63
T619
Y
I
H
R
I
G
R
T
A
R
I
G
C
H
G
Site 64
Y639
L
A
P
S
E
A
E
Y
V
N
S
L
A
S
H
Site 65
S642
S
E
A
E
Y
V
N
S
L
A
S
H
K
I
N
Site 66
S678
K
R
W
G
A
Q
K
S
H
A
V
G
P
Q
E
Site 67
T691
Q
E
I
R
E
R
A
T
V
L
Q
T
V
F
E
Site 68
Y700
L
Q
T
V
F
E
D
Y
V
H
S
S
E
R
R
Site 69
S703
V
F
E
D
Y
V
H
S
S
E
R
R
V
S
W
Site 70
S704
F
E
D
Y
V
H
S
S
E
R
R
V
S
W
A
Site 71
S709
H
S
S
E
R
R
V
S
W
A
K
K
A
L
Q
Site 72
S717
W
A
K
K
A
L
Q
S
F
I
Q
A
Y
A
T
Site 73
T724
S
F
I
Q
A
Y
A
T
Y
P
R
E
L
K
H
Site 74
Y725
F
I
Q
A
Y
A
T
Y
P
R
E
L
K
H
I
Site 75
S746
H
L
G
H
V
A
K
S
F
G
L
R
D
A
P
Site 76
S757
R
D
A
P
R
N
L
S
A
L
T
R
K
K
R
Site 77
T777
R
P
D
L
H
K
K
T
Q
S
K
H
S
L
A
Site 78
S782
K
K
T
Q
S
K
H
S
L
A
E
I
L
R
S
Site 79
S789
S
L
A
E
I
L
R
S
E
Y
S
S
G
M
E
Site 80
Y791
A
E
I
L
R
S
E
Y
S
S
G
M
E
A
D
Site 81
S793
I
L
R
S
E
Y
S
S
G
M
E
A
D
I
A
Site 82
S819
G
G
R
P
L
Q
H
S
L
Q
P
T
P
C
F
Site 83
T823
L
Q
H
S
L
Q
P
T
P
C
F
G
R
G
K
Site 84
T831
P
C
F
G
R
G
K
T
L
K
W
R
K
T
Q
Site 85
T837
K
T
L
K
W
R
K
T
Q
K
G
V
Q
R
D
Site 86
S845
Q
K
G
V
Q
R
D
S
K
T
S
Q
K
V
_
Site 87
T847
G
V
Q
R
D
S
K
T
S
Q
K
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation