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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC12
Full Name:
Tetratricopeptide repeat protein 12
Alias:
FLJ13859; FLJ20535; Tetratricopeptide repeat 12; Tetratricopeptide repeat domain 12; TPARM; TPR repeat 12
Type:
Unknown function
Mass (Da):
78738
Number AA:
705
UniProt ID:
Q9H892
International Prot ID:
IPI00152982
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
L
K
N
V
D
E
I
S
N
L
I
Q
E
M
N
Site 2
S28
N
L
I
Q
E
M
N
S
D
D
P
V
V
Q
Q
Site 3
T60
E
E
D
E
C
R
T
T
L
N
K
T
M
I
S
Site 4
T64
C
R
T
T
L
N
K
T
M
I
S
P
P
Q
T
Site 5
S67
T
L
N
K
T
M
I
S
P
P
Q
T
A
L
K
Site 6
T71
T
M
I
S
P
P
Q
T
A
L
K
S
A
E
E
Site 7
S75
P
P
Q
T
A
L
K
S
A
E
E
I
N
S
E
Site 8
S81
K
S
A
E
E
I
N
S
E
A
F
L
A
S
V
Site 9
Y122
E
A
F
A
E
G
N
Y
E
T
A
I
L
R
Y
Site 10
S130
E
T
A
I
L
R
Y
S
E
G
L
E
K
L
K
Site 11
Y143
L
K
D
M
K
V
L
Y
T
N
R
A
Q
A
Y
Site 12
Y150
Y
T
N
R
A
Q
A
Y
M
K
L
E
D
Y
E
Site 13
Y156
A
Y
M
K
L
E
D
Y
E
K
A
L
V
D
C
Site 14
Y177
D
E
K
C
T
K
A
Y
F
H
M
G
K
A
N
Site 15
Y190
A
N
L
A
L
K
N
Y
S
V
S
R
E
C
Y
Site 16
S191
N
L
A
L
K
N
Y
S
V
S
R
E
C
Y
K
Site 17
Y197
Y
S
V
S
R
E
C
Y
K
K
I
L
E
I
N
Site 18
S237
E
A
H
E
L
L
D
S
G
K
N
T
A
V
T
Site 19
T241
L
L
D
S
G
K
N
T
A
V
T
T
K
N
L
Site 20
S253
K
N
L
L
E
T
L
S
K
P
D
Q
I
P
L
Site 21
S292
H
N
G
F
S
I
I
S
D
N
E
V
I
R
R
Site 22
S302
E
V
I
R
R
C
F
S
T
A
G
N
D
A
V
Site 23
T303
V
I
R
R
C
F
S
T
A
G
N
D
A
V
E
Site 24
S372
L
H
L
A
Q
T
E
S
G
R
S
L
I
I
N
Site 25
S397
L
V
S
F
L
D
F
S
D
K
E
A
N
T
A
Site 26
T438
A
L
T
G
V
L
K
T
D
P
K
V
S
S
S
Site 27
S443
L
K
T
D
P
K
V
S
S
S
S
A
L
C
Q
Site 28
S444
K
T
D
P
K
V
S
S
S
S
A
L
C
Q
C
Site 29
S459
I
A
I
M
G
N
L
S
A
E
P
T
T
R
R
Site 30
T463
G
N
L
S
A
E
P
T
T
R
R
H
M
A
A
Site 31
S480
E
F
G
D
G
C
L
S
L
L
A
R
C
E
E
Site 32
S527
E
V
S
R
R
C
L
S
L
L
N
S
Q
D
G
Site 33
S551
L
S
R
T
L
S
S
S
L
K
I
V
E
E
A
Site 34
T573
K
M
M
K
F
L
K
T
G
G
E
T
A
S
R
Site 35
S579
K
T
G
G
E
T
A
S
R
Y
A
I
K
I
L
Site 36
T659
L
K
L
A
G
S
D
T
Q
K
T
A
V
Q
V
Site 37
T662
A
G
S
D
T
Q
K
T
A
V
Q
V
N
A
G
Site 38
S697
H
G
L
E
I
L
N
S
T
M
K
Y
I
S
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation