PhosphoNET

           
Protein Info 
   
Short Name:  TLE6
Full Name:  Transducin-like enhancer protein 6
Alias: 
Type: 
Mass (Da):  49827
Number AA:  449
UniProt ID:  Q9H808
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S67APGLGQESKAPGSCD
Site 2S72QESKAPGSCDPGTDP
Site 3T77PGSCDPGTDPCPEDA
Site 4S85DPCPEDASTPRPPEA
Site 5T86PCPEDASTPRPPEAS
Site 6S93TPRPPEASSSPPEGS
Site 7S94PRPPEASSSPPEGSQ
Site 8S95RPPEASSSPPEGSQD
Site 9S100SSSPPEGSQDRNTSW
Site 10T105EGSQDRNTSWGVVQE
Site 11S106GSQDRNTSWGVVQEP
Site 12S118QEPPGRASRFLQSIS
Site 13S123RASRFLQSISWDPED
Site 14S125SRFLQSISWDPEDFE
Site 15S145PDALPGQSKRLAVPC
Site 16T180SFTRHVFTCGRRGIK
Site 17S190RRGIKVWSLTGQVAE
Site 18S203AEDRFPESHLPIQTP
Site 19T209ESHLPIQTPGAFLRT
Site 20S225LLSSNSRSLLTGGYN
Site 21S289IWDLRDQSVVRDLKG
Site 22Y297VVRDLKGYPDGVKSI
Site 23S303GYPDGVKSIVVKGYN
Site 24Y309KSIVVKGYNIWTGGP
Site 25T327LRCWDQRTIMKPLEY
Site 26Y334TIMKPLEYQFKSQIM
Site 27S338PLEYQFKSQIMSLSH
Site 28S342QFKSQIMSLSHSPQE
Site 29S344KSQIMSLSHSPQEDW
Site 30S346QIMSLSHSPQEDWVL
Site 31S365NGQQWLQSTSGSQRH
Site 32S369WLQSTSGSQRHMVGQ
Site 33Y405MDDFLGVYSMPAGTK
Site 34T423VPEMSPVTCCDVSSN
Site 35S438NRLVVTGSGEHASVY
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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