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Updated November 2019
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Protein Info
Short Name:
FLJ14262
Full Name:
Protein FAM190B
Alias:
GCA14; GCAP14
Type:
Uncharacterized protein
Mass (Da):
93548
Number AA:
834
UniProt ID:
Q9H7U1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
E
E
K
T
Q
I
K
T
F
L
G
S
K
L
P
Site 2
S13
Q
I
K
T
F
L
G
S
K
L
P
K
Y
G
T
Site 3
Y18
L
G
S
K
L
P
K
Y
G
T
K
S
V
R
S
Site 4
T20
S
K
L
P
K
Y
G
T
K
S
V
R
S
T
L
Site 5
S22
L
P
K
Y
G
T
K
S
V
R
S
T
L
Q
P
Site 6
T26
G
T
K
S
V
R
S
T
L
Q
P
M
P
N
G
Site 7
T34
L
Q
P
M
P
N
G
T
P
V
N
L
L
G
T
Site 8
S45
L
L
G
T
S
K
N
S
N
V
K
S
Y
I
K
Site 9
S49
S
K
N
S
N
V
K
S
Y
I
K
N
N
G
S
Site 10
S56
S
Y
I
K
N
N
G
S
D
C
P
S
S
H
S
Site 11
S61
N
G
S
D
C
P
S
S
H
S
F
N
W
R
K
Site 12
S63
S
D
C
P
S
S
H
S
F
N
W
R
K
A
N
Site 13
Y72
N
W
R
K
A
N
K
Y
Q
L
C
A
Q
G
V
Site 14
T85
G
V
E
E
P
N
N
T
Q
N
S
H
D
K
I
Site 15
T101
D
P
E
K
R
V
P
T
Q
G
M
F
D
K
N
Site 16
S122
K
S
V
S
L
F
T
S
K
L
A
K
P
S
T
Site 17
S128
T
S
K
L
A
K
P
S
T
M
F
V
S
S
T
Site 18
T129
S
K
L
A
K
P
S
T
M
F
V
S
S
T
E
Site 19
S133
K
P
S
T
M
F
V
S
S
T
E
E
L
N
Q
Site 20
S134
P
S
T
M
F
V
S
S
T
E
E
L
N
Q
K
Site 21
S142
T
E
E
L
N
Q
K
S
F
S
G
P
S
N
L
Site 22
S144
E
L
N
Q
K
S
F
S
G
P
S
N
L
G
K
Site 23
T153
P
S
N
L
G
K
F
T
K
G
T
L
L
G
R
Site 24
T156
L
G
K
F
T
K
G
T
L
L
G
R
T
S
Y
Site 25
T161
K
G
T
L
L
G
R
T
S
Y
S
S
I
N
T
Site 26
S162
G
T
L
L
G
R
T
S
Y
S
S
I
N
T
P
Site 27
Y163
T
L
L
G
R
T
S
Y
S
S
I
N
T
P
K
Site 28
S164
L
L
G
R
T
S
Y
S
S
I
N
T
P
K
S
Site 29
S165
L
G
R
T
S
Y
S
S
I
N
T
P
K
S
Q
Site 30
T168
T
S
Y
S
S
I
N
T
P
K
S
Q
L
N
G
Site 31
S171
S
S
I
N
T
P
K
S
Q
L
N
G
F
Y
G
Site 32
Y177
K
S
Q
L
N
G
F
Y
G
N
R
S
A
G
S
Site 33
S184
Y
G
N
R
S
A
G
S
M
Q
R
P
R
A
N
Site 34
S192
M
Q
R
P
R
A
N
S
C
A
T
R
S
S
S
Site 35
T195
P
R
A
N
S
C
A
T
R
S
S
S
G
E
S
Site 36
S197
A
N
S
C
A
T
R
S
S
S
G
E
S
L
A
Site 37
S198
N
S
C
A
T
R
S
S
S
G
E
S
L
A
Q
Site 38
S199
S
C
A
T
R
S
S
S
G
E
S
L
A
Q
S
Site 39
S202
T
R
S
S
S
G
E
S
L
A
Q
S
P
D
S
Site 40
S206
S
G
E
S
L
A
Q
S
P
D
S
S
K
S
I
Site 41
S209
S
L
A
Q
S
P
D
S
S
K
S
I
N
C
E
Site 42
S210
L
A
Q
S
P
D
S
S
K
S
I
N
C
E
K
Site 43
S212
Q
S
P
D
S
S
K
S
I
N
C
E
K
M
V
Site 44
S221
N
C
E
K
M
V
R
S
Q
S
F
S
H
S
I
Site 45
S223
E
K
M
V
R
S
Q
S
F
S
H
S
I
Q
N
Site 46
S225
M
V
R
S
Q
S
F
S
H
S
I
Q
N
S
F
Site 47
S227
R
S
Q
S
F
S
H
S
I
Q
N
S
F
L
P
Site 48
S231
F
S
H
S
I
Q
N
S
F
L
P
P
S
S
I
Site 49
S236
Q
N
S
F
L
P
P
S
S
I
T
R
S
H
S
Site 50
S237
N
S
F
L
P
P
S
S
I
T
R
S
H
S
F
Site 51
T239
F
L
P
P
S
S
I
T
R
S
H
S
F
N
R
Site 52
S241
P
P
S
S
I
T
R
S
H
S
F
N
R
A
V
Site 53
S243
S
S
I
T
R
S
H
S
F
N
R
A
V
D
L
Site 54
T251
F
N
R
A
V
D
L
T
K
P
Y
Q
N
Q
Q
Site 55
Y254
A
V
D
L
T
K
P
Y
Q
N
Q
Q
L
S
I
Site 56
S260
P
Y
Q
N
Q
Q
L
S
I
R
V
P
L
R
S
Site 57
S267
S
I
R
V
P
L
R
S
S
M
L
T
R
N
S
Site 58
S268
I
R
V
P
L
R
S
S
M
L
T
R
N
S
R
Site 59
T271
P
L
R
S
S
M
L
T
R
N
S
R
Q
P
E
Site 60
S274
S
S
M
L
T
R
N
S
R
Q
P
E
V
L
N
Site 61
Y288
N
G
N
E
H
L
G
Y
G
F
N
R
P
Y
A
Site 62
Y294
G
Y
G
F
N
R
P
Y
A
A
G
G
K
K
L
Site 63
T312
N
G
P
G
V
T
S
T
L
G
Y
R
M
V
H
Site 64
Y315
G
V
T
S
T
L
G
Y
R
M
V
H
P
S
L
Site 65
S321
G
Y
R
M
V
H
P
S
L
L
K
S
S
R
S
Site 66
S325
V
H
P
S
L
L
K
S
S
R
S
P
F
S
G
Site 67
S326
H
P
S
L
L
K
S
S
R
S
P
F
S
G
T
Site 68
S328
S
L
L
K
S
S
R
S
P
F
S
G
T
M
T
Site 69
S331
K
S
S
R
S
P
F
S
G
T
M
T
V
D
G
Site 70
T333
S
R
S
P
F
S
G
T
M
T
V
D
G
N
K
Site 71
T335
S
P
F
S
G
T
M
T
V
D
G
N
K
N
S
Site 72
S342
T
V
D
G
N
K
N
S
P
A
D
T
C
V
E
Site 73
T346
N
K
N
S
P
A
D
T
C
V
E
E
D
A
T
Site 74
T353
T
C
V
E
E
D
A
T
V
L
A
K
D
R
A
Site 75
S372
Q
E
L
I
E
N
E
S
Y
R
T
K
N
N
Q
Site 76
Y373
E
L
I
E
N
E
S
Y
R
T
K
N
N
Q
T
Site 77
T375
I
E
N
E
S
Y
R
T
K
N
N
Q
T
M
K
Site 78
Y389
K
H
D
A
K
M
R
Y
L
S
D
D
V
D
D
Site 79
S391
D
A
K
M
R
Y
L
S
D
D
V
D
D
I
S
Site 80
S398
S
D
D
V
D
D
I
S
L
S
S
L
S
S
S
Site 81
S400
D
V
D
D
I
S
L
S
S
L
S
S
S
D
K
Site 82
S401
V
D
D
I
S
L
S
S
L
S
S
S
D
K
N
Site 83
S403
D
I
S
L
S
S
L
S
S
S
D
K
N
D
L
Site 84
S404
I
S
L
S
S
L
S
S
S
D
K
N
D
L
S
Site 85
S405
S
L
S
S
L
S
S
S
D
K
N
D
L
S
E
Site 86
S411
S
S
D
K
N
D
L
S
E
D
F
S
D
D
F
Site 87
S415
N
D
L
S
E
D
F
S
D
D
F
I
D
I
E
Site 88
S424
D
F
I
D
I
E
D
S
N
R
T
R
I
T
P
Site 89
T430
D
S
N
R
T
R
I
T
P
E
E
M
S
L
K
Site 90
S435
R
I
T
P
E
E
M
S
L
K
E
E
K
H
E
Site 91
S452
P
P
Q
D
M
F
D
S
P
K
E
N
E
K
A
Site 92
S461
K
E
N
E
K
A
F
S
K
T
D
E
W
I
D
Site 93
S470
T
D
E
W
I
D
I
S
V
S
D
R
S
E
C
Site 94
S472
E
W
I
D
I
S
V
S
D
R
S
E
C
T
K
Site 95
S475
D
I
S
V
S
D
R
S
E
C
T
K
H
T
S
Site 96
S482
S
E
C
T
K
H
T
S
G
N
N
L
V
S
P
Site 97
S488
T
S
G
N
N
L
V
S
P
D
T
D
Y
R
A
Site 98
T491
N
N
L
V
S
P
D
T
D
Y
R
A
G
S
S
Site 99
Y493
L
V
S
P
D
T
D
Y
R
A
G
S
S
F
E
Site 100
S497
D
T
D
Y
R
A
G
S
S
F
E
L
S
P
S
Site 101
S498
T
D
Y
R
A
G
S
S
F
E
L
S
P
S
D
Site 102
S502
A
G
S
S
F
E
L
S
P
S
D
S
S
D
G
Site 103
S504
S
S
F
E
L
S
P
S
D
S
S
D
G
T
Y
Site 104
S506
F
E
L
S
P
S
D
S
S
D
G
T
Y
M
W
Site 105
S507
E
L
S
P
S
D
S
S
D
G
T
Y
M
W
D
Site 106
T510
P
S
D
S
S
D
G
T
Y
M
W
D
E
E
G
Site 107
Y511
S
D
S
S
D
G
T
Y
M
W
D
E
E
G
L
Site 108
S529
G
N
V
H
P
V
G
S
Y
E
S
S
E
M
N
Site 109
S533
P
V
G
S
Y
E
S
S
E
M
N
S
I
D
I
Site 110
S537
Y
E
S
S
E
M
N
S
I
D
I
L
N
N
L
Site 111
S546
D
I
L
N
N
L
E
S
C
D
L
E
D
D
D
Site 112
S600
K
R
P
P
Q
R
W
S
G
Q
E
H
Y
H
L
Site 113
Y605
R
W
S
G
Q
E
H
Y
H
L
S
H
P
D
H
Site 114
Y613
H
L
S
H
P
D
H
Y
H
H
H
G
K
S
D
Site 115
S619
H
Y
H
H
H
G
K
S
D
L
S
R
G
S
P
Site 116
S622
H
H
G
K
S
D
L
S
R
G
S
P
Y
R
E
Site 117
S625
K
S
D
L
S
R
G
S
P
Y
R
E
S
P
L
Site 118
S630
R
G
S
P
Y
R
E
S
P
L
G
H
F
E
S
Site 119
S637
S
P
L
G
H
F
E
S
Y
G
G
M
P
F
F
Site 120
T673
R
H
M
V
Q
D
C
T
A
V
K
T
Q
L
L
Site 121
S694
H
Q
H
D
G
S
G
S
L
H
D
I
Q
L
S
Site 122
S701
S
L
H
D
I
Q
L
S
L
P
S
S
P
E
P
Site 123
S704
D
I
Q
L
S
L
P
S
S
P
E
P
E
D
G
Site 124
S705
I
Q
L
S
L
P
S
S
P
E
P
E
D
G
D
Site 125
Y715
P
E
D
G
D
K
V
Y
K
N
E
D
L
L
N
Site 126
T747
L
L
E
L
Q
L
A
T
Q
H
I
C
H
Q
K
Site 127
T761
K
C
K
E
E
K
C
T
Y
A
D
K
Y
T
Q
Site 128
Y762
C
K
E
E
K
C
T
Y
A
D
K
Y
T
Q
T
Site 129
Y766
K
C
T
Y
A
D
K
Y
T
Q
T
P
W
R
R
Site 130
T769
Y
A
D
K
Y
T
Q
T
P
W
R
R
I
P
G
Site 131
Y778
W
R
R
I
P
G
G
Y
S
A
P
S
F
S
P
Site 132
S779
R
R
I
P
G
G
Y
S
A
P
S
F
S
P
W
Site 133
S782
P
G
G
Y
S
A
P
S
F
S
P
W
Q
G
S
Site 134
S784
G
Y
S
A
P
S
F
S
P
W
Q
G
S
F
Q
Site 135
S789
S
F
S
P
W
Q
G
S
F
Q
G
I
P
R
T
Site 136
T796
S
F
Q
G
I
P
R
T
V
P
P
H
R
R
Q
Site 137
T804
V
P
P
H
R
R
Q
T
S
S
T
T
A
F
Q
Site 138
S805
P
P
H
R
R
Q
T
S
S
T
T
A
F
Q
Q
Site 139
S806
P
H
R
R
Q
T
S
S
T
T
A
F
Q
Q
P
Site 140
T807
H
R
R
Q
T
S
S
T
T
A
F
Q
Q
P
S
Site 141
S814
T
T
A
F
Q
Q
P
S
Q
T
H
R
S
H
P
Site 142
T816
A
F
Q
Q
P
S
Q
T
H
R
S
H
P
G
K
Site 143
S819
Q
P
S
Q
T
H
R
S
H
P
G
K
T
N
K
Site 144
T828
P
G
K
T
N
K
A
T
T
Y
R
G
P
Q
_
Site 145
T829
G
K
T
N
K
A
T
T
Y
R
G
P
Q
_
_
Site 146
Y830
K
T
N
K
A
T
T
Y
R
G
P
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation