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Updated November 2019
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Protein Info
Short Name:
SGK269
Full Name:
Tyrosine-protein kinase SgK269
Alias:
EC 2.7.10.2; FLJ21140; FLJ34483; KIAA2002; SG269; Tyrosine-protein kinase SgK269: Sugen kinase 269
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.10.2; Other group; NKF3 family
Mass (Da):
193106
Number AA:
1746
UniProt ID:
Q9H792
International Prot ID:
IPI00737545
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004715
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
GO:0006468
GO:0006793
Phosida
TranscriptoNet
STRING
Kinexus Products
Tyrosine-protein kinase SgK269; Pseudopodium-enriched atypical kinase 1 Y635 phosphosite-specific antibody AB-PK811#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PK811#Tyrosine-protein kinase SgK269 / Pseudopodium-enriched atypical kinase 1 (P632-L638, human) pY635 phosphopeptide - Powder PE-04AHC99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AHC99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
K
N
C
F
K
P
K
S
L
H
Q
L
P
P
D
Site 2
T45
I
T
H
G
N
V
K
T
N
A
N
H
S
N
N
Site 3
T58
N
N
H
R
I
R
N
T
G
N
F
R
P
P
V
Site 4
T70
P
P
V
A
K
K
P
T
I
A
V
K
P
T
M
Site 5
S112
N
R
N
R
A
A
L
S
Q
K
P
L
N
N
N
Site 6
S127
N
E
D
D
E
G
I
S
H
V
P
K
P
Y
G
Site 7
S138
K
P
Y
G
N
N
D
S
A
K
K
M
S
D
N
Site 8
T170
P
Q
I
R
G
N
E
T
N
S
R
E
T
F
L
Site 9
T175
N
E
T
N
S
R
E
T
F
L
G
R
I
N
D
Site 10
Y184
L
G
R
I
N
D
C
Y
K
R
S
L
E
R
K
Site 11
S187
I
N
D
C
Y
K
R
S
L
E
R
K
L
P
P
Site 12
S195
L
E
R
K
L
P
P
S
C
M
I
G
G
I
K
Site 13
S212
Q
G
K
H
V
I
L
S
G
S
T
E
V
I
S
Site 14
S214
K
H
V
I
L
S
G
S
T
E
V
I
S
N
E
Site 15
S219
S
G
S
T
E
V
I
S
N
E
G
G
R
F
C
Site 16
Y227
N
E
G
G
R
F
C
Y
P
E
F
S
S
G
E
Site 17
S231
R
F
C
Y
P
E
F
S
S
G
E
E
S
E
E
Site 18
S232
F
C
Y
P
E
F
S
S
G
E
E
S
E
E
D
Site 19
S236
E
F
S
S
G
E
E
S
E
E
D
V
L
F
S
Site 20
S243
S
E
E
D
V
L
F
S
N
M
E
E
E
H
E
Site 21
S251
N
M
E
E
E
H
E
S
W
D
E
S
D
E
E
Site 22
S255
E
H
E
S
W
D
E
S
D
E
E
L
L
A
M
Site 23
T279
F
A
N
F
R
A
N
T
L
S
P
V
R
F
F
Site 24
S281
N
F
R
A
N
T
L
S
P
V
R
F
F
V
D
Site 25
T293
F
V
D
K
K
W
N
T
I
P
L
R
N
K
S
Site 26
Y309
Q
R
I
C
A
V
D
Y
D
D
S
Y
D
E
I
Site 27
S312
C
A
V
D
Y
D
D
S
Y
D
E
I
L
N
G
Site 28
Y313
A
V
D
Y
D
D
S
Y
D
E
I
L
N
G
Y
Site 29
Y320
Y
D
E
I
L
N
G
Y
E
E
N
S
V
V
S
Site 30
S324
L
N
G
Y
E
E
N
S
V
V
S
Y
G
Q
G
Site 31
Y328
E
E
N
S
V
V
S
Y
G
Q
G
S
I
Q
S
Site 32
S335
Y
G
Q
G
S
I
Q
S
M
V
S
S
D
S
T
Site 33
S338
G
S
I
Q
S
M
V
S
S
D
S
T
S
P
D
Site 34
S339
S
I
Q
S
M
V
S
S
D
S
T
S
P
D
S
Site 35
S341
Q
S
M
V
S
S
D
S
T
S
P
D
S
S
L
Site 36
T342
S
M
V
S
S
D
S
T
S
P
D
S
S
L
T
Site 37
S343
M
V
S
S
D
S
T
S
P
D
S
S
L
T
E
Site 38
S346
S
D
S
T
S
P
D
S
S
L
T
E
E
S
R
Site 39
S347
D
S
T
S
P
D
S
S
L
T
E
E
S
R
S
Site 40
T349
T
S
P
D
S
S
L
T
E
E
S
R
S
E
T
Site 41
S352
D
S
S
L
T
E
E
S
R
S
E
T
A
S
S
Site 42
S354
S
L
T
E
E
S
R
S
E
T
A
S
S
L
S
Site 43
T356
T
E
E
S
R
S
E
T
A
S
S
L
S
Q
K
Site 44
S358
E
S
R
S
E
T
A
S
S
L
S
Q
K
I
C
Site 45
S359
S
R
S
E
T
A
S
S
L
S
Q
K
I
C
N
Site 46
S361
S
E
T
A
S
S
L
S
Q
K
I
C
N
G
G
Site 47
S370
K
I
C
N
G
G
L
S
P
G
N
P
G
D
S
Site 48
S377
S
P
G
N
P
G
D
S
K
D
M
K
E
I
E
Site 49
Y387
M
K
E
I
E
P
N
Y
E
S
P
S
S
N
N
Site 50
S389
E
I
E
P
N
Y
E
S
P
S
S
N
N
Q
D
Site 51
S392
P
N
Y
E
S
P
S
S
N
N
Q
D
K
D
S
Site 52
S399
S
N
N
Q
D
K
D
S
S
Q
A
S
K
S
S
Site 53
S400
N
N
Q
D
K
D
S
S
Q
A
S
K
S
S
I
Site 54
S403
D
K
D
S
S
Q
A
S
K
S
S
I
K
V
P
Site 55
S405
D
S
S
Q
A
S
K
S
S
I
K
V
P
E
T
Site 56
S406
S
S
Q
A
S
K
S
S
I
K
V
P
E
T
H
Site 57
T432
D
G
K
I
A
V
Q
T
E
K
E
E
S
K
A
Site 58
S437
V
Q
T
E
K
E
E
S
K
A
S
T
D
V
A
Site 59
T441
K
E
E
S
K
A
S
T
D
V
A
G
Q
A
V
Site 60
Y462
T
E
E
Q
A
K
P
Y
R
V
V
N
L
E
Q
Site 61
Y475
E
Q
P
L
C
K
P
Y
T
V
V
D
V
S
A
Site 62
S495
H
L
E
G
P
V
N
S
P
K
T
K
S
S
S
Site 63
T498
G
P
V
N
S
P
K
T
K
S
S
S
S
T
P
Site 64
S500
V
N
S
P
K
T
K
S
S
S
S
T
P
N
S
Site 65
S501
N
S
P
K
T
K
S
S
S
S
T
P
N
S
P
Site 66
S502
S
P
K
T
K
S
S
S
S
T
P
N
S
P
V
Site 67
S503
P
K
T
K
S
S
S
S
T
P
N
S
P
V
T
Site 68
T504
K
T
K
S
S
S
S
T
P
N
S
P
V
T
S
Site 69
S507
S
S
S
S
T
P
N
S
P
V
T
S
S
S
L
Site 70
T510
S
T
P
N
S
P
V
T
S
S
S
L
T
P
G
Site 71
S511
T
P
N
S
P
V
T
S
S
S
L
T
P
G
Q
Site 72
S513
N
S
P
V
T
S
S
S
L
T
P
G
Q
I
S
Site 73
T515
P
V
T
S
S
S
L
T
P
G
Q
I
S
A
H
Site 74
S520
S
L
T
P
G
Q
I
S
A
H
F
Q
K
S
S
Site 75
S526
I
S
A
H
F
Q
K
S
S
A
I
R
Y
Q
E
Site 76
S527
S
A
H
F
Q
K
S
S
A
I
R
Y
Q
E
V
Site 77
Y531
Q
K
S
S
A
I
R
Y
Q
E
V
W
T
S
S
Site 78
T536
I
R
Y
Q
E
V
W
T
S
S
T
S
P
R
Q
Site 79
S537
R
Y
Q
E
V
W
T
S
S
T
S
P
R
Q
K
Site 80
S540
E
V
W
T
S
S
T
S
P
R
Q
K
I
P
K
Site 81
S553
P
K
V
E
L
I
T
S
G
T
G
P
N
V
P
Site 82
T555
V
E
L
I
T
S
G
T
G
P
N
V
P
P
R
Site 83
S568
P
R
K
N
C
H
K
S
A
P
T
S
P
T
A
Site 84
T571
N
C
H
K
S
A
P
T
S
P
T
A
T
N
I
Site 85
S572
C
H
K
S
A
P
T
S
P
T
A
T
N
I
S
Site 86
T574
K
S
A
P
T
S
P
T
A
T
N
I
S
S
K
Site 87
T576
A
P
T
S
P
T
A
T
N
I
S
S
K
T
I
Site 88
T582
A
T
N
I
S
S
K
T
I
P
V
K
S
P
N
Site 89
S587
S
K
T
I
P
V
K
S
P
N
L
S
E
I
K
Site 90
S591
P
V
K
S
P
N
L
S
E
I
K
F
N
S
Y
Site 91
Y598
S
E
I
K
F
N
S
Y
N
N
A
G
M
P
P
Site 92
T615
I
I
I
H
D
E
P
T
Y
A
R
S
S
K
N
Site 93
Y616
I
I
H
D
E
P
T
Y
A
R
S
S
K
N
A
Site 94
S620
E
P
T
Y
A
R
S
S
K
N
A
I
K
V
P
Site 95
Y635
I
V
I
N
P
N
A
Y
D
N
L
A
I
Y
K
Tyrosine-protein kinase SgK269; Pseudopodium-enriched atypical kinase 1 Y635 phosphosite-specific antibody AB-PK811#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PK811#Tyrosine-protein kinase SgK269 / Pseudopodium-enriched atypical kinase 1 (P632-L638, human) pY635 phosphopeptide - Powder PE-04AHC99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AHC99
Site 96
Y641
A
Y
D
N
L
A
I
Y
K
S
F
L
G
T
S
Site 97
S643
D
N
L
A
I
Y
K
S
F
L
G
T
S
G
E
Site 98
T647
I
Y
K
S
F
L
G
T
S
G
E
L
S
V
K
Site 99
S648
Y
K
S
F
L
G
T
S
G
E
L
S
V
K
E
Site 100
S652
L
G
T
S
G
E
L
S
V
K
E
K
T
T
S
Site 101
T657
E
L
S
V
K
E
K
T
T
S
V
I
S
H
T
Site 102
S659
S
V
K
E
K
T
T
S
V
I
S
H
T
Y
E
Site 103
Y665
T
S
V
I
S
H
T
Y
E
E
I
E
T
E
S
Site 104
T670
H
T
Y
E
E
I
E
T
E
S
K
V
P
D
N
Site 105
T678
E
S
K
V
P
D
N
T
T
S
K
T
T
D
C
Site 106
S694
Q
T
K
G
F
S
N
S
T
E
H
K
R
G
S
Site 107
S701
S
T
E
H
K
R
G
S
V
A
Q
K
V
Q
E
Site 108
S718
N
C
L
N
R
G
Q
S
S
P
Q
R
S
Y
S
Site 109
S719
C
L
N
R
G
Q
S
S
P
Q
R
S
Y
S
S
Site 110
S723
G
Q
S
S
P
Q
R
S
Y
S
S
S
H
S
S
Site 111
Y724
Q
S
S
P
Q
R
S
Y
S
S
S
H
S
S
P
Site 112
S725
S
S
P
Q
R
S
Y
S
S
S
H
S
S
P
A
Site 113
S726
S
P
Q
R
S
Y
S
S
S
H
S
S
P
A
K
Site 114
S727
P
Q
R
S
Y
S
S
S
H
S
S
P
A
K
I
Site 115
S729
R
S
Y
S
S
S
H
S
S
P
A
K
I
Q
R
Site 116
S730
S
Y
S
S
S
H
S
S
P
A
K
I
Q
R
A
Site 117
T738
P
A
K
I
Q
R
A
T
Q
E
P
V
A
K
I
Site 118
S751
K
I
E
G
T
Q
E
S
Q
M
V
G
S
S
S
Site 119
S757
E
S
Q
M
V
G
S
S
S
T
R
E
K
A
S
Site 120
S758
S
Q
M
V
G
S
S
S
T
R
E
K
A
S
T
Site 121
S764
S
S
T
R
E
K
A
S
T
V
L
S
Q
I
V
Site 122
T765
S
T
R
E
K
A
S
T
V
L
S
Q
I
V
A
Site 123
S779
A
S
I
Q
P
P
Q
S
P
P
E
T
P
Q
S
Site 124
T783
P
P
Q
S
P
P
E
T
P
Q
S
G
P
K
A
Site 125
S786
S
P
P
E
T
P
Q
S
G
P
K
A
C
S
V
Site 126
S792
Q
S
G
P
K
A
C
S
V
E
E
L
Y
A
I
Site 127
Y797
A
C
S
V
E
E
L
Y
A
I
P
P
D
A
D
Site 128
S808
P
D
A
D
V
A
K
S
T
P
K
S
T
P
V
Site 129
T809
D
A
D
V
A
K
S
T
P
K
S
T
P
V
R
Site 130
S812
V
A
K
S
T
P
K
S
T
P
V
R
P
K
S
Site 131
T813
A
K
S
T
P
K
S
T
P
V
R
P
K
S
L
Site 132
S819
S
T
P
V
R
P
K
S
L
F
T
S
Q
P
S
Site 133
T822
V
R
P
K
S
L
F
T
S
Q
P
S
G
E
A
Site 134
S823
R
P
K
S
L
F
T
S
Q
P
S
G
E
A
E
Site 135
S826
S
L
F
T
S
Q
P
S
G
E
A
E
A
P
Q
Site 136
T834
G
E
A
E
A
P
Q
T
T
D
S
P
T
T
K
Site 137
T835
E
A
E
A
P
Q
T
T
D
S
P
T
T
K
V
Site 138
S837
E
A
P
Q
T
T
D
S
P
T
T
K
V
Q
K
Site 139
S847
T
K
V
Q
K
D
P
S
I
K
P
V
T
P
S
Site 140
T852
D
P
S
I
K
P
V
T
P
S
P
S
K
L
V
Site 141
S854
S
I
K
P
V
T
P
S
P
S
K
L
V
T
S
Site 142
S856
K
P
V
T
P
S
P
S
K
L
V
T
S
P
Q
Site 143
T860
P
S
P
S
K
L
V
T
S
P
Q
S
E
P
P
Site 144
S861
S
P
S
K
L
V
T
S
P
Q
S
E
P
P
A
Site 145
S864
K
L
V
T
S
P
Q
S
E
P
P
A
P
F
P
Site 146
S875
A
P
F
P
P
P
R
S
T
S
S
P
Y
H
A
Site 147
T876
P
F
P
P
P
R
S
T
S
S
P
Y
H
A
G
Site 148
S877
F
P
P
P
R
S
T
S
S
P
Y
H
A
G
N
Site 149
S878
P
P
P
R
S
T
S
S
P
Y
H
A
G
N
L
Site 150
Y880
P
R
S
T
S
S
P
Y
H
A
G
N
L
L
Q
Site 151
T891
N
L
L
Q
R
H
F
T
N
W
T
K
P
T
S
Site 152
T894
Q
R
H
F
T
N
W
T
K
P
T
S
P
T
R
Site 153
S898
T
N
W
T
K
P
T
S
P
T
R
S
T
E
A
Site 154
T900
W
T
K
P
T
S
P
T
R
S
T
E
A
E
S
Site 155
S902
K
P
T
S
P
T
R
S
T
E
A
E
S
V
L
Site 156
T903
P
T
S
P
T
R
S
T
E
A
E
S
V
L
H
Site 157
S907
T
R
S
T
E
A
E
S
V
L
H
S
E
G
S
Site 158
S911
E
A
E
S
V
L
H
S
E
G
S
R
R
A
A
Site 159
S914
S
V
L
H
S
E
G
S
R
R
A
A
D
A
K
Site 160
S927
A
K
P
K
R
W
I
S
F
K
S
F
F
R
R
Site 161
S930
K
R
W
I
S
F
K
S
F
F
R
R
R
K
T
Site 162
T937
S
F
F
R
R
R
K
T
D
E
E
D
D
K
E
Site 163
T975
V
Q
R
H
H
W
F
T
E
A
K
G
E
S
S
Site 164
S1001
D
P
A
Q
G
Q
L
S
V
D
Q
S
K
A
R
Site 165
S1005
G
Q
L
S
V
D
Q
S
K
A
R
T
D
Q
A
Site 166
S1028
E
N
A
L
L
Q
D
S
E
K
K
R
S
H
S
Site 167
S1033
Q
D
S
E
K
K
R
S
H
S
S
P
S
Q
I
Site 168
S1035
S
E
K
K
R
S
H
S
S
P
S
Q
I
P
K
Site 169
S1036
E
K
K
R
S
H
S
S
P
S
Q
I
P
K
K
Site 170
S1038
K
R
S
H
S
S
P
S
Q
I
P
K
K
I
L
Site 171
S1046
Q
I
P
K
K
I
L
S
H
M
T
H
E
V
T
Site 172
T1053
S
H
M
T
H
E
V
T
E
D
F
S
P
R
D
Site 173
S1057
H
E
V
T
E
D
F
S
P
R
D
P
R
T
V
Site 174
T1063
F
S
P
R
D
P
R
T
V
V
G
K
Q
D
G
Site 175
T1074
K
Q
D
G
R
G
C
T
S
V
T
T
A
L
S
Site 176
S1075
Q
D
G
R
G
C
T
S
V
T
T
A
L
S
L
Site 177
T1077
G
R
G
C
T
S
V
T
T
A
L
S
L
P
E
Site 178
T1078
R
G
C
T
S
V
T
T
A
L
S
L
P
E
L
Site 179
S1081
T
S
V
T
T
A
L
S
L
P
E
L
E
R
E
Site 180
S1095
E
D
G
K
E
D
I
S
D
P
M
D
P
N
P
Site 181
S1104
P
M
D
P
N
P
C
S
A
T
Y
S
N
L
G
Site 182
T1106
D
P
N
P
C
S
A
T
Y
S
N
L
G
Q
S
Site 183
Y1107
P
N
P
C
S
A
T
Y
S
N
L
G
Q
S
R
Site 184
S1108
N
P
C
S
A
T
Y
S
N
L
G
Q
S
R
A
Site 185
S1148
D
Q
E
A
P
N
A
S
Q
P
T
P
P
P
L
Site 186
T1151
A
P
N
A
S
Q
P
T
P
P
P
L
P
K
K
Site 187
T1165
K
M
I
I
R
A
N
T
E
P
I
S
K
D
L
Site 188
S1169
R
A
N
T
E
P
I
S
K
D
L
Q
K
S
M
Site 189
S1175
I
S
K
D
L
Q
K
S
M
E
S
S
L
C
V
Site 190
S1179
L
Q
K
S
M
E
S
S
L
C
V
M
A
N
P
Site 191
S1197
I
D
P
N
W
D
A
S
S
A
G
S
S
I
S
Site 192
S1198
D
P
N
W
D
A
S
S
A
G
S
S
I
S
Y
Site 193
S1201
W
D
A
S
S
A
G
S
S
I
S
Y
E
L
K
Site 194
S1202
D
A
S
S
A
G
S
S
I
S
Y
E
L
K
G
Site 195
S1204
S
S
A
G
S
S
I
S
Y
E
L
K
G
L
D
Site 196
Y1205
S
A
G
S
S
I
S
Y
E
L
K
G
L
D
I
Site 197
S1214
L
K
G
L
D
I
E
S
Y
D
S
L
E
R
P
Site 198
Y1215
K
G
L
D
I
E
S
Y
D
S
L
E
R
P
L
Site 199
S1217
L
D
I
E
S
Y
D
S
L
E
R
P
L
R
K
Site 200
S1230
R
K
E
R
P
V
P
S
A
A
N
S
I
S
S
Site 201
T1240
N
S
I
S
S
L
T
T
L
S
I
K
D
R
F
Site 202
S1242
I
S
S
L
T
T
L
S
I
K
D
R
F
S
N
Site 203
S1248
L
S
I
K
D
R
F
S
N
S
M
E
S
L
S
Site 204
S1250
I
K
D
R
F
S
N
S
M
E
S
L
S
S
R
Site 205
S1253
R
F
S
N
S
M
E
S
L
S
S
R
R
G
P
Site 206
S1255
S
N
S
M
E
S
L
S
S
R
R
G
P
S
C
Site 207
S1256
N
S
M
E
S
L
S
S
R
R
G
P
S
C
R
Site 208
S1261
L
S
S
R
R
G
P
S
C
R
Q
G
R
G
I
Site 209
S1292
E
V
V
G
K
I
R
S
L
H
T
D
A
L
K
Site 210
S1323
Q
L
R
F
G
V
D
S
W
S
D
F
R
L
T
Site 211
S1325
R
F
G
V
D
S
W
S
D
F
R
L
T
S
D
Site 212
T1330
S
W
S
D
F
R
L
T
S
D
K
P
C
C
E
Site 213
S1331
W
S
D
F
R
L
T
S
D
K
P
C
C
E
A
Site 214
Y1343
C
E
A
G
D
A
V
Y
Y
T
A
S
Y
A
K
Site 215
Y1344
E
A
G
D
A
V
Y
Y
T
A
S
Y
A
K
D
Site 216
S1347
D
A
V
Y
Y
T
A
S
Y
A
K
D
P
L
N
Site 217
Y1348
A
V
Y
Y
T
A
S
Y
A
K
D
P
L
N
N
Site 218
Y1356
A
K
D
P
L
N
N
Y
A
V
K
I
C
K
S
Site 219
S1363
Y
A
V
K
I
C
K
S
K
A
K
E
S
Q
Q
Site 220
S1368
C
K
S
K
A
K
E
S
Q
Q
Y
Y
H
S
L
Site 221
Y1371
K
A
K
E
S
Q
Q
Y
Y
H
S
L
A
V
R
Site 222
Y1372
A
K
E
S
Q
Q
Y
Y
H
S
L
A
V
R
Q
Site 223
S1374
E
S
Q
Q
Y
Y
H
S
L
A
V
R
Q
S
L
Site 224
S1438
G
K
N
P
K
P
C
S
E
A
A
S
S
Q
K
Site 225
S1442
K
P
C
S
E
A
A
S
S
Q
K
E
N
Q
G
Site 226
S1443
P
C
S
E
A
A
S
S
Q
K
E
N
Q
G
V
Site 227
S1452
K
E
N
Q
G
V
M
S
K
K
Q
R
S
H
V
Site 228
S1457
V
M
S
K
K
Q
R
S
H
V
V
V
I
T
R
Site 229
S1478
V
A
D
F
V
R
D
S
L
A
Q
H
G
K
S
Site 230
S1485
S
L
A
Q
H
G
K
S
P
D
L
Y
E
R
Q
Site 231
Y1489
H
G
K
S
P
D
L
Y
E
R
Q
V
C
L
L
Site 232
Y1527
E
N
L
L
L
V
H
Y
Q
P
G
G
T
A
Q
Site 233
S1542
G
F
G
P
A
E
P
S
P
T
S
S
Y
P
T
Site 234
T1544
G
P
A
E
P
S
P
T
S
S
Y
P
T
R
L
Site 235
S1545
P
A
E
P
S
P
T
S
S
Y
P
T
R
L
I
Site 236
S1546
A
E
P
S
P
T
S
S
Y
P
T
R
L
I
V
Site 237
Y1547
E
P
S
P
T
S
S
Y
P
T
R
L
I
V
S
Site 238
T1549
S
P
T
S
S
Y
P
T
R
L
I
V
S
N
F
Site 239
S1557
R
L
I
V
S
N
F
S
Q
A
K
Q
K
S
H
Site 240
S1563
F
S
Q
A
K
Q
K
S
H
L
V
D
P
E
I
Site 241
S1575
P
E
I
L
R
D
Q
S
R
L
A
P
E
I
I
Site 242
Y1587
E
I
I
T
A
T
Q
Y
K
K
C
D
E
F
Q
Site 243
Y1620
P
E
L
K
E
R
E
Y
T
R
A
D
L
P
R
Site 244
T1621
E
L
K
E
R
E
Y
T
R
A
D
L
P
R
I
Site 245
S1632
L
P
R
I
P
F
R
S
P
Y
S
R
G
L
Q
Site 246
Y1634
R
I
P
F
R
S
P
Y
S
R
G
L
Q
Q
L
Site 247
S1643
R
G
L
Q
Q
L
A
S
C
L
L
N
P
N
P
Site 248
S1651
C
L
L
N
P
N
P
S
E
R
I
L
I
S
D
Site 249
S1657
P
S
E
R
I
L
I
S
D
A
K
G
I
L
Q
Site 250
T1677
P
R
E
D
L
F
Q
T
F
T
A
C
P
S
L
Site 251
T1689
P
S
L
V
Q
R
N
T
L
L
Q
N
W
L
D
Site 252
S1710
M
I
K
F
A
E
K
S
L
D
R
E
G
G
I
Site 253
S1718
L
D
R
E
G
G
I
S
L
E
D
W
L
C
A
Site 254
T1733
Q
Y
L
A
F
A
T
T
D
S
L
S
C
I
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation