PhosphoNET

           
Protein Info 
   
Short Name:  GREM2
Full Name:  Gremlin-2
Alias:  CKTSF1B2; DAND3; Gremlin 2, cysteine knot superfamily; PRDC
Type: 
Mass (Da):  19320
Number AA:  168
UniProt ID:  Q9H772
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615     Uniprot OncoNet
Molecular Function:  GO:0005125     PhosphoSite+ KinaseNET
Biological Process:  GO:0030509     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S32RPAGAIPSPYKDGSS
Site 2Y34AGAIPSPYKDGSSNN
Site 3S38PSPYKDGSSNNSERW
Site 4S39SPYKDGSSNNSERWQ
Site 5S42KDGSSNNSERWQHQI
Site 6S55QIKEVLASSQEALVV
Site 7S56IKEVLASSQEALVVT
Site 8T63SQEALVVTERKYLKS
Site 9Y67LVVTERKYLKSDWCK
Site 10T75LKSDWCKTQPLRQTV
Site 11T81KTQPLRQTVSEEGCR
Site 12S83QPLRQTVSEEGCRSR
Site 13T91EEGCRSRTILNRFCY
Site 14Y105YGQCNSFYIPRHVKK
Site 15S119KEEESFQSCAFCKPQ
Site 16S159VKQCRCMSVNLSDSD
Site 17S163RCMSVNLSDSDKQ__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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