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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOL6
Full Name:
Nucleolar protein 6
Alias:
Nucleolar RNA-associated protein
Type:
Mass (Da):
127593
Number AA:
1146
UniProt ID:
Q9H6R4
International Prot ID:
IPI00152890
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000794
GO:0005730
GO:0005732
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0030515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006365
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
G
E
Q
L
R
G
A
T
G
E
P
E
V
M
E
Site 2
S35
G
K
E
G
K
K
A
S
S
R
K
R
T
L
A
Site 3
S36
K
E
G
K
K
A
S
S
R
K
R
T
L
A
E
Site 4
T40
K
A
S
S
R
K
R
T
L
A
E
P
P
A
K
Site 5
Y61
K
L
S
R
A
E
L
Y
K
E
P
T
N
E
E
Site 6
T75
E
L
N
R
L
R
E
T
E
I
L
F
H
S
S
Site 7
S98
L
L
K
E
V
R
L
S
E
K
K
K
D
R
I
Site 8
S121
Q
R
V
V
R
V
P
S
V
P
E
T
E
L
T
Site 9
T125
R
V
P
S
V
P
E
T
E
L
T
D
Q
A
W
Site 10
T128
S
V
P
E
T
E
L
T
D
Q
A
W
L
P
A
Site 11
Y199
K
D
G
L
N
Q
R
Y
F
R
K
R
A
L
Y
Site 12
Y206
Y
F
R
K
R
A
L
Y
L
A
H
L
A
H
H
Site 13
S222
A
Q
D
P
L
F
G
S
V
C
F
S
Y
T
N
Site 14
S236
N
G
C
H
L
K
P
S
L
L
L
R
P
R
G
Site 15
T250
G
K
D
E
R
L
V
T
V
R
L
H
P
C
P
Site 16
S283
S
A
W
Y
R
G
Q
S
P
A
G
D
G
S
P
Site 17
S289
Q
S
P
A
G
D
G
S
P
E
P
P
T
P
R
Site 18
T294
D
G
S
P
E
P
P
T
P
R
Y
N
T
W
V
Site 19
Y297
P
E
P
P
T
P
R
Y
N
T
W
V
L
Q
D
Site 20
T299
P
P
T
P
R
Y
N
T
W
V
L
Q
D
T
V
Site 21
T305
N
T
W
V
L
Q
D
T
V
L
E
S
H
L
Q
Site 22
T367
V
S
T
R
K
I
H
T
T
M
S
G
Y
Q
V
Site 23
T368
S
T
R
K
I
H
T
T
M
S
G
Y
Q
V
L
Site 24
S370
R
K
I
H
T
T
M
S
G
Y
Q
V
L
R
S
Site 25
S444
V
Q
H
E
A
R
L
S
M
M
L
L
D
S
R
Site 26
S450
L
S
M
M
L
L
D
S
R
A
D
D
G
F
H
Site 27
Y502
L
Q
D
N
G
G
D
Y
V
S
A
A
L
G
P
Site 28
S528
R
L
N
L
L
A
H
S
R
P
P
V
P
E
W
Site 29
S538
P
V
P
E
W
D
I
S
Q
D
P
P
K
H
K
Site 30
S547
D
P
P
K
H
K
D
S
G
T
L
T
L
G
L
Site 31
T549
P
K
H
K
D
S
G
T
L
T
L
G
L
L
L
Site 32
T551
H
K
D
S
G
T
L
T
L
G
L
L
L
R
P
Site 33
S563
L
R
P
E
G
L
T
S
V
L
E
L
G
P
E
Site 34
S585
K
F
R
Q
F
W
G
S
R
S
E
L
R
R
F
Site 35
S587
R
Q
F
W
G
S
R
S
E
L
R
R
F
Q
D
Site 36
S609
V
W
E
A
A
S
M
S
Q
K
R
L
I
P
H
Site 37
S653
Q
G
L
K
E
T
S
S
T
G
E
E
A
L
V
Site 38
T654
G
L
K
E
T
S
S
T
G
E
E
A
L
V
A
Site 39
S670
V
R
C
Y
D
D
L
S
R
L
L
W
G
L
E
Site 40
Y695
G
A
H
P
V
L
R
Y
T
E
V
F
P
P
T
Site 41
T696
A
H
P
V
L
R
Y
T
E
V
F
P
P
T
P
Site 42
T702
Y
T
E
V
F
P
P
T
P
V
R
P
A
F
S
Site 43
S709
T
P
V
R
P
A
F
S
F
Y
E
T
L
R
E
Site 44
T713
P
A
F
S
F
Y
E
T
L
R
E
R
S
S
L
Site 45
S718
Y
E
T
L
R
E
R
S
S
L
L
P
R
L
D
Site 46
S719
E
T
L
R
E
R
S
S
L
L
P
R
L
D
K
Site 47
T770
L
R
L
A
E
L
L
T
Q
Q
H
G
L
Q
C
Site 48
T780
H
G
L
Q
C
R
A
T
A
T
H
T
D
V
L
Site 49
Y799
V
F
R
I
R
V
A
Y
Q
R
E
P
Q
I
L
Site 50
S811
Q
I
L
K
E
V
Q
S
P
E
G
M
I
S
L
Site 51
S817
Q
S
P
E
G
M
I
S
L
R
D
T
A
A
S
Site 52
T821
G
M
I
S
L
R
D
T
A
A
S
L
R
L
E
Site 53
S824
S
L
R
D
T
A
A
S
L
R
L
E
R
D
T
Site 54
T831
S
L
R
L
E
R
D
T
R
Q
L
P
L
L
T
Site 55
S839
R
Q
L
P
L
L
T
S
A
L
H
G
L
Q
Q
Site 56
S852
Q
Q
Q
H
P
A
F
S
G
V
A
R
L
A
K
Site 57
T891
F
L
H
P
E
P
F
T
P
P
S
S
P
Q
V
Site 58
S894
P
E
P
F
T
P
P
S
S
P
Q
V
G
F
L
Site 59
S895
E
P
F
T
P
P
S
S
P
Q
V
G
F
L
R
Site 60
T926
V
N
L
N
N
E
L
T
V
E
E
Q
V
E
I
Site 61
T951
L
P
V
M
V
I
V
T
P
Q
D
R
K
N
S
Site 62
S958
T
P
Q
D
R
K
N
S
V
W
T
Q
D
G
P
Site 63
T999
R
G
P
G
D
I
R
T
V
F
R
P
P
L
D
Site 64
S1015
Y
D
V
L
I
R
L
S
P
R
H
I
P
R
H
Site 65
S1028
R
H
R
Q
A
V
D
S
P
A
A
S
F
C
R
Site 66
S1032
A
V
D
S
P
A
A
S
F
C
R
G
L
L
S
Site 67
S1039
S
F
C
R
G
L
L
S
Q
P
G
P
S
S
L
Site 68
Y1058
G
Y
D
P
P
Q
L
Y
L
T
Q
L
R
E
A
Site 69
T1060
D
P
P
Q
L
Y
L
T
Q
L
R
E
A
F
G
Site 70
Y1074
G
D
L
A
L
F
F
Y
D
Q
H
G
G
E
V
Site 71
S1090
G
V
L
W
K
P
T
S
F
Q
P
Q
P
F
K
Site 72
S1100
P
Q
P
F
K
A
S
S
T
K
G
R
M
V
M
Site 73
S1108
T
K
G
R
M
V
M
S
R
G
G
E
L
V
M
Site 74
T1136
L
G
E
G
L
V
Q
T
V
E
A
R
S
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation