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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REEP4
Full Name:
Receptor expression-enhancing protein 4
Alias:
C8orf20; FLJ22246; FLJ22277; PP432; Receptor accessory protein 4
Type:
Unknown function
Mass (Da):
29395
Number AA:
257
UniProt ID:
Q9H6H4
International Prot ID:
IPI00100674
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S95
Y
R
K
F
V
H
P
S
L
S
R
H
E
K
E
Site 2
S97
K
F
V
H
P
S
L
S
R
H
E
K
E
I
D
Site 3
Y106
H
E
K
E
I
D
A
Y
I
V
Q
A
K
E
R
Site 4
S114
I
V
Q
A
K
E
R
S
Y
E
T
V
L
S
F
Site 5
Y115
V
Q
A
K
E
R
S
Y
E
T
V
L
S
F
G
Site 6
T117
A
K
E
R
S
Y
E
T
V
L
S
F
G
K
R
Site 7
S120
R
S
Y
E
T
V
L
S
F
G
K
R
G
L
N
Site 8
S140
A
V
Q
A
A
T
K
S
Q
G
A
L
A
G
R
Site 9
S150
A
L
A
G
R
L
R
S
F
S
M
Q
D
L
R
Site 10
S152
A
G
R
L
R
S
F
S
M
Q
D
L
R
S
I
Site 11
S158
F
S
M
Q
D
L
R
S
I
S
D
A
P
A
P
Site 12
S160
M
Q
D
L
R
S
I
S
D
A
P
A
P
A
Y
Site 13
Y167
S
D
A
P
A
P
A
Y
H
D
P
L
Y
L
E
Site 14
Y172
P
A
Y
H
D
P
L
Y
L
E
D
Q
V
S
H
Site 15
S178
L
Y
L
E
D
Q
V
S
H
R
R
P
P
I
G
Site 16
Y186
H
R
R
P
P
I
G
Y
R
A
G
G
L
Q
D
Site 17
S194
R
A
G
G
L
Q
D
S
D
T
E
D
E
C
W
Site 18
T196
G
G
L
Q
D
S
D
T
E
D
E
C
W
S
D
Site 19
S202
D
T
E
D
E
C
W
S
D
T
E
A
V
P
R
Site 20
T204
E
D
E
C
W
S
D
T
E
A
V
P
R
A
P
Site 21
S222
R
E
K
P
L
I
R
S
Q
S
L
R
V
V
K
Site 22
S224
K
P
L
I
R
S
Q
S
L
R
V
V
K
R
K
Site 23
T238
K
P
P
V
R
E
G
T
S
R
S
L
K
V
R
Site 24
S241
V
R
E
G
T
S
R
S
L
K
V
R
T
R
K
Site 25
T246
S
R
S
L
K
V
R
T
R
K
K
T
V
P
S
Site 26
T250
K
V
R
T
R
K
K
T
V
P
S
D
V
D
S
Site 27
S253
T
R
K
K
T
V
P
S
D
V
D
S
_
_
_
Site 28
S257
T
V
P
S
D
V
D
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation