PhosphoNET

           
Protein Info 
   
Short Name:  TMEM149
Full Name:  Transmembrane protein 149
Alias:  U2 small nuclear RNA auxiliary factor 1-like 4
Type: 
Mass (Da):  37895
Number AA:  355
UniProt ID:  Q9H665
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y197PKEKADPYPYPGLVC
Site 2Y199EKADPYPYPGLVCGV
Site 3T209LVCGVPNTHTPSSSH
Site 4T211CGVPNTHTPSSSHLS
Site 5S213VPNTHTPSSSHLSSP
Site 6S214PNTHTPSSSHLSSPG
Site 7S215NTHTPSSSHLSSPGA
Site 8S218TPSSSHLSSPGALET
Site 9S219PSSSHLSSPGALETG
Site 10T228GALETGDTWKEASLL
Site 11S233GDTWKEASLLPLLSR
Site 12S243PLLSRELSSLASQPL
Site 13S244LLSRELSSLASQPLS
Site 14S247RELSSLASQPLSRLL
Site 15S251SLASQPLSRLLDELE
Site 16T281GGGMAHGTTRHLAAR
Site 17Y289TRHLAARYGLPAAWS
Site 18S301AWSTFAYSLRPSRSP
Site 19S305FAYSLRPSRSPLRAL
Site 20S307YSLRPSRSPLRALIE
Site 21S324VAREPSASLGQLGTH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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