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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM39B
Full Name:
Protein FAM124B
Alias:
CXYorf1; Family with sequence similarity 39, member B
Type:
Mass (Da):
50525
Number AA:
468
UniProt ID:
Q9H5Z6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
L
A
N
S
G
H
G
S
L
L
Q
R
T
L
D
Site 2
T27
H
G
S
L
L
Q
R
T
L
D
Q
L
L
D
C
Site 3
S45
E
V
R
L
F
Q
V
S
E
R
A
S
P
V
K
Site 4
S49
F
Q
V
S
E
R
A
S
P
V
K
Y
C
E
K
Site 5
Y53
E
R
A
S
P
V
K
Y
C
E
K
S
H
S
K
Site 6
S57
P
V
K
Y
C
E
K
S
H
S
K
R
S
R
F
Site 7
S59
K
Y
C
E
K
S
H
S
K
R
S
R
F
P
G
Site 8
S62
E
K
S
H
S
K
R
S
R
F
P
G
M
S
V
Site 9
S88
R
L
F
R
V
L
D
S
L
Q
H
S
P
W
Q
Site 10
S92
V
L
D
S
L
Q
H
S
P
W
Q
C
Y
P
T
Site 11
T99
S
P
W
Q
C
Y
P
T
Q
D
T
R
G
R
L
Site 12
Y109
T
R
G
R
L
C
P
Y
F
F
A
N
Q
E
F
Site 13
S118
F
A
N
Q
E
F
Y
S
L
D
S
Q
L
P
I
Site 14
S121
Q
E
F
Y
S
L
D
S
Q
L
P
I
W
G
V
Site 15
Y143
E
I
L
R
V
T
L
Y
C
S
F
D
N
Y
E
Site 16
S145
L
R
V
T
L
Y
C
S
F
D
N
Y
E
D
A
Site 17
Y149
L
Y
C
S
F
D
N
Y
E
D
A
I
R
L
Y
Site 18
Y156
Y
E
D
A
I
R
L
Y
E
M
I
L
Q
R
E
Site 19
T165
M
I
L
Q
R
E
A
T
L
Q
K
S
N
F
C
Site 20
S187
K
S
F
A
L
Q
L
S
L
K
Q
L
P
P
G
Site 21
S196
K
Q
L
P
P
G
M
S
V
D
P
K
E
S
S
Site 22
S203
S
V
D
P
K
E
S
S
V
L
Q
F
K
V
Q
Site 23
T233
I
S
S
T
R
W
Q
T
Q
D
Y
D
G
N
K
Site 24
Y236
T
R
W
Q
T
Q
D
Y
D
G
N
K
I
L
L
Site 25
T270
L
P
L
G
S
R
L
T
S
V
S
A
K
R
T
Site 26
S271
P
L
G
S
R
L
T
S
V
S
A
K
R
T
S
Site 27
S273
G
S
R
L
T
S
V
S
A
K
R
T
S
E
P
Site 28
T277
T
S
V
S
A
K
R
T
S
E
P
R
S
Q
R
Site 29
S278
S
V
S
A
K
R
T
S
E
P
R
S
Q
R
N
Site 30
S282
K
R
T
S
E
P
R
S
Q
R
N
Q
G
K
R
Site 31
S290
Q
R
N
Q
G
K
R
S
Q
G
H
S
L
E
L
Site 32
S294
G
K
R
S
Q
G
H
S
L
E
L
P
E
P
S
Site 33
S301
S
L
E
L
P
E
P
S
G
S
P
T
S
D
R
Site 34
S303
E
L
P
E
P
S
G
S
P
T
S
D
R
C
A
Site 35
T305
P
E
P
S
G
S
P
T
S
D
R
C
A
G
T
Site 36
S306
E
P
S
G
S
P
T
S
D
R
C
A
G
T
S
Site 37
T312
T
S
D
R
C
A
G
T
S
W
K
S
P
G
R
Site 38
S313
S
D
R
C
A
G
T
S
W
K
S
P
G
R
S
Site 39
S316
C
A
G
T
S
W
K
S
P
G
R
S
F
Q
V
Site 40
S320
S
W
K
S
P
G
R
S
F
Q
V
S
S
P
A
Site 41
S324
P
G
R
S
F
Q
V
S
S
P
A
M
G
A
H
Site 42
S325
G
R
S
F
Q
V
S
S
P
A
M
G
A
H
L
Site 43
S335
M
G
A
H
L
H
L
S
S
H
H
L
E
S
G
Site 44
S336
G
A
H
L
H
L
S
S
H
H
L
E
S
G
A
Site 45
S341
L
S
S
H
H
L
E
S
G
A
R
M
K
V
L
Site 46
S353
K
V
L
N
R
E
N
S
F
Q
K
L
E
A
E
Site 47
S372
T
G
L
T
I
I
N
S
E
P
R
Q
T
Y
F
Site 48
T377
I
N
S
E
P
R
Q
T
Y
F
G
G
F
P
R
Site 49
Y378
N
S
E
P
R
Q
T
Y
F
G
G
F
P
R
D
Site 50
T388
G
F
P
R
D
L
Q
T
S
Q
P
P
F
C
L
Site 51
S389
F
P
R
D
L
Q
T
S
Q
P
P
F
C
L
P
Site 52
S405
S
S
L
G
V
A
T
S
K
N
N
S
V
L
K
Site 53
S409
V
A
T
S
K
N
N
S
V
L
K
E
R
V
S
Site 54
S416
S
V
L
K
E
R
V
S
P
L
P
L
A
G
Q
Site 55
T428
A
G
Q
R
D
L
G
T
R
K
T
I
S
E
C
Site 56
T431
R
D
L
G
T
R
K
T
I
S
E
C
L
L
H
Site 57
S433
L
G
T
R
K
T
I
S
E
C
L
L
H
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation