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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DHX35
Full Name:
Probable ATP-dependent RNA helicase DHX35
Alias:
DEAH box protein 35
Type:
Mass (Da):
78910
Number AA:
703
UniProt ID:
Q9H5Z1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
V
K
F
W
R
P
G
T
E
G
P
G
V
S
I
Site 2
S21
G
T
E
G
P
G
V
S
I
S
E
E
R
Q
S
Site 3
S23
E
G
P
G
V
S
I
S
E
E
R
Q
S
L
A
Site 4
S28
S
I
S
E
E
R
Q
S
L
A
E
N
S
G
T
Site 5
T35
S
L
A
E
N
S
G
T
T
V
V
Y
N
P
Y
Site 6
S46
Y
N
P
Y
A
A
L
S
I
E
Q
Q
R
Q
K
Site 7
Y65
K
L
R
N
H
I
L
Y
L
I
E
N
Y
Q
T
Site 8
S84
G
E
T
G
C
G
K
S
T
Q
I
P
Q
Y
L
Site 9
T85
E
T
G
C
G
K
S
T
Q
I
P
Q
Y
L
A
Site 10
Y90
K
S
T
Q
I
P
Q
Y
L
A
E
A
G
W
T
Site 11
T106
E
G
R
V
V
G
V
T
Q
P
R
R
V
A
A
Site 12
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Site 13
Y249
T
F
P
V
D
I
F
Y
L
Q
S
P
V
P
D
Site 14
Y257
L
Q
S
P
V
P
D
Y
I
K
S
T
V
E
T
Site 15
S260
P
V
P
D
Y
I
K
S
T
V
E
T
V
V
K
Site 16
T264
Y
I
K
S
T
V
E
T
V
V
K
I
H
Q
T
Site 17
S292
E
E
V
E
T
V
V
S
M
L
I
E
Q
A
R
Site 18
T304
Q
A
R
A
L
A
R
T
G
M
K
R
H
L
R
Site 19
S332
M
K
V
F
E
R
V
S
R
S
V
R
K
V
I
Site 20
Y356
I
T
I
S
G
I
V
Y
V
I
D
C
G
F
V
Site 21
Y368
G
F
V
K
L
R
A
Y
N
P
R
T
A
I
E
Site 22
S399
G
R
G
G
R
S
R
S
G
K
C
Y
R
L
Y
Site 23
Y403
R
S
R
S
G
K
C
Y
R
L
Y
T
E
E
A
Site 24
Y406
S
G
K
C
Y
R
L
Y
T
E
E
A
F
D
K
Site 25
T407
G
K
C
Y
R
L
Y
T
E
E
A
F
D
K
L
Site 26
S417
A
F
D
K
L
P
Q
S
T
V
P
E
M
Q
R
Site 27
S449
V
L
R
F
H
F
M
S
P
P
P
A
Q
S
M
Site 28
T476
L
D
K
D
C
R
L
T
E
P
L
G
M
R
I
Site 29
S505
E
S
G
N
F
G
C
S
Q
E
I
L
S
I
A
Site 30
S529
V
V
P
P
N
Q
K
S
H
A
I
R
V
H
R
Site 31
T547
V
E
E
G
D
H
L
T
M
L
N
I
Y
E
A
Site 32
Y552
H
L
T
M
L
N
I
Y
E
A
F
I
K
H
N
Site 33
T580
K
G
L
V
R
A
A
T
V
R
E
Q
L
K
K
Site 34
S598
K
F
Q
V
P
R
K
S
S
E
G
D
P
D
L
Site 35
S599
F
Q
V
P
R
K
S
S
E
G
D
P
D
L
V
Site 36
S623
A
N
A
A
R
F
H
S
T
G
A
Y
R
T
I
Site 37
Y627
R
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Site 38
S642
E
L
H
I
H
P
A
S
V
L
Y
A
E
K
P
Site 39
Y645
I
H
P
A
S
V
L
Y
A
E
K
P
P
R
W
Site 40
Y655
K
P
P
R
W
V
I
Y
N
E
V
I
Q
T
S
Site 41
Y664
E
V
I
Q
T
S
K
Y
Y
M
R
D
V
T
A
Site 42
Y665
V
I
Q
T
S
K
Y
Y
M
R
D
V
T
A
I
Site 43
T670
K
Y
Y
M
R
D
V
T
A
I
E
S
A
W
L
Site 44
Y685
L
E
L
A
P
H
F
Y
Q
Q
G
T
H
L
S
Site 45
S692
Y
Q
Q
G
T
H
L
S
L
K
A
K
R
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation