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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IKZF5
Full Name:
Zinc finger protein Pegasus
Alias:
Ikaros family zinc finger protein 5
Type:
Mass (Da):
46510
Number AA:
419
UniProt ID:
Q9H5V7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
F
V
K
D
F
Q
E
Y
L
T
Q
Q
T
H
H
Site 2
S30
T
H
H
V
N
M
I
S
G
S
V
S
G
D
K
Site 3
S32
H
V
N
M
I
S
G
S
V
S
G
D
K
E
A
Site 4
S34
N
M
I
S
G
S
V
S
G
D
K
E
A
E
A
Site 5
S58
Q
N
G
L
D
H
P
S
V
E
V
S
L
D
E
Site 6
S62
D
H
P
S
V
E
V
S
L
D
E
N
S
G
M
Site 7
T77
L
V
D
G
F
E
R
T
F
D
G
K
L
K
C
Site 8
Y86
D
G
K
L
K
C
R
Y
C
N
Y
A
S
K
G
Site 9
Y89
L
K
C
R
Y
C
N
Y
A
S
K
G
T
A
R
Site 10
T105
I
E
H
I
R
I
H
T
G
E
K
P
H
R
C
Site 11
Y121
L
C
P
F
A
S
A
Y
E
R
H
L
E
A
H
Site 12
S131
H
L
E
A
H
M
R
S
H
T
G
E
K
P
Y
Site 13
T133
E
A
H
M
R
S
H
T
G
E
K
P
Y
K
C
Site 14
Y138
S
H
T
G
E
K
P
Y
K
C
E
L
C
S
F
Site 15
S144
P
Y
K
C
E
L
C
S
F
R
C
S
D
R
S
Site 16
S148
E
L
C
S
F
R
C
S
D
R
S
N
L
S
H
Site 17
S151
S
F
R
C
S
D
R
S
N
L
S
H
H
R
R
Site 18
S154
C
S
D
R
S
N
L
S
H
H
R
R
R
K
H
Site 19
T169
K
M
V
P
I
K
G
T
R
S
S
L
S
S
K
Site 20
S171
V
P
I
K
G
T
R
S
S
L
S
S
K
K
M
Site 21
S172
P
I
K
G
T
R
S
S
L
S
S
K
K
M
W
Site 22
S174
K
G
T
R
S
S
L
S
S
K
K
M
W
G
V
Site 23
S175
G
T
R
S
S
L
S
S
K
K
M
W
G
V
L
Site 24
S187
G
V
L
Q
K
K
T
S
N
L
G
Y
S
R
R
Site 25
Y191
K
K
T
S
N
L
G
Y
S
R
R
A
L
I
N
Site 26
S192
K
T
S
N
L
G
Y
S
R
R
A
L
I
N
L
Site 27
S203
L
I
N
L
S
P
P
S
M
V
V
Q
K
P
D
Site 28
Y211
M
V
V
Q
K
P
D
Y
L
N
D
F
T
H
E
Site 29
T216
P
D
Y
L
N
D
F
T
H
E
I
P
N
I
Q
Site 30
S226
I
P
N
I
Q
T
D
S
Y
E
S
M
A
K
T
Site 31
Y227
P
N
I
Q
T
D
S
Y
E
S
M
A
K
T
T
Site 32
T233
S
Y
E
S
M
A
K
T
T
P
T
G
G
L
P
Site 33
T234
Y
E
S
M
A
K
T
T
P
T
G
G
L
P
R
Site 34
S256
D
N
P
L
N
Q
L
S
T
L
A
G
Q
L
S
Site 35
T257
N
P
L
N
Q
L
S
T
L
A
G
Q
L
S
S
Site 36
S263
S
T
L
A
G
Q
L
S
S
L
P
P
E
N
Q
Site 37
S264
T
L
A
G
Q
L
S
S
L
P
P
E
N
Q
N
Site 38
S274
P
E
N
Q
N
P
A
S
P
D
V
V
P
C
P
Site 39
S307
V
S
A
S
I
P
Q
S
S
S
P
T
S
P
E
Site 40
S308
S
A
S
I
P
Q
S
S
S
P
T
S
P
E
P
Site 41
S309
A
S
I
P
Q
S
S
S
P
T
S
P
E
P
R
Site 42
T311
I
P
Q
S
S
S
P
T
S
P
E
P
R
P
S
Site 43
S312
P
Q
S
S
S
P
T
S
P
E
P
R
P
S
H
Site 44
S318
T
S
P
E
P
R
P
S
H
S
Q
R
N
Y
S
Site 45
S320
P
E
P
R
P
S
H
S
Q
R
N
Y
S
P
V
Site 46
Y324
P
S
H
S
Q
R
N
Y
S
P
V
A
G
P
S
Site 47
S325
S
H
S
Q
R
N
Y
S
P
V
A
G
P
S
S
Site 48
S331
Y
S
P
V
A
G
P
S
S
E
P
S
A
H
T
Site 49
S332
S
P
V
A
G
P
S
S
E
P
S
A
H
T
S
Site 50
S335
A
G
P
S
S
E
P
S
A
H
T
S
T
P
S
Site 51
T338
S
S
E
P
S
A
H
T
S
T
P
S
I
G
N
Site 52
S339
S
E
P
S
A
H
T
S
T
P
S
I
G
N
S
Site 53
T340
E
P
S
A
H
T
S
T
P
S
I
G
N
S
Q
Site 54
S342
S
A
H
T
S
T
P
S
I
G
N
S
Q
P
S
Site 55
S346
S
T
P
S
I
G
N
S
Q
P
S
T
P
A
P
Site 56
S349
S
I
G
N
S
Q
P
S
T
P
A
P
A
L
P
Site 57
T350
I
G
N
S
Q
P
S
T
P
A
P
A
L
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation