KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACTL8
Full Name:
Actin-like protein 8
Alias:
Cancer/testis antigen 57
Type:
Mass (Da):
41342
Number AA:
366
UniProt ID:
Q9H568
International Prot ID:
IPI00329820
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
T
V
I
I
D
H
G
S
G
F
L
K
A
G
T
Site 2
T19
S
G
F
L
K
A
G
T
A
G
W
N
E
P
Q
Site 3
Y35
V
F
P
N
I
V
N
Y
L
P
C
K
E
N
P
Site 4
S45
C
K
E
N
P
G
P
S
Y
A
R
R
R
V
S
Site 5
Y46
K
E
N
P
G
P
S
Y
A
R
R
R
V
S
L
Site 6
S52
S
Y
A
R
R
R
V
S
L
G
I
D
I
C
H
Site 7
T62
I
D
I
C
H
P
D
T
F
S
Y
P
I
E
R
Site 8
S64
I
C
H
P
D
T
F
S
Y
P
I
E
R
G
R
Site 9
Y65
C
H
P
D
T
F
S
Y
P
I
E
R
G
R
I
Site 10
T103
P
P
V
I
I
T
E
T
P
L
R
E
P
A
D
Site 11
S169
Q
G
R
P
L
P
A
S
G
K
T
L
E
F
A
Site 12
S181
E
F
A
G
Q
D
L
S
A
Y
L
L
K
S
L
Site 13
Y183
A
G
Q
D
L
S
A
Y
L
L
K
S
L
F
K
Site 14
S187
L
S
A
Y
L
L
K
S
L
F
K
E
D
C
D
Site 15
Y213
V
T
Q
M
N
K
C
Y
V
P
Q
N
L
G
E
Site 16
S230
D
F
R
E
R
Q
Q
S
A
L
D
E
S
N
T
Site 17
T237
S
A
L
D
E
S
N
T
Y
Q
L
P
D
G
S
Site 18
Y238
A
L
D
E
S
N
T
Y
Q
L
P
D
G
S
R
Site 19
S244
T
Y
Q
L
P
D
G
S
R
V
E
L
T
P
M
Site 20
T249
D
G
S
R
V
E
L
T
P
M
Q
R
V
A
P
Site 21
S261
V
A
P
E
M
F
F
S
P
Q
V
F
E
Q
P
Site 22
S271
V
F
E
Q
P
G
P
S
I
P
R
A
I
V
E
Site 23
Y304
A
C
G
G
N
T
L
Y
P
G
F
T
K
R
L
Site 24
T308
N
T
L
Y
P
G
F
T
K
R
L
F
R
E
L
Site 25
S321
E
L
M
G
D
H
V
S
S
T
K
A
T
V
W
Site 26
T326
H
V
S
S
T
K
A
T
V
W
E
G
S
N
R
Site 27
S336
E
G
S
N
R
N
F
S
V
W
L
G
A
S
V
Site 28
S348
A
S
V
V
A
H
L
S
T
Y
Q
S
E
W
M
Site 29
Y350
V
V
A
H
L
S
T
Y
Q
S
E
W
M
S
R
Site 30
S352
A
H
L
S
T
Y
Q
S
E
W
M
S
R
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation