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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMOC1
Full Name:
SPARC-related modular calcium-binding protein 1
Alias:
Secreted modular calcium-binding protein 1; SMOC-1
Type:
Mass (Da):
48163
Number AA:
434
UniProt ID:
Q9H4F8
International Prot ID:
Isoform1 - IPI00301812
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
S
P
A
R
G
H
R
T
T
G
P
R
F
L
I
Site 2
T30
P
A
R
G
H
R
T
T
G
P
R
F
L
I
S
Site 3
S37
T
G
P
R
F
L
I
S
D
R
D
P
Q
C
N
Site 4
T50
C
N
L
H
C
S
R
T
Q
P
K
P
I
C
A
Site 5
S58
Q
P
K
P
I
C
A
S
D
G
R
S
Y
E
S
Site 6
Y63
C
A
S
D
G
R
S
Y
E
S
M
C
E
Y
Q
Site 7
S65
S
D
G
R
S
Y
E
S
M
C
E
Y
Q
R
A
Site 8
Y69
S
Y
E
S
M
C
E
Y
Q
R
A
K
C
R
D
Site 9
T78
R
A
K
C
R
D
P
T
L
G
V
V
H
R
G
Site 10
S147
T
P
D
G
K
P
I
S
G
S
S
V
Q
N
K
Site 11
S149
D
G
K
P
I
S
G
S
S
V
Q
N
K
T
P
Site 12
S150
G
K
P
I
S
G
S
S
V
Q
N
K
T
P
V
Site 13
T155
G
S
S
V
Q
N
K
T
P
V
C
S
G
S
V
Site 14
S161
K
T
P
V
C
S
G
S
V
T
D
K
P
L
S
Site 15
T163
P
V
C
S
G
S
V
T
D
K
P
L
S
Q
G
Site 16
S168
S
V
T
D
K
P
L
S
Q
G
N
S
G
R
K
Site 17
S172
K
P
L
S
Q
G
N
S
G
R
K
D
D
G
S
Site 18
S179
S
G
R
K
D
D
G
S
K
P
T
P
T
M
E
Site 19
T182
K
D
D
G
S
K
P
T
P
T
M
E
T
Q
P
Site 20
T184
D
G
S
K
P
T
P
T
M
E
T
Q
P
V
F
Site 21
S211
K
H
L
V
I
K
D
S
K
L
N
N
T
N
I
Site 22
T216
K
D
S
K
L
N
N
T
N
I
R
N
S
E
K
Site 23
Y225
I
R
N
S
E
K
V
Y
S
C
D
Q
E
R
Q
Site 24
S226
R
N
S
E
K
V
Y
S
C
D
Q
E
R
Q
S
Site 25
S233
S
C
D
Q
E
R
Q
S
A
L
E
E
A
Q
Q
Site 26
Y257
E
C
A
P
G
G
L
Y
K
P
V
Q
C
H
Q
Site 27
T283
T
G
R
P
L
P
G
T
S
T
R
Y
V
M
P
Site 28
S284
G
R
P
L
P
G
T
S
T
R
Y
V
M
P
S
Site 29
T285
R
P
L
P
G
T
S
T
R
Y
V
M
P
S
C
Site 30
Y287
L
P
G
T
S
T
R
Y
V
M
P
S
C
E
S
Site 31
S291
S
T
R
Y
V
M
P
S
C
E
S
D
A
R
A
Site 32
T300
E
S
D
A
R
A
K
T
T
E
A
D
D
P
F
Site 33
S341
D
M
V
Q
A
I
N
S
A
A
P
T
G
G
G
Site 34
T345
A
I
N
S
A
A
P
T
G
G
G
R
F
S
E
Site 35
S351
P
T
G
G
G
R
F
S
E
P
D
P
S
H
T
Site 36
S356
R
F
S
E
P
D
P
S
H
T
L
E
E
R
V
Site 37
T358
S
E
P
D
P
S
H
T
L
E
E
R
V
V
H
Site 38
Y367
E
E
R
V
V
H
W
Y
F
S
Q
L
D
S
N
Site 39
S369
R
V
V
H
W
Y
F
S
Q
L
D
S
N
S
S
Site 40
S373
W
Y
F
S
Q
L
D
S
N
S
S
N
D
I
N
Site 41
S375
F
S
Q
L
D
S
N
S
S
N
D
I
N
K
R
Site 42
Y390
E
M
K
P
F
K
R
Y
V
K
K
K
A
K
P
Site 43
Y407
C
A
R
R
F
T
D
Y
C
D
L
N
K
D
K
Site 44
S417
L
N
K
D
K
V
I
S
L
P
E
L
K
G
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation