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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAV1
Full Name:
Protein salvador homolog 1
Alias:
45 kDa WW domain protein; Salvador; Salvador 1; SAV; WW45; WWP4
Type:
Mass (Da):
44634
Number AA:
383
UniProt ID:
Q9H4B6
International Prot ID:
IPI00301738
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
L
S
R
K
K
T
K
N
E
V
S
K
P
Site 2
S12
K
K
T
K
N
E
V
S
K
P
A
E
V
Q
G
Site 3
Y21
P
A
E
V
Q
G
K
Y
V
K
K
E
T
S
P
Site 4
T26
G
K
Y
V
K
K
E
T
S
P
L
L
R
N
L
Site 5
S27
K
Y
V
K
K
E
T
S
P
L
L
R
N
L
M
Site 6
S36
L
L
R
N
L
M
P
S
F
I
R
H
G
P
T
Site 7
T48
G
P
T
I
P
R
R
T
D
I
C
L
P
D
S
Site 8
S55
T
D
I
C
L
P
D
S
S
P
N
A
F
S
T
Site 9
S56
D
I
C
L
P
D
S
S
P
N
A
F
S
T
S
Site 10
S61
D
S
S
P
N
A
F
S
T
S
G
D
V
V
S
Site 11
S63
S
P
N
A
F
S
T
S
G
D
V
V
S
R
N
Site 12
S68
S
T
S
G
D
V
V
S
R
N
Q
S
F
L
R
Site 13
S72
D
V
V
S
R
N
Q
S
F
L
R
T
P
I
Q
Site 14
T76
R
N
Q
S
F
L
R
T
P
I
Q
R
T
P
H
Site 15
T81
L
R
T
P
I
Q
R
T
P
H
E
I
M
R
R
Site 16
S90
H
E
I
M
R
R
E
S
N
R
L
S
A
P
S
Site 17
S94
R
R
E
S
N
R
L
S
A
P
S
Y
L
A
R
Site 18
S97
S
N
R
L
S
A
P
S
Y
L
A
R
S
L
A
Site 19
Y98
N
R
L
S
A
P
S
Y
L
A
R
S
L
A
D
Site 20
S102
A
P
S
Y
L
A
R
S
L
A
D
V
P
R
E
Site 21
Y110
L
A
D
V
P
R
E
Y
G
S
S
Q
S
F
V
Site 22
S113
V
P
R
E
Y
G
S
S
Q
S
F
V
T
E
V
Site 23
S115
R
E
Y
G
S
S
Q
S
F
V
T
E
V
S
F
Site 24
S121
Q
S
F
V
T
E
V
S
F
A
V
E
N
G
D
Site 25
S129
F
A
V
E
N
G
D
S
G
S
R
Y
Y
Y
S
Site 26
S131
V
E
N
G
D
S
G
S
R
Y
Y
Y
S
D
N
Site 27
Y133
N
G
D
S
G
S
R
Y
Y
Y
S
D
N
F
F
Site 28
Y134
G
D
S
G
S
R
Y
Y
Y
S
D
N
F
F
D
Site 29
Y135
D
S
G
S
R
Y
Y
Y
S
D
N
F
F
D
G
Site 30
S136
S
G
S
R
Y
Y
Y
S
D
N
F
F
D
G
Q
Site 31
Y156
G
D
R
A
H
E
D
Y
R
Y
Y
E
Y
N
H
Site 32
Y158
R
A
H
E
D
Y
R
Y
Y
E
Y
N
H
D
L
Site 33
Y159
A
H
E
D
Y
R
Y
Y
E
Y
N
H
D
L
F
Site 34
Y161
E
D
Y
R
Y
Y
E
Y
N
H
D
L
F
Q
R
Site 35
S178
Q
N
Q
G
R
H
A
S
G
I
G
R
V
A
A
Site 36
T192
A
T
S
L
G
N
L
T
N
H
G
S
E
D
L
Site 37
S196
G
N
L
T
N
H
G
S
E
D
L
P
L
P
P
Site 38
S206
L
P
L
P
P
G
W
S
V
D
W
T
M
R
G
Site 39
T210
P
G
W
S
V
D
W
T
M
R
G
R
K
Y
Y
Site 40
Y217
T
M
R
G
R
K
Y
Y
I
D
H
N
T
N
T
Site 41
S245
P
G
W
E
R
V
E
S
S
E
F
G
T
Y
Y
Site 42
S246
G
W
E
R
V
E
S
S
E
F
G
T
Y
Y
V
Site 43
T250
V
E
S
S
E
F
G
T
Y
Y
V
D
H
T
N
Site 44
Y251
E
S
S
E
F
G
T
Y
Y
V
D
H
T
N
K
Site 45
Y252
S
S
E
F
G
T
Y
Y
V
D
H
T
N
K
K
Site 46
T256
G
T
Y
Y
V
D
H
T
N
K
K
A
Q
Y
R
Site 47
Y262
H
T
N
K
K
A
Q
Y
R
H
P
C
A
P
S
Site 48
S269
Y
R
H
P
C
A
P
S
V
P
R
Y
D
Q
P
Site 49
Y273
C
A
P
S
V
P
R
Y
D
Q
P
P
P
V
T
Site 50
T280
Y
D
Q
P
P
P
V
T
Y
Q
P
Q
Q
T
E
Site 51
T286
V
T
Y
Q
P
Q
Q
T
E
R
N
Q
S
L
L
Site 52
S291
Q
Q
T
E
R
N
Q
S
L
L
V
P
A
N
P
Site 53
Y311
I
P
D
W
L
Q
V
Y
A
R
A
P
V
K
Y
Site 54
Y318
Y
A
R
A
P
V
K
Y
D
H
I
L
K
W
E
Site 55
T363
A
Y
R
Q
A
L
L
T
E
L
E
N
R
K
Q
Site 56
Y375
R
K
Q
R
Q
Q
W
Y
A
Q
Q
H
G
K
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation