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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRISPLD1
Full Name:
Cysteine-rich secretory protein LCCL domain-containing 1
Alias:
CRISP10; CRLD1; LCRISP1
Type:
Mass (Da):
56888
Number AA:
500
UniProt ID:
Q9H336
International Prot ID:
IPI00027806
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
L
E
K
L
L
E
K
Y
M
D
E
D
G
E
W
Site 2
T58
Q
R
G
K
R
A
I
T
D
N
D
M
Q
S
I
Site 3
S74
D
L
H
N
K
L
R
S
Q
V
Y
P
T
A
S
Site 4
Y77
N
K
L
R
S
Q
V
Y
P
T
A
S
N
M
E
Site 5
Y85
P
T
A
S
N
M
E
Y
M
T
W
D
V
E
L
Site 6
S95
W
D
V
E
L
E
R
S
A
E
S
W
A
E
S
Site 7
S98
E
L
E
R
S
A
E
S
W
A
E
S
C
L
W
Site 8
S102
S
A
E
S
W
A
E
S
C
L
W
E
H
G
P
Site 9
S111
L
W
E
H
G
P
A
S
L
L
P
S
I
G
Q
Site 10
Y127
L
G
A
H
W
G
R
Y
R
P
P
T
F
H
V
Site 11
Y138
T
F
H
V
Q
S
W
Y
D
E
V
K
D
F
S
Site 12
Y146
D
E
V
K
D
F
S
Y
P
Y
E
H
E
C
N
Site 13
Y148
V
K
D
F
S
Y
P
Y
E
H
E
C
N
P
Y
Site 14
S225
Y
K
H
G
R
P
C
S
A
C
P
P
S
F
G
Site 15
S230
P
C
S
A
C
P
P
S
F
G
G
G
C
R
E
Site 16
Y241
G
C
R
E
N
L
C
Y
K
E
G
S
D
R
Y
Site 17
S245
N
L
C
Y
K
E
G
S
D
R
Y
Y
P
P
R
Site 18
Y248
Y
K
E
G
S
D
R
Y
Y
P
P
R
E
E
E
Site 19
Y249
K
E
G
S
D
R
Y
Y
P
P
R
E
E
E
T
Site 20
S264
N
E
I
E
R
Q
Q
S
Q
V
H
D
T
H
V
Site 21
T269
Q
Q
S
Q
V
H
D
T
H
V
R
T
R
S
D
Site 22
S275
D
T
H
V
R
T
R
S
D
D
S
S
R
N
E
Site 23
S278
V
R
T
R
S
D
D
S
S
R
N
E
V
I
S
Site 24
S279
R
T
R
S
D
D
S
S
R
N
E
V
I
S
A
Site 25
S285
S
S
R
N
E
V
I
S
A
Q
Q
M
S
Q
I
Site 26
S294
Q
Q
M
S
Q
I
V
S
C
E
V
R
L
R
D
Site 27
Y311
K
G
T
T
C
N
R
Y
E
C
P
A
G
C
L
Site 28
S327
S
K
A
K
V
I
G
S
V
H
Y
E
M
Q
S
Site 29
Y363
T
R
Q
G
R
K
H
Y
F
I
K
S
N
R
N
Site 30
T374
S
N
R
N
G
I
Q
T
I
G
K
Y
Q
S
A
Site 31
Y378
G
I
Q
T
I
G
K
Y
Q
S
A
N
S
F
T
Site 32
S380
Q
T
I
G
K
Y
Q
S
A
N
S
F
T
V
S
Site 33
S383
G
K
Y
Q
S
A
N
S
F
T
V
S
K
V
T
Site 34
Y429
C
M
Q
A
N
P
H
Y
A
R
V
I
G
T
R
Site 35
S442
T
R
V
Y
S
D
L
S
S
I
C
R
A
A
V
Site 36
T471
M
P
V
D
K
R
K
T
Y
I
A
S
F
Q
N
Site 37
Y472
P
V
D
K
R
K
T
Y
I
A
S
F
Q
N
G
Site 38
S475
K
R
K
T
Y
I
A
S
F
Q
N
G
I
F
S
Site 39
S482
S
F
Q
N
G
I
F
S
E
S
L
Q
N
P
P
Site 40
S484
Q
N
G
I
F
S
E
S
L
Q
N
P
P
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation