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Updated November 2019
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Protein Info
Short Name:
ZFP106
Full Name:
Zinc finger protein 106 homolog
Alias:
SH3BP3; SH3-domain binding protein 3; ZF106; Zfp-106; Zinc finger protein 106; Zinc finger protein 474; ZNF474
Type:
Uncharacterized protein
Mass (Da):
208883
Number AA:
1883
UniProt ID:
Q9H2Y7
International Prot ID:
IPI00782966
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005622
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0008270
GO:0005102
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0007165
GO:0007166
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
V
G
R
I
E
C
P
S
S
P
S
F
P
R
D
Site 2
S11
G
R
I
E
C
P
S
S
P
S
F
P
R
D
I
Site 3
S13
I
E
C
P
S
S
P
S
F
P
R
D
I
S
H
Site 4
S19
P
S
F
P
R
D
I
S
H
E
C
R
V
C
G
Site 5
Y35
T
E
V
G
L
S
A
Y
A
K
H
I
S
G
Q
Site 6
Y66
G
E
E
E
E
E
D
Y
F
D
K
E
L
I
Q
Site 7
S82
I
K
Q
R
K
E
Q
S
R
Q
D
E
P
S
N
Site 8
S88
Q
S
R
Q
D
E
P
S
N
S
N
Q
E
I
N
Site 9
S90
R
Q
D
E
P
S
N
S
N
Q
E
I
N
S
D
Site 10
S96
N
S
N
Q
E
I
N
S
D
D
R
R
P
Q
W
Site 11
Y111
R
R
E
D
R
I
P
Y
Q
D
R
E
S
Y
S
Site 12
Y117
P
Y
Q
D
R
E
S
Y
S
Q
P
A
W
H
H
Site 13
T142
E
K
D
G
F
N
N
T
R
K
N
S
F
P
H
Site 14
S146
F
N
N
T
R
K
N
S
F
P
H
S
L
R
N
Site 15
S150
R
K
N
S
F
P
H
S
L
R
N
G
G
G
P
Site 16
S161
G
G
G
P
R
G
R
S
G
W
H
K
G
V
A
Site 17
S187
N
S
G
G
G
W
L
S
N
S
G
A
V
D
W
Site 18
S203
H
N
G
T
G
R
N
S
S
W
L
S
E
G
T
Site 19
S204
N
G
T
G
R
N
S
S
W
L
S
E
G
T
G
Site 20
S207
G
R
N
S
S
W
L
S
E
G
T
G
G
F
S
Site 21
T210
S
S
W
L
S
E
G
T
G
G
F
S
S
W
H
Site 22
S227
N
S
N
G
N
W
K
S
S
V
R
S
T
N
N
Site 23
S231
N
W
K
S
S
V
R
S
T
N
N
W
N
Y
S
Site 24
T232
W
K
S
S
V
R
S
T
N
N
W
N
Y
S
G
Site 25
Y237
R
S
T
N
N
W
N
Y
S
G
P
G
D
K
F
Site 26
S238
S
T
N
N
W
N
Y
S
G
P
G
D
K
F
Q
Site 27
Y273
K
S
N
K
S
N
K
Y
S
H
D
R
Y
N
W
Site 28
Y278
N
K
Y
S
H
D
R
Y
N
W
Q
R
Q
E
N
Site 29
T293
D
K
L
G
T
V
A
T
Y
R
G
P
S
E
G
Site 30
Y294
K
L
G
T
V
A
T
Y
R
G
P
S
E
G
F
Site 31
S298
V
A
T
Y
R
G
P
S
E
G
F
T
S
D
K
Site 32
T302
R
G
P
S
E
G
F
T
S
D
K
F
P
S
E
Site 33
S303
G
P
S
E
G
F
T
S
D
K
F
P
S
E
G
Site 34
S321
F
N
F
E
Q
L
E
S
Q
T
T
K
Q
A
D
Site 35
T324
E
Q
L
E
S
Q
T
T
K
Q
A
D
T
A
T
Site 36
T329
Q
T
T
K
Q
A
D
T
A
T
S
K
V
S
G
Site 37
T331
T
K
Q
A
D
T
A
T
S
K
V
S
G
K
N
Site 38
S332
K
Q
A
D
T
A
T
S
K
V
S
G
K
N
G
Site 39
S340
K
V
S
G
K
N
G
S
A
A
R
E
K
P
R
Site 40
T350
R
E
K
P
R
R
W
T
P
Y
P
S
Q
K
T
Site 41
Y352
K
P
R
R
W
T
P
Y
P
S
Q
K
T
L
D
Site 42
S354
R
R
W
T
P
Y
P
S
Q
K
T
L
D
L
Q
Site 43
T357
T
P
Y
P
S
Q
K
T
L
D
L
Q
S
G
L
Site 44
T368
Q
S
G
L
K
D
I
T
G
N
K
S
E
M
I
Site 45
S372
K
D
I
T
G
N
K
S
E
M
I
E
K
P
L
Site 46
T387
F
D
F
S
L
I
T
T
G
I
Q
E
P
Q
T
Site 47
T394
T
G
I
Q
E
P
Q
T
D
E
T
R
N
S
P
Site 48
T397
Q
E
P
Q
T
D
E
T
R
N
S
P
T
Q
K
Site 49
S400
Q
T
D
E
T
R
N
S
P
T
Q
K
T
Q
K
Site 50
S413
Q
K
E
I
H
T
G
S
L
N
H
K
A
S
S
Site 51
S419
G
S
L
N
H
K
A
S
S
D
S
A
A
S
F
Site 52
S420
S
L
N
H
K
A
S
S
D
S
A
A
S
F
E
Site 53
S422
N
H
K
A
S
S
D
S
A
A
S
F
E
V
V
Site 54
S425
A
S
S
D
S
A
A
S
F
E
V
V
R
Q
C
Site 55
T443
E
K
P
E
Q
E
H
T
P
N
K
M
P
S
L
Site 56
S449
H
T
P
N
K
M
P
S
L
K
S
P
L
L
P
Site 57
S452
N
K
M
P
S
L
K
S
P
L
L
P
C
P
A
Site 58
T460
P
L
L
P
C
P
A
T
K
S
L
S
Q
K
Q
Site 59
S462
L
P
C
P
A
T
K
S
L
S
Q
K
Q
D
P
Site 60
S464
C
P
A
T
K
S
L
S
Q
K
Q
D
P
K
N
Site 61
T478
N
I
S
K
N
T
K
T
N
F
F
S
P
G
E
Site 62
S482
N
T
K
T
N
F
F
S
P
G
E
H
S
N
P
Site 63
S487
F
F
S
P
G
E
H
S
N
P
S
N
K
P
T
Site 64
T494
S
N
P
S
N
K
P
T
V
E
D
N
H
G
P
Site 65
Y502
V
E
D
N
H
G
P
Y
I
S
K
L
R
S
S
Site 66
S504
D
N
H
G
P
Y
I
S
K
L
R
S
S
C
P
Site 67
S508
P
Y
I
S
K
L
R
S
S
C
P
H
V
L
K
Site 68
S509
Y
I
S
K
L
R
S
S
C
P
H
V
L
K
G
Site 69
S519
H
V
L
K
G
N
K
S
T
F
G
S
Q
K
Q
Site 70
T520
V
L
K
G
N
K
S
T
F
G
S
Q
K
Q
S
Site 71
S523
G
N
K
S
T
F
G
S
Q
K
Q
S
G
D
N
Site 72
S527
T
F
G
S
Q
K
Q
S
G
D
N
L
N
D
T
Site 73
T534
S
G
D
N
L
N
D
T
L
R
K
A
K
E
V
Site 74
S547
E
V
L
Q
C
H
E
S
L
Q
N
P
L
L
S
Site 75
S554
S
L
Q
N
P
L
L
S
T
S
K
S
T
R
N
Site 76
S556
Q
N
P
L
L
S
T
S
K
S
T
R
N
Y
A
Site 77
S558
P
L
L
S
T
S
K
S
T
R
N
Y
A
K
A
Site 78
Y562
T
S
K
S
T
R
N
Y
A
K
A
S
R
N
V
Site 79
S572
A
S
R
N
V
E
E
S
E
K
G
S
L
K
I
Site 80
S576
V
E
E
S
E
K
G
S
L
K
I
E
F
Q
V
Site 81
S590
V
H
A
L
E
D
E
S
D
G
E
T
S
D
T
Site 82
T594
E
D
E
S
D
G
E
T
S
D
T
E
K
H
G
Site 83
S595
D
E
S
D
G
E
T
S
D
T
E
K
H
G
T
Site 84
T597
S
D
G
E
T
S
D
T
E
K
H
G
T
K
I
Site 85
T602
S
D
T
E
K
H
G
T
K
I
G
T
L
G
S
Site 86
S616
S
A
T
T
E
L
L
S
G
S
T
R
T
A
D
Site 87
S618
T
T
E
L
L
S
G
S
T
R
T
A
D
E
K
Site 88
T634
E
D
D
R
I
L
K
T
S
R
E
L
S
T
S
Site 89
S635
D
D
R
I
L
K
T
S
R
E
L
S
T
S
P
Site 90
S639
L
K
T
S
R
E
L
S
T
S
P
C
N
P
I
Site 91
T640
K
T
S
R
E
L
S
T
S
P
C
N
P
I
V
Site 92
S641
T
S
R
E
L
S
T
S
P
C
N
P
I
V
R
Site 93
S652
P
I
V
R
Q
K
E
S
E
L
Q
M
T
S
A
Site 94
T657
K
E
S
E
L
Q
M
T
S
A
A
S
P
H
P
Site 95
S658
E
S
E
L
Q
M
T
S
A
A
S
P
H
P
G
Site 96
S661
L
Q
M
T
S
A
A
S
P
H
P
G
L
L
L
Site 97
S682
E
D
A
Q
V
D
D
S
I
K
S
H
V
S
Y
Site 98
Y689
S
I
K
S
H
V
S
Y
E
T
E
G
F
E
S
Site 99
S698
T
E
G
F
E
S
A
S
L
D
A
E
L
Q
K
Site 100
S706
L
D
A
E
L
Q
K
S
D
I
S
Q
P
S
G
Site 101
S709
E
L
Q
K
S
D
I
S
Q
P
S
G
P
L
L
Site 102
S712
K
S
D
I
S
Q
P
S
G
P
L
L
P
E
L
Site 103
S727
S
K
L
G
F
P
A
S
L
Q
R
D
L
T
R
Site 104
T733
A
S
L
Q
R
D
L
T
R
H
I
S
L
K
S
Site 105
S737
R
D
L
T
R
H
I
S
L
K
S
K
T
G
V
Site 106
S740
T
R
H
I
S
L
K
S
K
T
G
V
H
L
P
Site 107
T742
H
I
S
L
K
S
K
T
G
V
H
L
P
E
P
Site 108
S753
L
P
E
P
N
L
N
S
A
R
R
I
R
N
I
Site 109
S761
A
R
R
I
R
N
I
S
G
H
R
K
S
E
T
Site 110
S766
N
I
S
G
H
R
K
S
E
T
E
K
E
S
G
Site 111
T768
S
G
H
R
K
S
E
T
E
K
E
S
G
L
K
Site 112
T777
K
E
S
G
L
K
P
T
L
R
Q
I
L
N
A
Site 113
S785
L
R
Q
I
L
N
A
S
R
R
N
V
N
W
E
Site 114
S836
L
D
G
E
P
D
L
S
S
L
E
G
F
Q
W
Site 115
S837
D
G
E
P
D
L
S
S
L
E
G
F
Q
W
E
Site 116
S847
G
F
Q
W
E
G
V
S
I
S
S
S
P
G
L
Site 117
S849
Q
W
E
G
V
S
I
S
S
S
P
G
L
A
R
Site 118
S851
E
G
V
S
I
S
S
S
P
G
L
A
R
K
R
Site 119
S859
P
G
L
A
R
K
R
S
L
S
E
S
S
V
I
Site 120
S861
L
A
R
K
R
S
L
S
E
S
S
V
I
M
D
Site 121
S863
R
K
R
S
L
S
E
S
S
V
I
M
D
R
A
Site 122
S864
K
R
S
L
S
E
S
S
V
I
M
D
R
A
P
Site 123
Y874
M
D
R
A
P
S
V
Y
S
F
F
S
E
E
G
Site 124
S875
D
R
A
P
S
V
Y
S
F
F
S
E
E
G
T
Site 125
S878
P
S
V
Y
S
F
F
S
E
E
G
T
G
K
E
Site 126
T882
S
F
F
S
E
E
G
T
G
K
E
N
E
P
Q
Site 127
S893
N
E
P
Q
Q
M
V
S
P
S
N
S
L
R
A
Site 128
S895
P
Q
Q
M
V
S
P
S
N
S
L
R
A
G
Q
Site 129
S897
Q
M
V
S
P
S
N
S
L
R
A
G
Q
S
Q
Site 130
S903
N
S
L
R
A
G
Q
S
Q
K
A
T
M
H
L
Site 131
T907
A
G
Q
S
Q
K
A
T
M
H
L
K
Q
E
V
Site 132
T915
M
H
L
K
Q
E
V
T
P
R
A
A
S
L
R
Site 133
S920
E
V
T
P
R
A
A
S
L
R
T
G
E
R
A
Site 134
T932
E
R
A
E
N
V
A
T
Q
R
R
H
S
A
Q
Site 135
S937
V
A
T
Q
R
R
H
S
A
Q
L
S
S
D
H
Site 136
S941
R
R
H
S
A
Q
L
S
S
D
H
I
I
P
L
Site 137
S942
R
H
S
A
Q
L
S
S
D
H
I
I
P
L
M
Site 138
S957
H
L
A
K
D
L
N
S
Q
E
R
S
I
P
P
Site 139
S961
D
L
N
S
Q
E
R
S
I
P
P
S
E
N
Q
Site 140
S965
Q
E
R
S
I
P
P
S
E
N
Q
N
S
Q
E
Site 141
S970
P
P
S
E
N
Q
N
S
Q
E
S
N
G
E
G
Site 142
S981
N
G
E
G
N
C
L
S
S
S
A
S
S
A
L
Site 143
S982
G
E
G
N
C
L
S
S
S
A
S
S
A
L
A
Site 144
T998
S
S
L
A
D
A
A
T
D
S
S
C
T
S
G
Site 145
S1000
L
A
D
A
A
T
D
S
S
C
T
S
G
A
E
Site 146
S1001
A
D
A
A
T
D
S
S
C
T
S
G
A
E
Q
Site 147
S1004
A
T
D
S
S
C
T
S
G
A
E
Q
N
D
G
Site 148
S1013
A
E
Q
N
D
G
Q
S
I
R
K
K
R
R
A
Site 149
T1021
I
R
K
K
R
R
A
T
G
D
G
S
S
P
E
Site 150
S1025
R
R
A
T
G
D
G
S
S
P
E
L
P
S
L
Site 151
S1026
R
A
T
G
D
G
S
S
P
E
L
P
S
L
E
Site 152
S1031
G
S
S
P
E
L
P
S
L
E
R
K
N
K
R
Site 153
S1048
I
K
G
K
K
E
R
S
Q
V
D
Q
L
L
N
Site 154
S1057
V
D
Q
L
L
N
I
S
L
R
E
E
E
L
S
Site 155
S1064
S
L
R
E
E
E
L
S
K
S
L
Q
C
M
D
Site 156
S1066
R
E
E
E
L
S
K
S
L
Q
C
M
D
N
N
Site 157
T1083
Q
A
R
A
A
L
Q
T
A
Y
V
E
V
Q
R
Site 158
T1107
M
E
M
S
A
L
R
T
H
R
I
Q
I
L
Q
Site 159
T1119
I
L
Q
G
L
Q
E
T
Y
E
P
S
E
H
P
Site 160
S1132
H
P
D
Q
V
P
C
S
L
T
R
E
R
R
N
Site 161
T1134
D
Q
V
P
C
S
L
T
R
E
R
R
N
S
R
Site 162
S1140
L
T
R
E
R
R
N
S
R
S
Q
T
S
I
D
Site 163
S1142
R
E
R
R
N
S
R
S
Q
T
S
I
D
A
A
Site 164
T1144
R
R
N
S
R
S
Q
T
S
I
D
A
A
L
L
Site 165
S1164
P
L
F
L
E
P
P
S
S
H
V
S
P
S
P
Site 166
S1165
L
F
L
E
P
P
S
S
H
V
S
P
S
P
T
Site 167
S1168
E
P
P
S
S
H
V
S
P
S
P
T
G
A
S
Site 168
S1170
P
S
S
H
V
S
P
S
P
T
G
A
S
L
Q
Site 169
T1172
S
H
V
S
P
S
P
T
G
A
S
L
Q
I
T
Site 170
S1175
S
P
S
P
T
G
A
S
L
Q
I
T
T
S
P
Site 171
T1179
T
G
A
S
L
Q
I
T
T
S
P
T
F
Q
T
Site 172
S1181
A
S
L
Q
I
T
T
S
P
T
F
Q
T
H
G
Site 173
T1183
L
Q
I
T
T
S
P
T
F
Q
T
H
G
S
V
Site 174
S1189
P
T
F
Q
T
H
G
S
V
P
A
P
D
S
S
Site 175
S1195
G
S
V
P
A
P
D
S
S
V
Q
I
K
Q
E
Site 176
S1196
S
V
P
A
P
D
S
S
V
Q
I
K
Q
E
P
Site 177
S1205
Q
I
K
Q
E
P
M
S
P
E
Q
D
E
N
V
Site 178
S1218
N
V
N
A
V
P
P
S
S
A
C
N
V
S
K
Site 179
S1219
V
N
A
V
P
P
S
S
A
C
N
V
S
K
E
Site 180
S1235
L
E
A
N
R
E
I
S
D
S
C
P
V
Y
P
Site 181
S1237
A
N
R
E
I
S
D
S
C
P
V
Y
P
V
I
Site 182
S1249
P
V
I
T
A
R
L
S
L
P
E
S
T
E
S
Site 183
S1253
A
R
L
S
L
P
E
S
T
E
S
F
H
E
P
Site 184
S1256
S
L
P
E
S
T
E
S
F
H
E
P
S
Q
E
Site 185
S1261
T
E
S
F
H
E
P
S
Q
E
L
K
F
S
V
Site 186
S1267
P
S
Q
E
L
K
F
S
V
E
Q
R
N
T
R
Site 187
T1273
F
S
V
E
Q
R
N
T
R
N
R
E
N
S
P
Site 188
S1279
N
T
R
N
R
E
N
S
P
S
S
Q
S
A
G
Site 189
S1281
R
N
R
E
N
S
P
S
S
Q
S
A
G
L
S
Site 190
S1282
N
R
E
N
S
P
S
S
Q
S
A
G
L
S
S
Site 191
S1284
E
N
S
P
S
S
Q
S
A
G
L
S
S
I
N
Site 192
S1288
S
S
Q
S
A
G
L
S
S
I
N
K
E
G
E
Site 193
S1289
S
Q
S
A
G
L
S
S
I
N
K
E
G
E
E
Site 194
S1302
E
E
P
T
K
G
N
S
G
S
E
A
C
T
S
Site 195
S1304
P
T
K
G
N
S
G
S
E
A
C
T
S
S
F
Site 196
T1308
N
S
G
S
E
A
C
T
S
S
F
L
R
L
S
Site 197
S1309
S
G
S
E
A
C
T
S
S
F
L
R
L
S
F
Site 198
S1315
T
S
S
F
L
R
L
S
F
A
S
E
T
P
L
Site 199
S1318
F
L
R
L
S
F
A
S
E
T
P
L
E
K
E
Site 200
T1320
R
L
S
F
A
S
E
T
P
L
E
K
E
P
H
Site 201
S1328
P
L
E
K
E
P
H
S
P
A
D
Q
P
E
Q
Site 202
T1342
Q
Q
A
E
S
T
L
T
S
A
E
T
R
G
S
Site 203
S1343
Q
A
E
S
T
L
T
S
A
E
T
R
G
S
K
Site 204
T1346
S
T
L
T
S
A
E
T
R
G
S
K
K
K
K
Site 205
S1349
T
S
A
E
T
R
G
S
K
K
K
K
K
L
R
Site 206
S1360
K
K
L
R
K
K
K
S
L
R
A
A
H
V
P
Site 207
S1370
A
A
H
V
P
E
N
S
D
T
E
Q
D
V
L
Site 208
T1372
H
V
P
E
N
S
D
T
E
Q
D
V
L
T
V
Site 209
T1378
D
T
E
Q
D
V
L
T
V
K
P
V
R
K
V
Site 210
T1397
L
I
K
G
G
K
V
T
T
S
T
W
E
D
S
Site 211
T1398
I
K
G
G
K
V
T
T
S
T
W
E
D
S
R
Site 212
S1399
K
G
G
K
V
T
T
S
T
W
E
D
S
R
T
Site 213
T1400
G
G
K
V
T
T
S
T
W
E
D
S
R
T
G
Site 214
S1404
T
T
S
T
W
E
D
S
R
T
G
R
E
Q
E
Site 215
T1406
S
T
W
E
D
S
R
T
G
R
E
Q
E
S
V
Site 216
S1412
R
T
G
R
E
Q
E
S
V
R
D
E
P
D
S
Site 217
S1419
S
V
R
D
E
P
D
S
D
S
S
L
E
V
L
Site 218
S1421
R
D
E
P
D
S
D
S
S
L
E
V
L
E
I
Site 219
S1422
D
E
P
D
S
D
S
S
L
E
V
L
E
I
P
Site 220
S1440
L
E
V
V
A
I
D
S
S
E
S
G
E
E
K
Site 221
S1441
E
V
V
A
I
D
S
S
E
S
G
E
E
K
P
Site 222
S1450
S
G
E
E
K
P
D
S
P
S
K
K
D
I
W
Site 223
S1452
E
E
K
P
D
S
P
S
K
K
D
I
W
N
S
Site 224
S1459
S
K
K
D
I
W
N
S
T
E
Q
N
P
L
E
Site 225
S1470
N
P
L
E
T
S
R
S
G
C
D
E
V
S
S
Site 226
S1476
R
S
G
C
D
E
V
S
S
T
S
E
I
G
T
Site 227
S1477
S
G
C
D
E
V
S
S
T
S
E
I
G
T
R
Site 228
T1478
G
C
D
E
V
S
S
T
S
E
I
G
T
R
Y
Site 229
T1483
S
S
T
S
E
I
G
T
R
Y
K
D
G
I
P
Site 230
Y1485
T
S
E
I
G
T
R
Y
K
D
G
I
P
V
S
Site 231
S1492
Y
K
D
G
I
P
V
S
V
A
E
T
Q
T
V
Site 232
S1502
E
T
Q
T
V
I
S
S
I
K
G
S
K
N
S
Site 233
S1506
V
I
S
S
I
K
G
S
K
N
S
S
E
I
S
Site 234
S1509
S
I
K
G
S
K
N
S
S
E
I
S
S
E
P
Site 235
S1510
I
K
G
S
K
N
S
S
E
I
S
S
E
P
G
Site 236
S1513
S
K
N
S
S
E
I
S
S
E
P
G
D
D
D
Site 237
S1514
K
N
S
S
E
I
S
S
E
P
G
D
D
D
E
Site 238
T1523
P
G
D
D
D
E
P
T
E
G
S
F
E
G
H
Site 239
S1526
D
D
E
P
T
E
G
S
F
E
G
H
Q
A
A
Site 240
Y1545
Q
I
F
G
N
L
L
Y
T
C
S
A
D
K
T
Site 241
S1548
G
N
L
L
Y
T
C
S
A
D
K
T
V
R
V
Site 242
T1552
Y
T
C
S
A
D
K
T
V
R
V
Y
N
L
V
Site 243
Y1556
A
D
K
T
V
R
V
Y
N
L
V
S
R
K
C
Site 244
Y1590
S
G
K
N
A
A
L
Y
T
G
S
S
D
H
T
Site 245
S1594
A
A
L
Y
T
G
S
S
D
H
T
I
R
C
Y
Site 246
T1597
Y
T
G
S
S
D
H
T
I
R
C
Y
N
V
K
Site 247
Y1601
S
D
H
T
I
R
C
Y
N
V
K
S
R
E
C
Site 248
Y1629
H
S
R
W
R
I
L
Y
A
G
L
A
N
G
T
Site 249
T1636
Y
A
G
L
A
N
G
T
V
V
T
F
N
I
K
Site 250
T1639
L
A
N
G
T
V
V
T
F
N
I
K
N
N
K
Site 251
S1660
C
H
G
P
R
A
V
S
C
L
A
T
A
Q
E
Site 252
T1664
R
A
V
S
C
L
A
T
A
Q
E
G
A
R
K
Site 253
T1681
V
V
G
S
Y
D
C
T
I
S
V
R
D
A
R
Site 254
S1683
G
S
Y
D
C
T
I
S
V
R
D
A
R
N
G
Site 255
T1695
R
N
G
L
L
L
R
T
L
E
G
H
S
K
T
Site 256
S1717
N
D
L
V
F
S
G
S
S
D
Q
S
V
H
A
Site 257
S1721
F
S
G
S
S
D
Q
S
V
H
A
H
N
I
H
Site 258
Y1736
T
G
E
L
V
R
I
Y
K
G
H
N
H
A
V
Site 259
T1744
K
G
H
N
H
A
V
T
V
V
N
I
L
G
K
Site 260
Y1765
L
D
K
F
V
R
V
Y
E
L
Q
S
H
D
R
Site 261
S1769
V
R
V
Y
E
L
Q
S
H
D
R
L
Q
V
Y
Site 262
Y1776
S
H
D
R
L
Q
V
Y
G
G
H
K
D
M
I
Site 263
T1836
H
L
K
Q
H
L
L
T
D
H
T
N
P
N
F
Site 264
T1839
Q
H
L
L
T
D
H
T
N
P
N
F
Q
T
L
Site 265
S1863
F
F
T
A
R
K
G
S
K
Q
D
A
A
G
H
Site 266
S1879
E
R
H
A
E
D
D
S
K
I
D
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation