KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CHRD
Full Name:
Chordin
Alias:
Type:
Mass (Da):
102032
Number AA:
955
UniProt ID:
Q9H2X0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T63
K
V
Y
A
L
D
E
T
W
H
P
D
L
G
E
Site 2
T91
A
P
Q
W
G
R
R
T
R
G
P
G
R
V
S
Site 3
S98
T
R
G
P
G
R
V
S
C
K
N
I
K
P
E
Site 4
T108
N
I
K
P
E
C
P
T
P
A
C
G
Q
P
R
Site 5
S131
T
C
P
Q
E
R
S
S
S
E
R
Q
P
S
G
Site 6
S132
C
P
Q
E
R
S
S
S
E
R
Q
P
S
G
L
Site 7
S137
S
S
S
E
R
Q
P
S
G
L
S
F
E
Y
P
Site 8
S140
E
R
Q
P
S
G
L
S
F
E
Y
P
R
D
P
Site 9
Y143
P
S
G
L
S
F
E
Y
P
R
D
P
E
H
R
Site 10
S151
P
R
D
P
E
H
R
S
Y
S
D
R
G
E
P
Site 11
Y152
R
D
P
E
H
R
S
Y
S
D
R
G
E
P
G
Site 12
S153
D
P
E
H
R
S
Y
S
D
R
G
E
P
G
A
Site 13
T170
R
A
R
G
D
G
H
T
D
F
V
A
L
L
T
Site 14
S181
A
L
L
T
G
P
R
S
Q
A
V
A
R
A
R
Site 15
S195
R
V
S
L
L
R
S
S
L
R
F
S
I
S
Y
Site 16
S199
L
R
S
S
L
R
F
S
I
S
Y
R
R
L
D
Site 17
S201
S
S
L
R
F
S
I
S
Y
R
R
L
D
R
P
Site 18
Y202
S
L
R
F
S
I
S
Y
R
R
L
D
R
P
T
Site 19
T209
Y
R
R
L
D
R
P
T
R
I
R
F
S
D
S
Site 20
S214
R
P
T
R
I
R
F
S
D
S
N
G
S
V
L
Site 21
S216
T
R
I
R
F
S
D
S
N
G
S
V
L
F
E
Site 22
S219
R
F
S
D
S
N
G
S
V
L
F
E
H
P
A
Site 23
S245
W
R
A
V
P
R
L
S
L
R
L
L
R
A
E
Site 24
T288
E
T
F
S
A
I
L
T
L
E
G
P
P
Q
Q
Site 25
S306
G
I
T
L
L
T
L
S
D
T
E
D
S
L
H
Site 26
S326
R
G
L
L
E
P
R
S
G
G
L
T
Q
V
P
Site 27
T330
E
P
R
S
G
G
L
T
Q
V
P
L
R
L
Q
Site 28
S353
R
E
L
Q
A
N
V
S
A
Q
E
P
G
F
A
Site 29
S394
G
R
P
G
L
R
I
S
G
H
I
A
A
R
K
Site 30
T454
S
S
E
V
V
A
M
T
L
E
T
K
P
Q
R
Site 31
T466
P
Q
R
R
D
Q
R
T
V
L
C
H
M
A
G
Site 32
Y524
G
H
V
A
A
L
P
Y
C
G
H
S
A
R
H
Site 33
T533
G
H
S
A
R
H
D
T
L
P
V
P
L
A
G
Site 34
T592
H
L
L
G
P
P
G
T
P
G
P
R
R
L
L
Site 35
Y603
R
R
L
L
K
G
F
Y
G
S
E
A
Q
G
V
Site 36
T632
G
M
A
S
L
M
I
T
T
K
G
S
P
R
G
Site 37
S636
L
M
I
T
T
K
G
S
P
R
G
E
L
R
G
Site 38
T704
G
R
P
R
D
P
N
T
C
F
F
E
G
Q
Q
Site 39
Y722
G
A
R
W
A
P
N
Y
D
P
L
C
S
L
C
Site 40
S777
D
L
P
G
L
P
R
S
R
D
P
G
E
G
C
Site 41
Y785
R
D
P
G
E
G
C
Y
F
D
G
D
R
S
W
Site 42
S884
Q
W
F
P
E
S
Q
S
W
H
P
S
V
P
P
Site 43
S888
E
S
Q
S
W
H
P
S
V
P
P
F
G
E
M
Site 44
S915
H
C
E
R
D
D
C
S
L
P
L
S
C
G
S
Site 45
S919
D
D
C
S
L
P
L
S
C
G
S
G
K
E
S
Site 46
S922
S
L
P
L
S
C
G
S
G
K
E
S
R
C
C
Site 47
S926
S
C
G
S
G
K
E
S
R
C
C
S
R
C
T
Site 48
S930
G
K
E
S
R
C
C
S
R
C
T
A
H
R
R
Site 49
T933
S
R
C
C
S
R
C
T
A
H
R
R
P
A
P
Site 50
T942
H
R
R
P
A
P
E
T
R
T
D
P
E
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation