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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSPYL2
Full Name:
Testis-specific Y-encoded-like protein 2
Alias:
CDA1; cell division autoantigen 1; CINAP; CTCL; cutaneous T-cell lymphoma-associated tumor antigen se20-4; DENTT; differentially expressed nucleolar TGF-beta1 target; HRIHFB2216; SE20-4; TSPY-like 2; TSYL2
Type:
Mass (Da):
79435
Number AA:
693
UniProt ID:
Q9H2G4
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0000182
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0016568
GO:0008156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
E
G
P
P
A
K
T
R
R
L
S
S
S
E
Site 2
S16
P
A
K
T
R
R
L
S
S
S
E
S
P
Q
R
Site 3
S17
A
K
T
R
R
L
S
S
S
E
S
P
Q
R
D
Site 4
S18
K
T
R
R
L
S
S
S
E
S
P
Q
R
D
P
Site 5
S20
R
R
L
S
S
S
E
S
P
Q
R
D
P
P
P
Site 6
T52
R
P
R
L
Q
E
E
T
E
A
A
Q
V
L
A
Site 7
Y87
E
E
G
G
I
R
A
Y
F
T
L
G
A
E
C
Site 8
S99
A
E
C
P
G
W
D
S
T
I
E
S
G
Y
G
Site 9
T100
E
C
P
G
W
D
S
T
I
E
S
G
Y
G
E
Site 10
S103
G
W
D
S
T
I
E
S
G
Y
G
E
A
P
P
Site 11
T112
Y
G
E
A
P
P
P
T
E
S
L
E
A
L
P
Site 12
S114
E
A
P
P
P
T
E
S
L
E
A
L
P
T
P
Site 13
T120
E
S
L
E
A
L
P
T
P
E
A
S
G
G
S
Site 14
S137
I
D
F
Q
V
V
Q
S
S
S
F
G
G
E
G
Site 15
S150
E
G
A
L
E
T
C
S
A
V
G
W
A
P
Q
Site 16
S164
Q
R
L
V
D
P
K
S
K
E
E
A
I
I
I
Site 17
S182
E
D
E
D
E
R
E
S
M
R
S
S
R
R
R
Site 18
S185
D
E
R
E
S
M
R
S
S
R
R
R
R
R
R
Site 19
S186
E
R
E
S
M
R
S
S
R
R
R
R
R
R
R
Site 20
S204
Q
R
K
V
K
R
E
S
R
E
R
N
A
E
R
Site 21
S214
R
N
A
E
R
M
E
S
I
L
Q
A
L
E
D
Site 22
S277
F
L
N
H
P
R
I
S
I
L
I
N
R
R
D
Site 23
Y290
R
D
E
D
I
F
R
Y
L
T
N
L
Q
V
Q
Site 24
T292
E
D
I
F
R
Y
L
T
N
L
Q
V
Q
D
L
Site 25
S303
V
Q
D
L
R
H
I
S
M
G
Y
K
M
K
L
Site 26
Y306
L
R
H
I
S
M
G
Y
K
M
K
L
Y
F
Q
Site 27
Y311
M
G
Y
K
M
K
L
Y
F
Q
T
N
P
Y
F
Site 28
Y317
L
Y
F
Q
T
N
P
Y
F
T
N
M
V
I
V
Site 29
S332
K
E
F
Q
R
N
R
S
G
R
L
V
S
H
S
Site 30
S337
N
R
S
G
R
L
V
S
H
S
T
P
I
R
W
Site 31
S339
S
G
R
L
V
S
H
S
T
P
I
R
W
H
R
Site 32
T340
G
R
L
V
S
H
S
T
P
I
R
W
H
R
G
Site 33
S366
D
A
S
H
S
F
F
S
W
F
S
N
H
S
L
Site 34
S369
H
S
F
F
S
W
F
S
N
H
S
L
P
E
A
Site 35
S372
F
S
W
F
S
N
H
S
L
P
E
A
D
R
I
Site 36
Y394
L
W
V
N
P
L
R
Y
Y
L
R
E
R
G
S
Site 37
Y395
W
V
N
P
L
R
Y
Y
L
R
E
R
G
S
R
Site 38
S401
Y
Y
L
R
E
R
G
S
R
I
K
R
K
K
Q
Site 39
T415
Q
E
M
K
K
R
K
T
R
G
R
C
E
V
V
Site 40
Y430
I
M
E
D
A
P
D
Y
Y
A
V
E
D
I
F
Site 41
Y431
M
E
D
A
P
D
Y
Y
A
V
E
D
I
F
S
Site 42
S438
Y
A
V
E
D
I
F
S
E
I
S
D
I
D
E
Site 43
S441
E
D
I
F
S
E
I
S
D
I
D
E
T
I
H
Site 44
T446
E
I
S
D
I
D
E
T
I
H
D
I
K
I
S
Site 45
Y461
D
F
M
E
T
T
D
Y
F
E
T
T
D
N
E
Site 46
T505
S
A
D
D
H
E
T
T
D
N
N
E
S
A
D
Site 47
Y539
P
N
N
N
E
N
T
Y
G
N
N
F
F
K
G
Site 48
S558
S
H
G
N
N
Q
D
S
S
D
S
D
N
E
A
Site 49
S559
H
G
N
N
Q
D
S
S
D
S
D
N
E
A
D
Site 50
S561
N
N
Q
D
S
S
D
S
D
N
E
A
D
E
A
Site 51
Y605
D
D
D
R
D
I
E
Y
Y
E
K
V
I
E
D
Site 52
Y606
D
D
R
D
I
E
Y
Y
E
K
V
I
E
D
F
Site 53
Y620
F
D
K
D
Q
A
D
Y
E
D
V
I
E
I
I
Site 54
S628
E
D
V
I
E
I
I
S
D
E
S
V
E
E
E
Site 55
S631
I
E
I
I
S
D
E
S
V
E
E
E
G
I
E
Site 56
Y648
I
Q
Q
D
E
D
I
Y
E
E
G
N
Y
E
E
Site 57
Y653
D
I
Y
E
E
G
N
Y
E
E
E
G
S
E
D
Site 58
S658
G
N
Y
E
E
E
G
S
E
D
V
W
E
E
G
Site 59
S668
V
W
E
E
G
E
D
S
D
D
S
D
L
E
D
Site 60
S671
E
G
E
D
S
D
D
S
D
L
E
D
V
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation