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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDH8A1
Full Name:
Aldehyde dehydrogenase family 8 member A1
Alias:
Aldehyde dehydrogenase 12
Type:
Mass (Da):
53401
Number AA:
487
UniProt ID:
Q9H2A2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
D
G
K
F
L
P
C
S
S
Y
I
D
S
Y
D
Site 2
S23
G
K
F
L
P
C
S
S
Y
I
D
S
Y
D
P
Site 3
S27
P
C
S
S
Y
I
D
S
Y
D
P
S
T
G
E
Site 4
Y28
C
S
S
Y
I
D
S
Y
D
P
S
T
G
E
V
Site 5
S31
Y
I
D
S
Y
D
P
S
T
G
E
V
Y
C
R
Site 6
T32
I
D
S
Y
D
P
S
T
G
E
V
Y
C
R
V
Site 7
Y36
D
P
S
T
G
E
V
Y
C
R
V
P
N
S
G
Site 8
S60
A
A
R
E
A
F
P
S
W
S
S
R
S
P
Q
Site 9
S62
R
E
A
F
P
S
W
S
S
R
S
P
Q
E
R
Site 10
S63
E
A
F
P
S
W
S
S
R
S
P
Q
E
R
S
Site 11
S65
F
P
S
W
S
S
R
S
P
Q
E
R
S
R
V
Site 12
S83
V
A
D
L
L
E
Q
S
L
E
E
F
A
Q
A
Site 13
S92
E
E
F
A
Q
A
E
S
K
D
Q
G
K
T
L
Site 14
S119
Q
N
F
R
F
F
A
S
S
S
L
H
H
T
S
Site 15
S120
N
F
R
F
F
A
S
S
S
L
H
H
T
S
E
Site 16
S121
F
R
F
F
A
S
S
S
L
H
H
T
S
E
C
Site 17
T125
A
S
S
S
L
H
H
T
S
E
C
T
Q
M
D
Site 18
S126
S
S
S
L
H
H
T
S
E
C
T
Q
M
D
H
Site 19
Y139
D
H
L
G
C
M
H
Y
T
V
R
A
P
V
G
Site 20
S228
H
P
E
V
P
L
I
S
F
T
G
S
Q
P
T
Site 21
S232
P
L
I
S
F
T
G
S
Q
P
T
A
E
R
I
Site 22
T240
Q
P
T
A
E
R
I
T
Q
L
S
A
P
H
C
Site 23
S243
A
E
R
I
T
Q
L
S
A
P
H
C
K
K
L
Site 24
S251
A
P
H
C
K
K
L
S
L
E
L
G
G
K
N
Site 25
S279
I
P
A
T
V
R
S
S
F
A
N
Q
G
E
I
Site 26
S298
S
R
I
F
V
Q
K
S
I
Y
S
E
F
L
K
Site 27
T311
L
K
R
F
V
E
A
T
R
K
W
K
V
G
I
Site 28
S340
A
H
L
E
K
V
R
S
Y
V
K
R
A
L
A
Site 29
Y341
H
L
E
K
V
R
S
Y
V
K
R
A
L
A
E
Site 30
S362
G
E
G
V
D
K
L
S
L
P
A
R
N
Q
A
Site 31
T389
K
D
E
S
C
C
M
T
E
E
I
F
G
P
V
Site 32
S404
T
C
V
V
P
F
D
S
E
E
E
V
I
E
R
Site 33
Y417
E
R
A
N
N
V
K
Y
G
L
A
A
T
V
W
Site 34
S462
L
P
F
G
G
M
K
S
S
G
I
G
R
E
G
Site 35
S463
P
F
G
G
M
K
S
S
G
I
G
R
E
G
A
Site 36
S473
G
R
E
G
A
K
D
S
Y
D
F
F
T
E
I
Site 37
Y474
R
E
G
A
K
D
S
Y
D
F
F
T
E
I
K
Site 38
T478
K
D
S
Y
D
F
F
T
E
I
K
T
I
T
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation