PhosphoNET

           
Protein Info 
   
Short Name:  P2RY12
Full Name:  P2Y purinoceptor 12
Alias:  ADP-glucose receptor;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;SP1999
Type: 
Mass (Da):  39439
Number AA:  342
UniProt ID:  Q9H244
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T8MQAVDNLTSAPGNTS
Site 2S15TSAPGNTSLCTRDYK
Site 3S55RIFFQIRSKSNFIIF
Site 4S57FFQIRSKSNFIIFLK
Site 5T66FIIFLKNTVISDLLM
Site 6S69FLKNTVISDLLMILT
Site 7T76SDLLMILTFPFKILS
Site 8Y105QVTSVIFYFTMYISI
Site 9T107TSVIFYFTMYISISF
Site 10Y123GLITIDRYQKTTRPF
Site 11T126TIDRYQKTTRPFKTS
Site 12T127IDRYQKTTRPFKTSN
Site 13T132KTTRPFKTSNPKNLL
Site 14S133TTRPFKTSNPKNLLG
Site 15T163SLPNMILTNRQPRDK
Site 16S176DKNVKKCSFLKSEFG
Site 17Y217TLITKELYRSYVRTR
Site 18S219ITKELYRSYVRTRGV
Site 19Y220TKELYRSYVRTRGVG
Site 20T223LYRSYVRTRGVGKVP
Site 21Y259FHFARIPYTLSQTRD
Site 22T260HFARIPYTLSQTRDV
Site 23S262ARIPYTLSQTRDVFD
Site 24T264IPYTLSQTRDVFDCT
Site 25T271TRDVFDCTAENTLFY
Site 26Y278TAENTLFYVKESTLW
Site 27S311SFRNSLISMLKCPNS
Site 28S318SMLKCPNSATSLSQD
Site 29S321KCPNSATSLSQDNRK
Site 30S323PNSATSLSQDNRKKE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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