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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GBA3
Full Name:
Cytosolic beta-glucosidase
Alias:
Cytosolic beta-glucosidase-like protein 1
Type:
Mass (Da):
53696
Number AA:
469
UniProt ID:
Q9H227
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
W
A
A
A
T
A
A
Y
Q
V
E
G
G
W
D
Site 2
S55
T
G
D
V
A
C
G
S
Y
T
L
W
E
E
D
Site 3
T72
C
I
K
Q
L
G
L
T
H
Y
R
F
S
L
S
Site 4
Y74
K
Q
L
G
L
T
H
Y
R
F
S
L
S
W
S
Site 5
S77
G
L
T
H
Y
R
F
S
L
S
W
S
R
L
L
Site 6
S79
T
H
Y
R
F
S
L
S
W
S
R
L
L
P
D
Site 7
S81
Y
R
F
S
L
S
W
S
R
L
L
P
D
G
T
Site 8
T88
S
R
L
L
P
D
G
T
T
G
F
I
N
Q
K
Site 9
Y99
I
N
Q
K
G
I
D
Y
Y
N
K
I
I
D
D
Site 10
Y100
N
Q
K
G
I
D
Y
Y
N
K
I
I
D
D
L
Site 11
S135
E
D
Q
G
G
W
L
S
E
A
I
I
E
S
F
Site 12
S141
L
S
E
A
I
I
E
S
F
D
K
Y
A
Q
F
Site 13
T162
D
R
V
K
Q
W
I
T
I
N
E
A
N
V
L
Site 14
Y174
N
V
L
S
V
M
S
Y
D
L
G
M
F
P
P
Site 15
S204
L
I
K
A
H
A
R
S
W
H
S
Y
D
S
L
Site 16
S207
A
H
A
R
S
W
H
S
Y
D
S
L
F
R
K
Site 17
Y208
H
A
R
S
W
H
S
Y
D
S
L
F
R
K
K
Site 18
S210
R
S
W
H
S
Y
D
S
L
F
R
K
K
Q
K
Site 19
S236
L
E
P
A
D
P
N
S
V
S
D
Q
E
A
A
Site 20
S238
P
A
D
P
N
S
V
S
D
Q
E
A
A
K
R
Site 21
Y264
P
I
F
I
D
G
D
Y
P
E
V
V
K
S
Q
Site 22
S270
D
Y
P
E
V
V
K
S
Q
I
A
S
M
S
Q
Site 23
S274
V
V
K
S
Q
I
A
S
M
S
Q
K
Q
G
Y
Site 24
S276
K
S
Q
I
A
S
M
S
Q
K
Q
G
Y
P
S
Site 25
Y281
S
M
S
Q
K
Q
G
Y
P
S
S
R
L
P
E
Site 26
S283
S
Q
K
Q
G
Y
P
S
S
R
L
P
E
F
T
Site 27
S284
Q
K
Q
G
Y
P
S
S
R
L
P
E
F
T
E
Site 28
T290
S
S
R
L
P
E
F
T
E
E
E
K
K
M
I
Site 29
Y309
D
F
F
A
V
Q
Y
Y
T
T
R
L
I
K
Y
Site 30
Y316
Y
T
T
R
L
I
K
Y
Q
E
N
K
K
G
E
Site 31
Y359
G
V
C
K
L
L
K
Y
I
K
D
T
Y
N
N
Site 32
T363
L
L
K
Y
I
K
D
T
Y
N
N
P
V
I
Y
Site 33
Y364
L
K
Y
I
K
D
T
Y
N
N
P
V
I
Y
I
Site 34
Y370
T
Y
N
N
P
V
I
Y
I
T
E
N
G
F
P
Site 35
T372
N
N
P
V
I
Y
I
T
E
N
G
F
P
Q
S
Site 36
S379
T
E
N
G
F
P
Q
S
D
P
A
P
L
D
D
Site 37
T387
D
P
A
P
L
D
D
T
Q
R
W
E
Y
F
R
Site 38
Y392
D
D
T
Q
R
W
E
Y
F
R
Q
T
F
Q
E
Site 39
Y429
N
F
E
W
N
Q
G
Y
S
S
R
F
G
L
F
Site 40
Y450
P
A
R
P
R
V
P
Y
T
S
A
K
E
Y
A
Site 41
T451
A
R
P
R
V
P
Y
T
S
A
K
E
Y
A
K
Site 42
S452
R
P
R
V
P
Y
T
S
A
K
E
Y
A
K
I
Site 43
Y456
P
Y
T
S
A
K
E
Y
A
K
I
I
R
N
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation