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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ISCU
Full Name:
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
Alias:
2310020H20Rik; ISU2; MGC74517; NIFU; NifU-like N-terminal domain-containing protein; UPI000007018B
Type:
Uncharacterized protein; Mitochondria
Mass (Da):
17937
Number AA:
167
UniProt ID:
Q9H1K1
International Prot ID:
IPI00022243
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005739
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005506
GO:0051536
GO:0032947
PhosphoSite+
KinaseNET
Biological Process:
GO:0016226
GO:0009399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
R
L
R
R
V
A
S
A
L
L
L
R
S
P
Site 2
S20
A
S
A
L
L
L
R
S
P
R
L
P
A
R
E
Site 3
S29
R
L
P
A
R
E
L
S
A
P
A
R
L
Y
H
Site 4
Y35
L
S
A
P
A
R
L
Y
H
K
K
V
V
D
H
Site 5
Y43
H
K
K
V
V
D
H
Y
E
N
P
R
N
V
G
Site 6
S51
E
N
P
R
N
V
G
S
L
D
K
T
S
K
N
Site 7
T55
N
V
G
S
L
D
K
T
S
K
N
V
G
T
G
Site 8
S56
V
G
S
L
D
K
T
S
K
N
V
G
T
G
L
Site 9
S97
F
K
T
F
G
C
G
S
A
I
A
S
S
S
L
Site 10
S101
G
C
G
S
A
I
A
S
S
S
L
A
T
E
W
Site 11
S102
C
G
S
A
I
A
S
S
S
L
A
T
E
W
V
Site 12
T106
I
A
S
S
S
L
A
T
E
W
V
K
G
K
T
Site 13
T113
T
E
W
V
K
G
K
T
V
E
E
A
L
T
I
Site 14
T119
K
T
V
E
E
A
L
T
I
K
N
T
D
I
A
Site 15
Y153
I
K
A
A
L
A
D
Y
K
L
K
Q
E
P
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation