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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POLR3F
Full Name:
DNA-directed RNA polymerase III subunit RPC6
Alias:
DNA-directed RNA polymerase III 39 kDa polypeptide; polymerase (RNA) III (DNA directed) polypeptide F; RNA polymerase III C39 subunit; RPC39; RPC6
Type:
Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Transcription initiation complex
Mass (Da):
35680
Number AA:
UniProt ID:
Q9H1D9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005666
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003899
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0045089
GO:0032728
GO:0006359
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S68
G
Q
L
D
L
L
R
S
N
T
G
L
L
Y
R
Site 2
T70
L
D
L
L
R
S
N
T
G
L
L
Y
R
I
K
Site 3
Y74
R
S
N
T
G
L
L
Y
R
I
K
D
S
Q
N
Site 4
S79
L
L
Y
R
I
K
D
S
Q
N
A
G
K
M
K
Site 5
S88
N
A
G
K
M
K
G
S
D
N
Q
E
K
L
V
Site 6
Y96
D
N
Q
E
K
L
V
Y
Q
I
I
E
D
A
G
Site 7
S109
A
G
N
K
G
I
W
S
R
D
I
R
Y
K
S
Site 8
Y114
I
W
S
R
D
I
R
Y
K
S
N
L
P
L
T
Site 9
S116
S
R
D
I
R
Y
K
S
N
L
P
L
T
E
I
Site 10
T121
Y
K
S
N
L
P
L
T
E
I
N
K
I
L
K
Site 11
S132
K
I
L
K
N
L
E
S
K
K
L
I
K
A
V
Site 12
S141
K
L
I
K
A
V
K
S
V
A
A
S
K
K
K
Site 13
Y150
A
A
S
K
K
K
V
Y
M
L
Y
N
L
Q
P
Site 14
Y153
K
K
K
V
Y
M
L
Y
N
L
Q
P
D
R
S
Site 15
S160
Y
N
L
Q
P
D
R
S
V
T
G
G
A
W
Y
Site 16
T162
L
Q
P
D
R
S
V
T
G
G
A
W
Y
S
D
Site 17
S168
V
T
G
G
A
W
Y
S
D
Q
D
F
E
S
E
Site 18
T194
F
L
Q
S
K
A
E
T
A
R
E
S
K
Q
N
Site 19
S198
K
A
E
T
A
R
E
S
K
Q
N
P
M
I
Q
Site 20
S208
N
P
M
I
Q
R
N
S
S
F
A
S
S
H
E
Site 21
S209
P
M
I
Q
R
N
S
S
F
A
S
S
H
E
V
Site 22
S212
Q
R
N
S
S
F
A
S
S
H
E
V
W
K
Y
Site 23
S213
R
N
S
S
F
A
S
S
H
E
V
W
K
Y
I
Site 24
Y219
S
S
H
E
V
W
K
Y
I
C
E
L
G
I
S
Site 25
S262
A
K
E
G
T
V
G
S
V
D
G
H
M
K
L
Site 26
S305
E
G
G
E
I
S
P
S
N
C
I
Y
M
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation