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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZCWPW1
Full Name:
Zinc finger CW-type PWWP domain protein 1
Alias:
Type:
Mass (Da):
72007
Number AA:
648
UniProt ID:
Q9H0M4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
F
A
P
P
A
Q
K
S
Y
S
L
L
P
C
S
Site 2
S28
P
P
A
Q
K
S
Y
S
L
L
P
C
S
P
N
Site 3
S33
S
Y
S
L
L
P
C
S
P
N
S
P
K
E
E
Site 4
S36
L
L
P
C
S
P
N
S
P
K
E
E
T
P
G
Site 5
T41
P
N
S
P
K
E
E
T
P
G
I
S
S
P
E
Site 6
S46
E
E
T
P
G
I
S
S
P
E
T
E
A
R
I
Site 7
T49
P
G
I
S
S
P
E
T
E
A
R
I
S
L
P
Site 8
S54
P
E
T
E
A
R
I
S
L
P
K
A
S
L
K
Site 9
S59
R
I
S
L
P
K
A
S
L
K
K
K
E
E
K
Site 10
T68
K
K
K
E
E
K
A
T
M
K
N
V
P
S
R
Site 11
S74
A
T
M
K
N
V
P
S
R
E
Q
E
K
K
R
Site 12
S97
E
K
K
E
K
E
K
S
S
L
T
N
A
E
F
Site 13
T149
S
D
K
E
P
G
I
T
A
S
A
T
D
T
D
Site 14
S151
K
E
P
G
I
T
A
S
A
T
D
T
D
N
A
Site 15
T153
P
G
I
T
A
S
A
T
D
T
D
N
A
N
G
Site 16
T155
I
T
A
S
A
T
D
T
D
N
A
N
G
E
E
Site 17
T166
N
G
E
E
V
P
H
T
Q
E
I
S
V
S
W
Site 18
S170
V
P
H
T
Q
E
I
S
V
S
W
E
G
E
A
Site 19
S172
H
T
Q
E
I
S
V
S
W
E
G
E
A
A
P
Site 20
S184
A
A
P
E
I
R
T
S
K
L
G
Q
P
D
P
Site 21
S194
G
Q
P
D
P
A
P
S
K
K
K
S
N
R
L
Site 22
S198
P
A
P
S
K
K
K
S
N
R
L
T
L
S
K
Site 23
T202
K
K
K
S
N
R
L
T
L
S
K
R
K
K
E
Site 24
S204
K
S
N
R
L
T
L
S
K
R
K
K
E
A
H
Site 25
T217
A
H
E
K
V
E
K
T
Q
G
G
H
E
H
R
Site 26
T232
Q
E
D
R
L
K
K
T
V
Q
D
H
S
Q
I
Site 27
S237
K
K
T
V
Q
D
H
S
Q
I
R
D
Q
Q
K
Site 28
S277
L
C
G
N
I
D
P
S
V
L
P
D
N
W
S
Site 29
Y293
D
Q
N
T
D
V
Q
Y
N
R
C
D
I
P
E
Site 30
T304
D
I
P
E
E
T
W
T
G
L
E
S
D
V
A
Site 31
Y312
G
L
E
S
D
V
A
Y
A
S
Y
I
P
G
S
Site 32
Y344
S
D
P
D
L
G
E
Y
F
L
F
T
S
H
L
Site 33
S349
G
E
Y
F
L
F
T
S
H
L
D
S
L
P
S
Site 34
S353
L
F
T
S
H
L
D
S
L
P
S
K
Y
H
V
Site 35
S356
S
H
L
D
S
L
P
S
K
Y
H
V
T
F
F
Site 36
Y358
L
D
S
L
P
S
K
Y
H
V
T
F
F
G
E
Site 37
T361
L
P
S
K
Y
H
V
T
F
F
G
E
T
V
S
Site 38
S384
L
K
N
F
Q
E
L
S
L
E
L
S
V
M
K
Site 39
S388
Q
E
L
S
L
E
L
S
V
M
K
K
R
R
N
Site 40
S398
K
K
R
R
N
D
C
S
Q
K
L
G
V
A
L
Site 41
S427
V
N
L
F
G
F
W
S
R
F
N
G
S
N
S
Site 42
S444
E
R
K
D
L
Q
L
S
G
L
N
S
P
G
S
Site 43
S448
L
Q
L
S
G
L
N
S
P
G
S
C
L
E
K
Site 44
S451
S
G
L
N
S
P
G
S
C
L
E
K
K
E
K
Site 45
T470
E
K
E
E
G
E
K
T
D
P
I
L
P
I
R
Site 46
T484
R
K
R
V
K
I
Q
T
Q
K
T
K
P
R
G
Site 47
T487
V
K
I
Q
T
Q
K
T
K
P
R
G
L
G
G
Site 48
T498
G
L
G
G
D
A
G
T
A
D
G
R
G
R
T
Site 49
T505
T
A
D
G
R
G
R
T
L
Q
R
K
I
M
K
Site 50
S514
Q
R
K
I
M
K
R
S
L
G
R
K
S
T
A
Site 51
S519
K
R
S
L
G
R
K
S
T
A
P
P
A
P
R
Site 52
T520
R
S
L
G
R
K
S
T
A
P
P
A
P
R
M
Site 53
S536
R
K
E
G
Q
G
N
S
D
S
D
Q
P
G
P
Site 54
S538
E
G
Q
G
N
S
D
S
D
Q
P
G
P
K
K
Site 55
S552
K
K
F
K
A
P
Q
S
K
A
L
A
A
S
F
Site 56
S558
Q
S
K
A
L
A
A
S
F
S
E
G
K
E
V
Site 57
S560
K
A
L
A
A
S
F
S
E
G
K
E
V
R
T
Site 58
T567
S
E
G
K
E
V
R
T
V
P
K
N
L
G
L
Site 59
S583
A
C
K
G
A
C
P
S
S
A
K
E
E
P
R
Site 60
S584
C
K
G
A
C
P
S
S
A
K
E
E
P
R
H
Site 61
T596
P
R
H
R
E
P
L
T
Q
E
A
G
S
V
P
Site 62
S609
V
P
L
E
D
E
A
S
S
D
L
D
L
E
Q
Site 63
S628
V
G
R
E
L
G
Q
S
G
E
L
Q
H
S
N
Site 64
S634
Q
S
G
E
L
Q
H
S
N
S
D
G
E
D
F
Site 65
S636
G
E
L
Q
H
S
N
S
D
G
E
D
F
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation