KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DKFZP434L1717
Full Name:
Transketolase-like protein 2
Alias:
EC 2.2.1.1; FLJ32975; Similar to transketolase; TKTL2; Transketolase-like 2
Type:
Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1; Transferase
Mass (Da):
67877
Number AA:
626
UniProt ID:
Q9H0I9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004802
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
A
K
P
D
V
K
T
V
Q
V
L
R
D
T
Site 2
T19
T
V
Q
V
L
R
D
T
A
N
R
L
R
I
H
Site 3
S27
A
N
R
L
R
I
H
S
I
R
A
T
C
A
S
Site 4
T31
R
I
H
S
I
R
A
T
C
A
S
G
S
G
Q
Site 5
S34
S
I
R
A
T
C
A
S
G
S
G
Q
L
T
S
Site 6
S36
R
A
T
C
A
S
G
S
G
Q
L
T
S
C
C
Site 7
T40
A
S
G
S
G
Q
L
T
S
C
C
S
A
A
E
Site 8
Y59
L
F
F
H
T
M
K
Y
K
Q
T
D
P
E
H
Site 9
S96
E
V
G
D
I
S
E
S
D
L
L
N
L
R
K
Site 10
S106
L
N
L
R
K
L
H
S
D
L
E
R
H
P
T
Site 11
T113
S
D
L
E
R
H
P
T
P
R
L
P
F
V
D
Site 12
Y142
G
M
A
Y
T
G
K
Y
L
D
K
A
S
Y
R
Site 13
Y148
K
Y
L
D
K
A
S
Y
R
V
F
C
L
M
G
Site 14
S159
C
L
M
G
D
G
E
S
S
E
G
S
V
W
E
Site 15
S163
D
G
E
S
S
E
G
S
V
W
E
A
F
A
F
Site 16
Y203
L
E
H
G
A
D
I
Y
Q
N
C
C
E
A
F
Site 17
Y215
E
A
F
G
W
N
T
Y
L
V
D
G
H
D
V
Site 18
S280
A
I
V
K
L
I
E
S
Q
I
Q
T
N
E
N
Site 19
T284
L
I
E
S
Q
I
Q
T
N
E
N
L
I
P
K
Site 20
S292
N
E
N
L
I
P
K
S
P
V
E
D
S
P
Q
Site 21
S297
P
K
S
P
V
E
D
S
P
Q
I
S
I
T
D
Site 22
S301
V
E
D
S
P
Q
I
S
I
T
D
I
K
M
T
Site 23
T303
D
S
P
Q
I
S
I
T
D
I
K
M
T
S
P
Site 24
S309
I
T
D
I
K
M
T
S
P
P
A
Y
K
V
G
Site 25
Y313
K
M
T
S
P
P
A
Y
K
V
G
D
K
I
A
Site 26
Y325
K
I
A
T
Q
K
T
Y
G
L
A
L
A
K
L
Site 27
S343
N
E
R
V
I
V
L
S
G
D
T
M
N
S
T
Site 28
T350
S
G
D
T
M
N
S
T
F
S
E
I
F
R
K
Site 29
S424
I
G
S
H
C
G
V
S
T
G
E
D
G
V
S
Site 30
S431
S
T
G
E
D
G
V
S
Q
M
A
L
E
D
L
Site 31
Y463
I
S
T
E
H
A
I
Y
L
A
A
N
T
K
G
Site 32
T476
K
G
M
C
F
I
R
T
S
Q
P
E
T
A
V
Site 33
T481
I
R
T
S
Q
P
E
T
A
V
I
Y
T
P
Q
Site 34
T486
P
E
T
A
V
I
Y
T
P
Q
E
N
F
E
I
Site 35
S527
L
E
A
A
D
H
L
S
Q
Q
G
I
S
V
R
Site 36
S552
D
A
A
T
I
I
S
S
A
K
A
T
G
G
R
Site 37
T562
A
T
G
G
R
V
I
T
V
E
D
H
Y
R
E
Site 38
Y567
V
I
T
V
E
D
H
Y
R
E
G
G
I
G
E
Site 39
T602
G
V
P
Q
R
G
K
T
S
E
L
L
D
M
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation