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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLC2
Full Name:
Kinesin light chain 2
Alias:
FLJ12387; Kinesin light chain 2; KLC 2
Type:
Motor protein
Mass (Da):
68935
Number AA:
622
UniProt ID:
Q9H0B6
International Prot ID:
IPI00021634
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005871
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0003774
GO:0003777
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
F
P
R
E
E
K
L
S
Q
D
E
I
V
L
G
Site 2
T30
A
V
I
Q
G
L
E
T
L
R
G
E
H
R
A
Site 3
S54
A
G
E
A
E
P
G
S
Q
E
R
C
I
L
L
Site 4
S90
S
H
L
G
A
V
E
S
E
K
Q
K
L
R
A
Site 5
T116
L
R
E
E
L
A
G
T
Q
Q
K
L
Q
R
S
Site 6
S141
K
Q
H
L
L
F
M
S
Q
I
R
K
L
D
E
Site 7
S151
R
K
L
D
E
D
A
S
P
N
E
E
K
G
D
Site 8
T163
K
G
D
V
P
K
D
T
L
D
D
L
F
P
N
Site 9
S175
F
P
N
E
D
E
Q
S
P
A
P
S
P
G
G
Site 10
S179
D
E
Q
S
P
A
P
S
P
G
G
G
D
V
S
Site 11
S186
S
P
G
G
G
D
V
S
G
Q
H
G
G
Y
E
Site 12
Y192
V
S
G
Q
H
G
G
Y
E
I
P
A
R
L
R
Site 13
Y208
L
H
N
L
V
I
Q
Y
A
S
Q
G
R
Y
E
Site 14
Y214
Q
Y
A
S
Q
G
R
Y
E
V
A
V
P
L
C
Site 15
Y256
V
Y
R
D
Q
N
K
Y
K
E
A
A
H
L
L
Site 16
T273
A
L
A
I
R
E
K
T
L
G
K
D
H
P
A
Site 17
Y292
L
N
N
L
A
V
L
Y
G
K
R
G
K
Y
K
Site 18
Y298
L
Y
G
K
R
G
K
Y
K
E
A
E
P
L
C
Site 19
Y345
G
K
A
E
E
V
E
Y
Y
Y
R
R
A
L
E
Site 20
Y346
K
A
E
E
V
E
Y
Y
Y
R
R
A
L
E
I
Site 21
Y347
A
E
E
V
E
Y
Y
Y
R
R
A
L
E
I
Y
Site 22
Y354
Y
R
R
A
L
E
I
Y
A
T
R
L
G
P
D
Site 23
T356
R
A
L
E
I
Y
A
T
R
L
G
P
D
D
P
Site 24
Y376
K
N
N
L
A
S
C
Y
L
K
Q
G
K
Y
Q
Site 25
Y382
C
Y
L
K
Q
G
K
Y
Q
D
A
E
T
L
Y
Site 26
T387
G
K
Y
Q
D
A
E
T
L
Y
K
E
I
L
T
Site 27
Y389
Y
Q
D
A
E
T
L
Y
K
E
I
L
T
R
A
Site 28
S421
H
A
E
E
R
E
E
S
K
D
K
R
R
D
S
Site 29
S428
S
K
D
K
R
R
D
S
A
P
Y
G
E
Y
G
Site 30
Y431
K
R
R
D
S
A
P
Y
G
E
Y
G
S
W
Y
Site 31
Y434
D
S
A
P
Y
G
E
Y
G
S
W
Y
K
A
C
Site 32
S436
A
P
Y
G
E
Y
G
S
W
Y
K
A
C
K
V
Site 33
Y438
Y
G
E
Y
G
S
W
Y
K
A
C
K
V
D
S
Site 34
S445
Y
K
A
C
K
V
D
S
P
T
V
N
T
T
L
Site 35
T447
A
C
K
V
D
S
P
T
V
N
T
T
L
R
S
Site 36
T451
D
S
P
T
V
N
T
T
L
R
S
L
G
A
L
Site 37
Y459
L
R
S
L
G
A
L
Y
R
R
Q
G
K
L
E
Site 38
T470
G
K
L
E
A
A
H
T
L
E
D
C
A
S
R
Site 39
S476
H
T
L
E
D
C
A
S
R
N
R
K
Q
G
L
Site 40
S487
K
Q
G
L
D
P
A
S
Q
T
K
V
V
E
L
Site 41
S499
V
E
L
L
K
D
G
S
G
R
R
G
D
R
R
Site 42
S507
G
R
R
G
D
R
R
S
S
R
D
M
A
G
G
Site 43
S508
R
R
G
D
R
R
S
S
R
D
M
A
G
G
A
Site 44
S519
A
G
G
A
G
P
R
S
E
S
D
L
E
D
V
Site 45
S521
G
A
G
P
R
S
E
S
D
L
E
D
V
G
P
Site 46
S537
A
E
W
N
G
D
G
S
G
S
L
R
R
S
G
Site 47
S539
W
N
G
D
G
S
G
S
L
R
R
S
G
S
F
Site 48
S543
G
S
G
S
L
R
R
S
G
S
F
G
K
L
R
Site 49
S545
G
S
L
R
R
S
G
S
F
G
K
L
R
D
A
Site 50
S556
L
R
D
A
L
R
R
S
S
E
M
L
V
K
K
Site 51
S557
R
D
A
L
R
R
S
S
E
M
L
V
K
K
L
Site 52
T568
V
K
K
L
Q
G
G
T
P
Q
E
P
P
N
P
Site 53
S581
N
P
R
M
K
R
A
S
S
L
N
F
L
N
K
Site 54
S582
P
R
M
K
R
A
S
S
L
N
F
L
N
K
S
Site 55
S589
S
L
N
F
L
N
K
S
V
E
E
P
T
Q
P
Site 56
S602
Q
P
G
G
T
G
L
S
D
S
R
T
L
S
S
Site 57
S604
G
G
T
G
L
S
D
S
R
T
L
S
S
S
S
Site 58
T606
T
G
L
S
D
S
R
T
L
S
S
S
S
M
D
Site 59
S608
L
S
D
S
R
T
L
S
S
S
S
M
D
L
S
Site 60
S609
S
D
S
R
T
L
S
S
S
S
M
D
L
S
R
Site 61
S610
D
S
R
T
L
S
S
S
S
M
D
L
S
R
R
Site 62
S611
S
R
T
L
S
S
S
S
M
D
L
S
R
R
S
Site 63
S615
S
S
S
S
M
D
L
S
R
R
S
S
L
V
G
Site 64
S618
S
M
D
L
S
R
R
S
S
L
V
G
_
_
_
Site 65
S619
M
D
L
S
R
R
S
S
L
V
G
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation