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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAIP1
Full Name:
Polyadenylate-binding protein-interacting protein 1
Alias:
PABC1-interacting 1; PAIP-1; poly (A) binding protein interacting protein 1; polyadenylate-binding protein-interacting 1
Type:
Translation
Mass (Da):
53525
Number AA:
479
UniProt ID:
Q9H074
International Prot ID:
IPI00021466
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0008494
PhosphoSite+
KinaseNET
Biological Process:
GO:0048255
GO:0006417
GO:0006413
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
P
G
A
G
R
G
R
S
R
G
L
G
R
G
G
Site 2
T64
P
P
L
R
Q
P
R
T
T
P
P
P
G
A
Q
Site 3
T65
P
L
R
Q
P
R
T
T
P
P
P
G
A
Q
C
Site 4
S77
A
Q
C
E
V
P
A
S
P
Q
R
P
S
R
P
Site 5
S82
P
A
S
P
Q
R
P
S
R
P
G
A
L
P
E
Site 6
S99
R
P
L
R
A
P
P
S
S
Q
D
K
I
P
Q
Site 7
S100
P
L
R
A
P
P
S
S
Q
D
K
I
P
Q
Q
Site 8
Y136
S
V
N
A
P
E
F
Y
P
S
G
Y
S
S
S
Site 9
S138
N
A
P
E
F
Y
P
S
G
Y
S
S
S
Y
T
Site 10
S141
E
F
Y
P
S
G
Y
S
S
S
Y
T
E
S
Y
Site 11
S142
F
Y
P
S
G
Y
S
S
S
Y
T
E
S
Y
E
Site 12
S143
Y
P
S
G
Y
S
S
S
Y
T
E
S
Y
E
D
Site 13
T145
S
G
Y
S
S
S
Y
T
E
S
Y
E
D
G
C
Site 14
S147
Y
S
S
S
Y
T
E
S
Y
E
D
G
C
E
D
Site 15
Y148
S
S
S
Y
T
E
S
Y
E
D
G
C
E
D
Y
Site 16
Y155
Y
E
D
G
C
E
D
Y
P
T
L
S
E
Y
V
Site 17
T157
D
G
C
E
D
Y
P
T
L
S
E
Y
V
Q
D
Site 18
Y161
D
Y
P
T
L
S
E
Y
V
Q
D
F
L
N
H
Site 19
T170
Q
D
F
L
N
H
L
T
E
Q
P
G
S
F
E
Site 20
S175
H
L
T
E
Q
P
G
S
F
E
T
E
I
E
Q
Site 21
Y205
Q
E
L
V
E
L
I
Y
Q
Q
A
T
S
I
P
Site 22
T209
E
L
I
Y
Q
Q
A
T
S
I
P
N
F
S
Y
Site 23
S226
A
R
L
C
N
Y
L
S
H
H
L
T
I
S
P
Site 24
T230
N
Y
L
S
H
H
L
T
I
S
P
Q
S
G
N
Site 25
S232
L
S
H
H
L
T
I
S
P
Q
S
G
N
F
R
Site 26
S235
H
L
T
I
S
P
Q
S
G
N
F
R
Q
L
L
Site 27
T248
L
L
L
Q
R
C
R
T
E
Y
E
V
K
D
Q
Site 28
Y250
L
Q
R
C
R
T
E
Y
E
V
K
D
Q
A
A
Site 29
T263
A
A
K
G
D
E
V
T
R
K
R
F
H
A
F
Site 30
T286
L
N
L
E
I
K
G
T
N
G
Q
V
T
R
A
Site 31
S328
K
L
L
K
L
T
G
S
V
L
E
D
A
W
K
Site 32
S374
L
K
L
V
E
L
R
S
S
N
W
G
R
V
H
Site 33
S375
K
L
V
E
L
R
S
S
N
W
G
R
V
H
A
Site 34
S384
W
G
R
V
H
A
T
S
T
Y
R
E
A
T
P
Site 35
Y386
R
V
H
A
T
S
T
Y
R
E
A
T
P
E
N
Site 36
T390
T
S
T
Y
R
E
A
T
P
E
N
D
P
N
Y
Site 37
Y397
T
P
E
N
D
P
N
Y
F
M
N
E
P
T
F
Site 38
Y405
F
M
N
E
P
T
F
Y
T
S
D
G
V
P
F
Site 39
Y419
F
T
A
A
D
P
D
Y
Q
E
K
Y
Q
E
L
Site 40
Y423
D
P
D
Y
Q
E
K
Y
Q
E
L
L
E
R
E
Site 41
Y436
R
E
D
F
F
P
D
Y
E
E
N
G
T
D
L
Site 42
T441
P
D
Y
E
E
N
G
T
D
L
S
G
A
G
D
Site 43
S444
E
E
N
G
T
D
L
S
G
A
G
D
P
Y
L
Site 44
Y450
L
S
G
A
G
D
P
Y
L
D
D
I
D
D
E
Site 45
S473
Y
E
K
F
C
L
E
S
E
R
K
R
K
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation