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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NXF2
Full Name:
Nuclear RNA export factor 2
Alias:
BA353J17.1; Nuclear RNA export factor 2B; TAP like 2; TAPL2; TAPL-2
Type:
Intracellular, Nuclear RNA export factor complex, Nucleolus, Cytoskeleton protein
Mass (Da):
71627
Number AA:
626
UniProt ID:
Q9GZY0
International Prot ID:
IPI00004931
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0042272
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0006406
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
S
T
L
K
K
C
G
T
Y
R
T
E
V
A
E
Site 2
S23
A
E
C
H
D
H
G
S
T
F
Q
G
R
K
K
Site 3
T24
E
C
H
D
H
G
S
T
F
Q
G
R
K
K
G
Site 4
S33
Q
G
R
K
K
G
G
S
S
F
R
D
N
F
D
Site 5
S34
G
R
K
K
G
G
S
S
F
R
D
N
F
D
K
Site 6
Y46
F
D
K
R
S
C
H
Y
E
H
G
G
Y
E
R
Site 7
Y51
C
H
Y
E
H
G
G
Y
E
R
P
P
S
H
C
Site 8
S56
G
G
Y
E
R
P
P
S
H
C
Q
E
N
D
G
Site 9
T79
K
D
Q
Q
L
R
H
T
P
Y
S
I
R
C
E
Site 10
Y81
Q
Q
L
R
H
T
P
Y
S
I
R
C
E
R
R
Site 11
S82
Q
L
R
H
T
P
Y
S
I
R
C
E
R
R
M
Site 12
S93
E
R
R
M
K
W
H
S
E
D
E
I
R
I
T
Site 13
T100
S
E
D
E
I
R
I
T
T
W
R
N
R
K
P
Site 14
T101
E
D
E
I
R
I
T
T
W
R
N
R
K
P
P
Site 15
S113
K
P
P
E
R
K
M
S
Q
N
T
Q
D
G
Y
Site 16
Y120
S
Q
N
T
Q
D
G
Y
T
R
N
W
F
K
V
Site 17
Y135
T
I
P
Y
G
I
K
Y
D
K
A
W
L
M
N
Site 18
S149
N
S
I
Q
S
H
C
S
D
R
F
T
P
V
D
Site 19
Y159
F
T
P
V
D
F
H
Y
V
R
N
R
A
C
F
Site 20
Y182
S
A
L
K
D
V
S
Y
K
I
Y
D
D
E
N
Site 21
Y185
K
D
V
S
Y
K
I
Y
D
D
E
N
Q
K
I
Site 22
Y203
V
N
H
S
T
A
P
Y
S
V
K
N
K
L
K
Site 23
S204
N
H
S
T
A
P
Y
S
V
K
N
K
L
K
P
Site 24
S274
R
N
F
P
E
L
L
S
L
N
L
C
N
N
K
Site 25
Y283
N
L
C
N
N
K
L
Y
Q
L
D
G
L
S
D
Site 26
S289
L
Y
Q
L
D
G
L
S
D
I
T
E
K
A
P
Site 27
T300
E
K
A
P
K
V
K
T
L
N
L
S
K
N
K
Site 28
S304
K
V
K
T
L
N
L
S
K
N
K
L
E
S
A
Site 29
S334
L
E
G
N
P
L
C
S
T
F
S
D
Q
S
A
Site 30
T335
E
G
N
P
L
C
S
T
F
S
D
Q
S
A
Y
Site 31
S337
N
P
L
C
S
T
F
S
D
Q
S
A
Y
V
S
Site 32
S340
C
S
T
F
S
D
Q
S
A
Y
V
S
A
I
R
Site 33
Y342
T
F
S
D
Q
S
A
Y
V
S
A
I
R
D
C
Site 34
S344
S
D
Q
S
A
Y
V
S
A
I
R
D
C
F
P
Site 35
S371
P
V
I
V
D
I
D
S
S
E
T
M
K
P
C
Site 36
S372
V
I
V
D
I
D
S
S
E
T
M
K
P
C
K
Site 37
S385
C
K
E
N
F
T
G
S
E
T
L
K
H
L
V
Site 38
Y399
V
L
Q
F
L
Q
Q
Y
Y
S
I
Y
D
S
G
Site 39
S401
Q
F
L
Q
Q
Y
Y
S
I
Y
D
S
G
D
R
Site 40
Y403
L
Q
Q
Y
Y
S
I
Y
D
S
G
D
R
Q
G
Site 41
S405
Q
Y
Y
S
I
Y
D
S
G
D
R
Q
G
L
L
Site 42
S432
I
P
F
D
P
K
D
S
A
P
S
S
L
C
K
Site 43
S436
P
K
D
S
A
P
S
S
L
C
K
Y
F
E
D
Site 44
Y440
A
P
S
S
L
C
K
Y
F
E
D
S
R
N
M
Site 45
T449
E
D
S
R
N
M
K
T
L
K
D
P
Y
L
K
Site 46
Y454
M
K
T
L
K
D
P
Y
L
K
G
E
L
L
R
Site 47
T463
K
G
E
L
L
R
R
T
K
R
D
I
V
D
S
Site 48
S470
T
K
R
D
I
V
D
S
L
S
A
L
P
K
T
Site 49
S472
R
D
I
V
D
S
L
S
A
L
P
K
T
Q
H
Site 50
T477
S
L
S
A
L
P
K
T
Q
H
D
L
S
S
I
Site 51
S511
F
K
E
V
E
G
Q
S
Q
G
S
V
L
A
F
Site 52
S531
A
T
P
G
S
S
S
S
L
C
I
V
N
D
E
Site 53
S545
E
L
F
V
R
D
A
S
P
Q
E
T
Q
S
A
Site 54
T549
R
D
A
S
P
Q
E
T
Q
S
A
F
S
I
P
Site 55
S551
A
S
P
Q
E
T
Q
S
A
F
S
I
P
V
S
Site 56
S554
Q
E
T
Q
S
A
F
S
I
P
V
S
T
L
S
Site 57
S558
S
A
F
S
I
P
V
S
T
L
S
S
S
S
E
Site 58
T559
A
F
S
I
P
V
S
T
L
S
S
S
S
E
P
Site 59
S561
S
I
P
V
S
T
L
S
S
S
S
E
P
S
L
Site 60
S562
I
P
V
S
T
L
S
S
S
S
E
P
S
L
S
Site 61
S563
P
V
S
T
L
S
S
S
S
E
P
S
L
S
Q
Site 62
S564
V
S
T
L
S
S
S
S
E
P
S
L
S
Q
E
Site 63
S567
L
S
S
S
S
E
P
S
L
S
Q
E
Q
Q
E
Site 64
S569
S
S
S
E
P
S
L
S
Q
E
Q
Q
E
M
V
Site 65
Y601
L
Q
D
N
E
W
N
Y
T
R
A
G
Q
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation