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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM14
Full Name:
PR domain zinc finger protein 14
Alias:
PR domain-containing protein 14
Type:
Mass (Da):
64062
Number AA:
571
UniProt ID:
Q9GZV8
International Prot ID:
IPI00001567
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
L
P
R
P
S
E
A
V
P
Q
D
K
Site 2
Y17
V
P
Q
D
K
V
C
Y
P
P
E
S
S
P
Q
Site 3
S21
K
V
C
Y
P
P
E
S
S
P
Q
N
L
A
A
Site 4
S22
V
C
Y
P
P
E
S
S
P
Q
N
L
A
A
Y
Site 5
Y29
S
P
Q
N
L
A
A
Y
Y
T
P
F
P
S
Y
Site 6
Y30
P
Q
N
L
A
A
Y
Y
T
P
F
P
S
Y
G
Site 7
T31
Q
N
L
A
A
Y
Y
T
P
F
P
S
Y
G
H
Site 8
Y36
Y
Y
T
P
F
P
S
Y
G
H
Y
R
N
S
L
Site 9
Y39
P
F
P
S
Y
G
H
Y
R
N
S
L
A
T
V
Site 10
S42
S
Y
G
H
Y
R
N
S
L
A
T
V
E
E
D
Site 11
T45
H
Y
R
N
S
L
A
T
V
E
E
D
F
Q
P
Site 12
S61
R
Q
L
E
A
A
A
S
A
A
P
A
M
P
P
Site 13
S79
R
M
A
P
P
L
L
S
P
G
L
G
L
Q
R
Site 14
Y90
G
L
Q
R
E
P
L
Y
D
L
P
W
Y
S
K
Site 15
Y95
P
L
Y
D
L
P
W
Y
S
K
L
P
P
W
Y
Site 16
Y102
Y
S
K
L
P
P
W
Y
P
I
P
H
V
P
R
Site 17
S116
R
E
V
P
P
F
L
S
S
S
H
E
Y
A
G
Site 18
S118
V
P
P
F
L
S
S
S
H
E
Y
A
G
A
S
Site 19
Y121
F
L
S
S
S
H
E
Y
A
G
A
S
S
E
D
Site 20
S125
S
H
E
Y
A
G
A
S
S
E
D
L
G
H
Q
Site 21
S140
I
I
G
G
D
N
E
S
G
P
C
C
G
P
D
Site 22
T148
G
P
C
C
G
P
D
T
L
I
P
P
P
P
A
Site 23
S158
P
P
P
P
A
D
A
S
L
L
P
E
G
L
R
Site 24
T166
L
L
P
E
G
L
R
T
S
Q
L
L
P
C
S
Site 25
S167
L
P
E
G
L
R
T
S
Q
L
L
P
C
S
P
Site 26
S173
T
S
Q
L
L
P
C
S
P
S
K
Q
S
E
D
Site 27
S175
Q
L
L
P
C
S
P
S
K
Q
S
E
D
G
P
Site 28
S185
S
E
D
G
P
K
P
S
N
Q
E
G
K
S
P
Site 29
S191
P
S
N
Q
E
G
K
S
P
A
R
F
Q
F
T
Site 30
S218
P
S
L
E
H
P
A
S
L
H
H
A
I
S
G
Site 31
S232
G
L
L
V
P
P
D
S
S
G
S
D
S
L
P
Site 32
S233
L
L
V
P
P
D
S
S
G
S
D
S
L
P
Q
Site 33
S235
V
P
P
D
S
S
G
S
D
S
L
P
Q
T
L
Site 34
S237
P
D
S
S
G
S
D
S
L
P
Q
T
L
D
K
Site 35
T241
G
S
D
S
L
P
Q
T
L
D
K
D
S
L
Q
Site 36
S246
P
Q
T
L
D
K
D
S
L
Q
L
P
E
G
L
Site 37
S291
Q
G
K
V
V
N
A
S
E
V
K
T
Y
G
D
Site 38
T295
V
N
A
S
E
V
K
T
Y
G
D
N
S
V
M
Site 39
Y296
N
A
S
E
V
K
T
Y
G
D
N
S
V
M
W
Site 40
T383
I
P
V
S
L
Q
V
T
E
P
G
K
Q
P
S
Site 41
S390
T
E
P
G
K
Q
P
S
G
P
S
E
E
S
A
Site 42
S393
G
K
Q
P
S
G
P
S
E
E
S
A
E
G
Y
Site 43
S396
P
S
G
P
S
E
E
S
A
E
G
Y
R
C
E
Site 44
Y400
S
E
E
S
A
E
G
Y
R
C
E
R
C
G
K
Site 45
Y411
R
C
G
K
V
F
T
Y
K
Y
Y
R
D
K
H
Site 46
Y413
G
K
V
F
T
Y
K
Y
Y
R
D
K
H
L
K
Site 47
Y414
K
V
F
T
Y
K
Y
Y
R
D
K
H
L
K
Y
Site 48
Y421
Y
R
D
K
H
L
K
Y
T
P
C
V
D
K
G
Site 49
T422
R
D
K
H
L
K
Y
T
P
C
V
D
K
G
D
Site 50
S435
G
D
R
K
F
P
C
S
L
C
K
R
S
F
E
Site 51
S440
P
C
S
L
C
K
R
S
F
E
K
R
D
R
L
Site 52
S471
S
T
C
G
K
C
F
S
Q
S
S
S
L
N
K
Site 53
S474
G
K
C
F
S
Q
S
S
S
L
N
K
H
M
R
Site 54
S475
K
C
F
S
Q
S
S
S
L
N
K
H
M
R
V
Site 55
Y489
V
H
S
G
D
R
P
Y
Q
C
V
Y
C
T
K
Site 56
Y493
D
R
P
Y
Q
C
V
Y
C
T
K
R
F
T
A
Site 57
T499
V
Y
C
T
K
R
F
T
A
S
S
I
L
R
T
Site 58
S502
T
K
R
F
T
A
S
S
I
L
R
T
H
I
R
Site 59
T506
T
A
S
S
I
L
R
T
H
I
R
Q
H
S
G
Site 60
S512
R
T
H
I
R
Q
H
S
G
E
K
P
F
K
C
Site 61
Y521
E
K
P
F
K
C
K
Y
C
G
K
S
F
A
S
Site 62
S534
A
S
H
A
A
H
D
S
H
V
R
R
S
H
K
Site 63
S539
H
D
S
H
V
R
R
S
H
K
E
D
D
G
C
Site 64
S556
S
I
C
G
K
I
F
S
D
Q
E
T
F
Y
S
Site 65
Y562
F
S
D
Q
E
T
F
Y
S
H
M
K
F
H
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation