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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PDGFD
Full Name:
Platelet-derived growth factor D
Alias:
IEGF; Iris-expressed growth factor; MSTP036; Platelet derived growth factor D; SCDGF-B; Spinal cord derived growth factor B; Spinal cord-derived growth factor-B
Type:
Secreted protein
Mass (Da):
42848
Number AA:
370
UniProt ID:
Q9GZP0
International Prot ID:
IPI00011865
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
GO:0051781
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
N
F
C
S
C
R
D
T
S
A
T
P
Q
S
A
Site 2
S22
F
C
S
C
R
D
T
S
A
T
P
Q
S
A
S
Site 3
T24
S
C
R
D
T
S
A
T
P
Q
S
A
S
I
K
Site 4
S27
D
T
S
A
T
P
Q
S
A
S
I
K
A
L
R
Site 5
S43
A
N
L
R
R
D
E
S
N
H
L
T
D
L
Y
Site 6
T47
R
D
E
S
N
H
L
T
D
L
Y
R
R
D
E
Site 7
Y50
S
N
H
L
T
D
L
Y
R
R
D
E
T
I
Q
Site 8
T55
D
L
Y
R
R
D
E
T
I
Q
V
K
G
N
G
Site 9
Y63
I
Q
V
K
G
N
G
Y
V
Q
S
P
R
F
P
Site 10
S66
K
G
N
G
Y
V
Q
S
P
R
F
P
N
S
Y
Site 11
S72
Q
S
P
R
F
P
N
S
Y
P
R
N
L
L
L
Site 12
Y73
S
P
R
F
P
N
S
Y
P
R
N
L
L
L
T
Site 13
T80
Y
P
R
N
L
L
L
T
W
R
L
H
S
Q
E
Site 14
S85
L
L
T
W
R
L
H
S
Q
E
N
T
R
I
Q
Site 15
T89
R
L
H
S
Q
E
N
T
R
I
Q
L
V
F
D
Site 16
Y111
A
E
N
D
I
C
R
Y
D
F
V
E
V
E
D
Site 17
S120
F
V
E
V
E
D
I
S
E
T
S
T
I
I
R
Site 18
T124
E
D
I
S
E
T
S
T
I
I
R
G
R
W
C
Site 19
S142
E
V
P
P
R
I
K
S
R
T
N
Q
I
K
I
Site 20
T144
P
P
R
I
K
S
R
T
N
Q
I
K
I
T
F
Site 21
T150
R
T
N
Q
I
K
I
T
F
K
S
D
D
Y
F
Site 22
Y156
I
T
F
K
S
D
D
Y
F
V
A
K
P
G
F
Site 23
Y166
A
K
P
G
F
K
I
Y
Y
S
L
L
E
D
F
Site 24
S168
P
G
F
K
I
Y
Y
S
L
L
E
D
F
Q
P
Site 25
S185
A
S
E
T
N
W
E
S
V
T
S
S
I
S
G
Site 26
T187
E
T
N
W
E
S
V
T
S
S
I
S
G
V
S
Site 27
S188
T
N
W
E
S
V
T
S
S
I
S
G
V
S
Y
Site 28
S189
N
W
E
S
V
T
S
S
I
S
G
V
S
Y
N
Site 29
S191
E
S
V
T
S
S
I
S
G
V
S
Y
N
S
P
Site 30
S194
T
S
S
I
S
G
V
S
Y
N
S
P
S
V
T
Site 31
Y195
S
S
I
S
G
V
S
Y
N
S
P
S
V
T
D
Site 32
S197
I
S
G
V
S
Y
N
S
P
S
V
T
D
P
T
Site 33
S199
G
V
S
Y
N
S
P
S
V
T
D
P
T
L
I
Site 34
T201
S
Y
N
S
P
S
V
T
D
P
T
L
I
A
D
Site 35
T219
K
K
I
A
E
F
D
T
V
E
D
L
L
K
Y
Site 36
Y226
T
V
E
D
L
L
K
Y
F
N
P
E
S
W
Q
Site 37
S231
L
K
Y
F
N
P
E
S
W
Q
E
D
L
E
N
Site 38
Y240
Q
E
D
L
E
N
M
Y
L
D
T
P
R
Y
R
Site 39
T243
L
E
N
M
Y
L
D
T
P
R
Y
R
G
R
S
Site 40
Y246
M
Y
L
D
T
P
R
Y
R
G
R
S
Y
H
D
Site 41
S250
T
P
R
Y
R
G
R
S
Y
H
D
R
K
S
K
Site 42
Y251
P
R
Y
R
G
R
S
Y
H
D
R
K
S
K
V
Site 43
S256
R
S
Y
H
D
R
K
S
K
V
D
L
D
R
L
Site 44
S271
N
D
D
A
K
R
Y
S
C
T
P
R
N
Y
S
Site 45
T273
D
A
K
R
Y
S
C
T
P
R
N
Y
S
V
N
Site 46
Y277
Y
S
C
T
P
R
N
Y
S
V
N
I
R
E
E
Site 47
S278
S
C
T
P
R
N
Y
S
V
N
I
R
E
E
L
Site 48
Y327
S
G
K
T
V
K
K
Y
H
E
V
L
Q
F
E
Site 49
T346
K
R
R
G
R
A
K
T
M
A
L
V
D
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation