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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR12
Full Name:
Ribosome biogenesis protein WDR12
Alias:
WD repeat 12; YTM1
Type:
Mass (Da):
47708
Number AA:
423
UniProt ID:
Q9GZL7
International Prot ID:
IPI00304232
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070545
GO:0005654
GO:0030687
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0000466
GO:0000463
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
A
Q
L
Q
T
R
F
Y
T
D
N
K
K
Y
A
Site 2
T10
Q
L
Q
T
R
F
Y
T
D
N
K
K
Y
A
V
Site 3
Y15
F
Y
T
D
N
K
K
Y
A
V
D
D
V
P
F
Site 4
S23
A
V
D
D
V
P
F
S
I
P
A
A
S
E
I
Site 5
S77
M
E
M
E
N
I
S
S
E
E
V
V
E
I
E
Site 6
Y85
E
E
V
V
E
I
E
Y
V
E
K
Y
T
A
P
Site 7
Y89
E
I
E
Y
V
E
K
Y
T
A
P
Q
P
E
Q
Site 8
T116
G
A
E
E
W
I
L
T
G
S
Y
D
K
T
S
Site 9
S118
E
E
W
I
L
T
G
S
Y
D
K
T
S
R
I
Site 10
Y119
E
W
I
L
T
G
S
Y
D
K
T
S
R
I
W
Site 11
T122
L
T
G
S
Y
D
K
T
S
R
I
W
S
L
E
Site 12
S123
T
G
S
Y
D
K
T
S
R
I
W
S
L
E
G
Site 13
S127
D
K
T
S
R
I
W
S
L
E
G
K
S
I
M
Site 14
S194
G
H
A
G
S
V
D
S
I
A
V
D
G
S
G
Site 15
S200
D
S
I
A
V
D
G
S
G
T
K
F
C
S
G
Site 16
S206
G
S
G
T
K
F
C
S
G
S
W
D
K
M
L
Site 17
S208
G
T
K
F
C
S
G
S
W
D
K
M
L
K
I
Site 18
S217
D
K
M
L
K
I
W
S
T
V
P
T
D
E
E
Site 19
T218
K
M
L
K
I
W
S
T
V
P
T
D
E
E
D
Site 20
T221
K
I
W
S
T
V
P
T
D
E
E
D
E
M
E
Site 21
S230
E
E
D
E
M
E
E
S
T
N
R
P
R
K
K
Site 22
T240
R
P
R
K
K
Q
K
T
E
Q
L
G
L
T
R
Site 23
T246
K
T
E
Q
L
G
L
T
R
T
P
I
V
T
L
Site 24
S254
R
T
P
I
V
T
L
S
G
H
M
E
A
V
S
Site 25
S261
S
G
H
M
E
A
V
S
S
V
L
W
S
D
A
Site 26
S262
G
H
M
E
A
V
S
S
V
L
W
S
D
A
E
Site 27
S273
S
D
A
E
E
I
C
S
A
S
W
D
H
T
I
Site 28
S289
V
W
D
V
E
S
G
S
L
K
S
T
L
T
G
Site 29
T293
E
S
G
S
L
K
S
T
L
T
G
N
K
V
F
Site 30
T295
G
S
L
K
S
T
L
T
G
N
K
V
F
N
C
Site 31
S314
P
L
C
K
R
L
A
S
G
S
T
D
R
H
I
Site 32
S316
C
K
R
L
A
S
G
S
T
D
R
H
I
R
L
Site 33
T317
K
R
L
A
S
G
S
T
D
R
H
I
R
L
W
Site 34
T328
I
R
L
W
D
P
R
T
K
D
G
S
L
V
S
Site 35
S332
D
P
R
T
K
D
G
S
L
V
S
L
S
L
T
Site 36
S335
T
K
D
G
S
L
V
S
L
S
L
T
S
H
T
Site 37
S337
D
G
S
L
V
S
L
S
L
T
S
H
T
G
W
Site 38
S351
W
V
T
S
V
K
W
S
P
T
H
E
Q
Q
L
Site 39
S362
E
Q
Q
L
I
S
G
S
L
D
N
I
V
K
L
Site 40
S374
V
K
L
W
D
T
R
S
C
K
A
P
L
Y
D
Site 41
Y380
R
S
C
K
A
P
L
Y
D
L
A
A
H
E
D
Site 42
S391
A
H
E
D
K
V
L
S
V
D
W
T
D
T
G
Site 43
Y410
G
G
A
D
N
K
L
Y
S
Y
R
Y
S
P
T
Site 44
S411
G
A
D
N
K
L
Y
S
Y
R
Y
S
P
T
T
Site 45
S415
K
L
Y
S
Y
R
Y
S
P
T
T
S
H
V
G
Site 46
T418
S
Y
R
Y
S
P
T
T
S
H
V
G
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation