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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR12
Full Name:
Myotubularin-related protein 12
Alias:
Phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit
Type:
Mass (Da):
86148
Number AA:
747
UniProt ID:
Q9C0I1
International Prot ID:
IPI00448020
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004437
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
GO:0006629
GO:0006793
GO:0006796
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
V
V
G
G
G
G
G
T
K
A
P
K
P
S
F
Site 2
S19
G
T
K
A
P
K
P
S
F
V
S
Y
V
R
P
Site 3
Y23
P
K
P
S
F
V
S
Y
V
R
P
E
E
I
H
Site 4
T31
V
R
P
E
E
I
H
T
N
E
K
E
V
T
E
Site 5
T37
H
T
N
E
K
E
V
T
E
K
E
V
T
L
H
Site 6
T42
E
V
T
E
K
E
V
T
L
H
L
L
P
G
E
Site 7
Y61
E
A
S
T
V
L
K
Y
V
Q
E
D
S
C
Q
Site 8
Y72
D
S
C
Q
H
G
V
Y
G
R
L
V
C
T
D
Site 9
S90
A
F
L
G
D
D
E
S
A
L
D
N
D
E
T
Site 10
T97
S
A
L
D
N
D
E
T
Q
F
K
N
K
V
I
Site 11
Y118
L
H
C
V
D
Q
I
Y
G
V
F
D
E
K
K
Site 12
T127
V
F
D
E
K
K
K
T
L
F
G
Q
L
K
K
Site 13
Y135
L
F
G
Q
L
K
K
Y
P
E
K
L
I
I
H
Site 14
T156
F
Q
F
C
L
R
Y
T
K
E
E
E
V
K
R
Site 15
S166
E
E
V
K
R
I
V
S
G
I
I
H
H
T
Q
Site 16
Y186
K
R
L
F
L
F
S
Y
A
T
A
A
Q
N
N
Site 17
Y224
R
T
K
G
N
M
K
Y
K
A
V
S
V
N
E
Site 18
S295
G
I
L
Q
I
Q
K
S
F
L
D
G
I
Y
K
Site 19
Y301
K
S
F
L
D
G
I
Y
K
T
I
H
R
P
P
Site 20
T303
F
L
D
G
I
Y
K
T
I
H
R
P
P
Y
E
Site 21
Y309
K
T
I
H
R
P
P
Y
E
I
V
K
T
E
D
Site 22
T314
P
P
Y
E
I
V
K
T
E
D
L
S
S
N
F
Site 23
S318
I
V
K
T
E
D
L
S
S
N
F
L
S
L
Q
Site 24
S319
V
K
T
E
D
L
S
S
N
F
L
S
L
Q
E
Site 25
S323
D
L
S
S
N
F
L
S
L
Q
E
I
Q
T
A
Site 26
S355
D
T
D
I
K
W
F
S
L
L
E
S
S
S
W
Site 27
S361
F
S
L
L
E
S
S
S
W
L
D
I
I
R
R
Site 28
S421
R
T
R
I
G
F
Q
S
L
I
Q
K
E
W
V
Site 29
T478
E
F
T
E
T
Y
L
T
V
L
S
D
S
L
Y
Site 30
S496
F
S
T
F
F
F
N
S
P
H
Q
K
D
T
N
Site 31
T502
N
S
P
H
Q
K
D
T
N
M
G
R
E
G
Q
Site 32
T511
M
G
R
E
G
Q
D
T
Q
S
K
P
L
N
L
Site 33
T520
S
K
P
L
N
L
L
T
V
W
D
W
S
V
Q
Site 34
Y541
T
L
L
K
N
P
L
Y
V
E
K
P
K
L
D
Site 35
S564
F
K
H
Q
R
Q
L
S
L
P
L
T
Q
S
K
Site 36
T568
R
Q
L
S
L
P
L
T
Q
S
K
S
S
P
K
Site 37
S570
L
S
L
P
L
T
Q
S
K
S
S
P
K
R
G
Site 38
S572
L
P
L
T
Q
S
K
S
S
P
K
R
G
F
F
Site 39
S573
P
L
T
Q
S
K
S
S
P
K
R
G
F
F
R
Site 40
T583
R
G
F
F
R
E
E
T
D
H
L
I
K
N
L
Site 41
S596
N
L
L
G
K
R
I
S
K
L
I
N
S
S
D
Site 42
S602
I
S
K
L
I
N
S
S
D
E
L
Q
D
N
F
Site 43
Y613
Q
D
N
F
R
E
F
Y
D
S
W
H
S
K
S
Site 44
Y623
W
H
S
K
S
T
D
Y
H
G
L
L
L
P
H
Site 45
Y643
I
K
V
W
A
Q
R
Y
L
R
W
I
P
E
A
Site 46
S673
E
M
M
E
E
V
Q
S
L
Q
E
K
I
D
E
Site 47
S684
K
I
D
E
R
H
H
S
Q
Q
A
P
Q
A
E
Site 48
S699
A
P
C
L
L
R
N
S
A
R
L
S
S
L
F
Site 49
S715
F
A
L
L
Q
R
H
S
S
K
P
V
L
P
T
Site 50
S716
A
L
L
Q
R
H
S
S
K
P
V
L
P
T
S
Site 51
S723
S
K
P
V
L
P
T
S
G
W
K
A
L
G
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation