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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF436
Full Name:
Zinc finger protein 436
Alias:
Type:
Mass (Da):
54277
Number AA:
470
UniProt ID:
Q9C0F3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
A
G
S
Q
A
P
V
T
F
E
D
M
A
M
Y
Site 2
Y22
T
F
E
D
M
A
M
Y
L
T
R
E
E
W
R
Site 3
Y39
D
A
A
Q
R
D
L
Y
R
D
V
M
Q
E
N
Site 4
Y47
R
D
V
M
Q
E
N
Y
G
N
V
V
S
L
D
Site 5
S52
E
N
Y
G
N
V
V
S
L
D
F
E
I
R
S
Site 6
S79
D
V
Q
F
G
T
T
S
E
R
P
A
E
N
A
Site 7
S92
N
A
E
E
N
P
E
S
E
E
G
F
E
S
G
Site 8
S98
E
S
E
E
G
F
E
S
G
D
R
S
E
R
Q
Site 9
S102
G
F
E
S
G
D
R
S
E
R
Q
W
G
D
L
Site 10
T110
E
R
Q
W
G
D
L
T
A
E
E
W
V
S
Y
Site 11
S116
L
T
A
E
E
W
V
S
Y
P
L
Q
P
V
T
Site 12
Y117
T
A
E
E
W
V
S
Y
P
L
Q
P
V
T
D
Site 13
S148
S
H
C
G
K
A
F
S
Q
I
S
D
L
N
R
Site 14
S151
G
K
A
F
S
Q
I
S
D
L
N
R
H
Q
K
Site 15
Y166
T
H
T
G
D
R
P
Y
K
C
Y
E
C
G
K
Site 16
Y169
G
D
R
P
Y
K
C
Y
E
C
G
K
G
F
S
Site 17
S176
Y
E
C
G
K
G
F
S
R
S
S
H
L
I
Q
Site 18
S178
C
G
K
G
F
S
R
S
S
H
L
I
Q
H
Q
Site 19
S179
G
K
G
F
S
R
S
S
H
L
I
Q
H
Q
R
Site 20
T189
I
Q
H
Q
R
T
H
T
G
E
R
P
Y
D
C
Site 21
Y194
T
H
T
G
E
R
P
Y
D
C
N
E
C
G
K
Site 22
S202
D
C
N
E
C
G
K
S
F
G
R
S
S
H
L
Site 23
S206
C
G
K
S
F
G
R
S
S
H
L
I
Q
H
Q
Site 24
S207
G
K
S
F
G
R
S
S
H
L
I
Q
H
Q
T
Site 25
S235
G
K
S
F
C
R
L
S
H
L
I
Q
H
Q
R
Site 26
S245
I
Q
H
Q
R
T
H
S
G
E
K
P
Y
E
C
Site 27
Y250
T
H
S
G
E
K
P
Y
E
C
E
E
C
G
K
Site 28
S258
E
C
E
E
C
G
K
S
F
S
R
S
S
H
L
Site 29
S260
E
E
C
G
K
S
F
S
R
S
S
H
L
A
Q
Site 30
S262
C
G
K
S
F
S
R
S
S
H
L
A
Q
H
Q
Site 31
S263
G
K
S
F
S
R
S
S
H
L
A
Q
H
Q
R
Site 32
T271
H
L
A
Q
H
Q
R
T
H
T
G
E
K
P
Y
Site 33
T273
A
Q
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 34
Y278
T
H
T
G
E
K
P
Y
E
C
N
E
C
G
R
Site 35
S288
N
E
C
G
R
G
F
S
E
R
S
D
L
I
K
Site 36
S291
G
R
G
F
S
E
R
S
D
L
I
K
H
Y
R
Site 37
Y297
R
S
D
L
I
K
H
Y
R
V
H
T
G
E
R
Site 38
T301
I
K
H
Y
R
V
H
T
G
E
R
P
Y
K
C
Site 39
Y306
V
H
T
G
E
R
P
Y
K
C
D
E
C
G
K
Site 40
S316
D
E
C
G
K
N
F
S
Q
N
S
D
L
V
R
Site 41
S319
G
K
N
F
S
Q
N
S
D
L
V
R
H
R
R
Site 42
T329
V
R
H
R
R
A
H
T
G
E
K
P
Y
H
C
Site 43
Y334
A
H
T
G
E
K
P
Y
H
C
N
E
C
G
E
Site 44
S347
G
E
N
F
S
R
I
S
H
L
V
Q
H
Q
R
Site 45
T355
H
L
V
Q
H
Q
R
T
H
T
G
E
K
P
Y
Site 46
T357
V
Q
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 47
Y362
T
H
T
G
E
K
P
Y
E
C
N
A
C
G
K
Site 48
S370
E
C
N
A
C
G
K
S
F
S
R
S
S
H
L
Site 49
S372
N
A
C
G
K
S
F
S
R
S
S
H
L
I
T
Site 50
S374
C
G
K
S
F
S
R
S
S
H
L
I
T
H
Q
Site 51
S375
G
K
S
F
S
R
S
S
H
L
I
T
H
Q
K
Site 52
T379
S
R
S
S
H
L
I
T
H
Q
K
I
H
T
G
Site 53
T385
I
T
H
Q
K
I
H
T
G
E
K
P
Y
E
C
Site 54
Y390
I
H
T
G
E
K
P
Y
E
C
N
E
C
W
R
Site 55
T411
D
L
I
K
H
Q
R
T
H
T
G
E
K
P
Y
Site 56
T413
I
K
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 57
Y418
T
H
T
G
E
K
P
Y
E
C
V
Q
C
G
K
Site 58
S430
C
G
K
G
F
T
Q
S
S
N
L
I
T
H
Q
Site 59
S431
G
K
G
F
T
Q
S
S
N
L
I
T
H
Q
R
Site 60
T435
T
Q
S
S
N
L
I
T
H
Q
R
V
H
T
G
Site 61
T441
I
T
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 62
Y446
V
H
T
G
E
K
P
Y
E
C
T
E
C
E
K
Site 63
T449
G
E
K
P
Y
E
C
T
E
C
E
K
S
F
S
Site 64
S454
E
C
T
E
C
E
K
S
F
S
R
S
S
A
L
Site 65
S456
T
E
C
E
K
S
F
S
R
S
S
A
L
I
K
Site 66
S458
C
E
K
S
F
S
R
S
S
A
L
I
K
H
K
Site 67
S459
E
K
S
F
S
R
S
S
A
L
I
K
H
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation