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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SETD5
Full Name:
SET domain-containing protein 5
Alias:
KIAA1757
Type:
Unknown function
Mass (Da):
157515
Number AA:
1442
UniProt ID:
Q9C0A6
International Prot ID:
IPI00741882
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
A
I
P
L
G
V
T
T
S
D
T
S
Y
S
D
Site 2
S12
I
P
L
G
V
T
T
S
D
T
S
Y
S
D
M
Site 3
S15
G
V
T
T
S
D
T
S
Y
S
D
M
A
A
G
Site 4
Y16
V
T
T
S
D
T
S
Y
S
D
M
A
A
G
S
Site 5
S17
T
T
S
D
T
S
Y
S
D
M
A
A
G
S
D
Site 6
S23
Y
S
D
M
A
A
G
S
D
P
E
S
V
E
A
Site 7
S27
A
A
G
S
D
P
E
S
V
E
A
S
P
A
V
Site 8
S31
D
P
E
S
V
E
A
S
P
A
V
N
E
K
S
Site 9
S38
S
P
A
V
N
E
K
S
V
Y
S
T
H
N
Y
Site 10
Y40
A
V
N
E
K
S
V
Y
S
T
H
N
Y
G
T
Site 11
T42
N
E
K
S
V
Y
S
T
H
N
Y
G
T
T
Q
Site 12
Y45
S
V
Y
S
T
H
N
Y
G
T
T
Q
R
H
G
Site 13
T48
S
T
H
N
Y
G
T
T
Q
R
H
G
C
R
G
Site 14
Y58
H
G
C
R
G
L
P
Y
A
T
I
I
P
R
S
Site 15
S65
Y
A
T
I
I
P
R
S
D
L
N
G
L
P
S
Site 16
S72
S
D
L
N
G
L
P
S
P
V
E
E
R
C
G
Site 17
S81
V
E
E
R
C
G
D
S
P
N
S
E
G
E
T
Site 18
S84
R
C
G
D
S
P
N
S
E
G
E
T
V
P
T
Site 19
T88
S
P
N
S
E
G
E
T
V
P
T
W
C
P
C
Site 20
T91
S
E
G
E
T
V
P
T
W
C
P
C
G
L
S
Site 21
S113
C
D
K
C
R
G
M
S
R
G
K
V
I
R
L
Site 22
S129
R
R
K
Q
D
N
I
S
G
G
D
S
S
A
T
Site 23
S133
D
N
I
S
G
G
D
S
S
A
T
E
S
W
D
Site 24
S134
N
I
S
G
G
D
S
S
A
T
E
S
W
D
E
Site 25
T136
S
G
G
D
S
S
A
T
E
S
W
D
E
E
L
Site 26
S138
G
D
S
S
A
T
E
S
W
D
E
E
L
S
P
Site 27
S144
E
S
W
D
E
E
L
S
P
S
T
V
L
Y
T
Site 28
S146
W
D
E
E
L
S
P
S
T
V
L
Y
T
A
T
Site 29
Y150
L
S
P
S
T
V
L
Y
T
A
T
Q
H
T
P
Site 30
T156
L
Y
T
A
T
Q
H
T
P
T
S
I
T
L
T
Site 31
S159
A
T
Q
H
T
P
T
S
I
T
L
T
V
R
R
Site 32
T163
T
P
T
S
I
T
L
T
V
R
R
T
K
P
K
Site 33
T167
I
T
L
T
V
R
R
T
K
P
K
K
R
K
K
Site 34
S175
K
P
K
K
R
K
K
S
P
E
K
G
R
A
A
Site 35
T185
K
G
R
A
A
P
K
T
K
K
I
K
N
S
P
Site 36
S191
K
T
K
K
I
K
N
S
P
S
E
A
Q
N
L
Site 37
S193
K
K
I
K
N
S
P
S
E
A
Q
N
L
D
E
Site 38
T214
E
N
R
I
R
L
W
T
D
Q
Y
E
E
A
F
Site 39
Y217
I
R
L
W
T
D
Q
Y
E
E
A
F
T
N
Q
Site 40
T222
D
Q
Y
E
E
A
F
T
N
Q
Y
S
A
D
V
Site 41
T252
G
K
P
T
I
L
D
T
I
N
K
T
E
L
A
Site 42
T263
T
E
L
A
C
N
N
T
V
I
G
S
Q
M
Q
Site 43
T277
Q
L
Q
L
G
R
V
T
R
V
Q
K
H
R
K
Site 44
Y322
G
H
F
F
K
K
P
Y
P
F
V
L
F
Y
S
Site 45
S353
D
A
R
F
I
R
R
S
C
T
P
N
A
E
V
Site 46
T355
R
F
I
R
R
S
C
T
P
N
A
E
V
R
H
Site 47
Y391
E
V
T
I
A
F
D
Y
E
Y
S
N
C
N
Y
Site 48
Y393
T
I
A
F
D
Y
E
Y
S
N
C
N
Y
K
V
Site 49
T421
Q
K
R
N
P
N
A
T
E
L
P
L
L
P
P
Site 50
S466
E
E
N
N
D
Q
Q
S
Q
E
V
P
E
K
V
Site 51
T474
Q
E
V
P
E
K
V
T
V
S
S
D
H
E
E
Site 52
S506
D
Q
E
N
L
A
H
S
R
R
T
R
E
D
R
Site 53
T509
N
L
A
H
S
R
R
T
R
E
D
R
K
V
E
Site 54
S539
R
D
Q
P
L
E
Q
S
N
S
D
V
E
I
T
Site 55
S541
Q
P
L
E
Q
S
N
S
D
V
E
I
T
T
T
Site 56
T548
S
D
V
E
I
T
T
T
T
S
E
T
P
V
G
Site 57
S550
V
E
I
T
T
T
T
S
E
T
P
V
G
E
E
Site 58
T552
I
T
T
T
T
S
E
T
P
V
G
E
E
T
K
Site 59
T560
P
V
G
E
E
T
K
T
E
A
P
E
S
E
V
Site 60
S565
T
K
T
E
A
P
E
S
E
V
S
N
S
V
S
Site 61
S568
E
A
P
E
S
E
V
S
N
S
V
S
N
V
T
Site 62
S570
P
E
S
E
V
S
N
S
V
S
N
V
T
I
P
Site 63
S572
S
E
V
S
N
S
V
S
N
V
T
I
P
S
T
Site 64
T575
S
N
S
V
S
N
V
T
I
P
S
T
P
Q
S
Site 65
T579
S
N
V
T
I
P
S
T
P
Q
S
V
G
V
N
Site 66
S582
T
I
P
S
T
P
Q
S
V
G
V
N
T
R
R
Site 67
T587
P
Q
S
V
G
V
N
T
R
R
S
S
Q
A
G
Site 68
S590
V
G
V
N
T
R
R
S
S
Q
A
G
D
I
A
Site 69
S591
G
V
N
T
R
R
S
S
Q
A
G
D
I
A
A
Site 70
S611
K
P
P
P
A
K
P
S
R
P
R
P
K
S
R
Site 71
S617
P
S
R
P
R
P
K
S
R
I
S
R
Y
R
T
Site 72
S620
P
R
P
K
S
R
I
S
R
Y
R
T
S
S
A
Site 73
Y622
P
K
S
R
I
S
R
Y
R
T
S
S
A
Q
R
Site 74
T624
S
R
I
S
R
Y
R
T
S
S
A
Q
R
L
K
Site 75
S625
R
I
S
R
Y
R
T
S
S
A
Q
R
L
K
R
Site 76
S626
I
S
R
Y
R
T
S
S
A
Q
R
L
K
R
Q
Site 77
S644
N
A
Q
Q
A
E
L
S
Q
A
A
L
E
E
G
Site 78
S653
A
A
L
E
E
G
G
S
N
S
L
V
T
P
T
Site 79
S655
L
E
E
G
G
S
N
S
L
V
T
P
T
E
A
Site 80
T658
G
G
S
N
S
L
V
T
P
T
E
A
G
S
L
Site 81
T660
S
N
S
L
V
T
P
T
E
A
G
S
L
D
S
Site 82
S664
V
T
P
T
E
A
G
S
L
D
S
S
G
E
N
Site 83
S668
E
A
G
S
L
D
S
S
G
E
N
R
P
L
T
Site 84
T675
S
G
E
N
R
P
L
T
G
S
D
P
T
V
V
Site 85
S677
E
N
R
P
L
T
G
S
D
P
T
V
V
S
I
Site 86
S683
G
S
D
P
T
V
V
S
I
T
G
S
H
V
N
Site 87
S694
S
H
V
N
R
A
A
S
K
Y
P
K
T
K
K
Site 88
Y696
V
N
R
A
A
S
K
Y
P
K
T
K
K
Y
L
Site 89
T699
A
A
S
K
Y
P
K
T
K
K
Y
L
V
T
E
Site 90
Y702
K
Y
P
K
T
K
K
Y
L
V
T
E
W
L
N
Site 91
Y755
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Site 92
S760
K
H
Y
I
R
F
G
S
P
F
I
P
E
R
R
Site 93
T776
R
P
L
L
P
D
G
T
F
S
S
C
K
K
R
Site 94
S778
L
L
P
D
G
T
F
S
S
C
K
K
R
W
I
Site 95
S779
L
P
D
G
T
F
S
S
C
K
K
R
W
I
K
Site 96
T794
Q
A
L
E
E
G
M
T
Q
T
S
S
V
P
Q
Site 97
S798
E
G
M
T
Q
T
S
S
V
P
Q
E
T
R
T
Site 98
Y809
E
T
R
T
Q
H
L
Y
Q
S
N
E
N
S
S
Site 99
S811
R
T
Q
H
L
Y
Q
S
N
E
N
S
S
S
S
Site 100
S815
L
Y
Q
S
N
E
N
S
S
S
S
S
I
C
K
Site 101
S816
Y
Q
S
N
E
N
S
S
S
S
S
I
C
K
D
Site 102
S817
Q
S
N
E
N
S
S
S
S
S
I
C
K
D
N
Site 103
S819
N
E
N
S
S
S
S
S
I
C
K
D
N
A
D
Site 104
S829
K
D
N
A
D
L
L
S
P
L
K
K
W
K
S
Site 105
S836
S
P
L
K
K
W
K
S
R
Y
L
M
E
Q
N
Site 106
Y838
L
K
K
W
K
S
R
Y
L
M
E
Q
N
V
T
Site 107
T845
Y
L
M
E
Q
N
V
T
K
L
L
R
P
L
S
Site 108
S852
T
K
L
L
R
P
L
S
P
V
T
P
P
P
P
Site 109
T855
L
R
P
L
S
P
V
T
P
P
P
P
N
S
G
Site 110
S861
V
T
P
P
P
P
N
S
G
S
K
S
P
Q
L
Site 111
S863
P
P
P
P
N
S
G
S
K
S
P
Q
L
A
T
Site 112
S865
P
P
N
S
G
S
K
S
P
Q
L
A
T
P
G
Site 113
T870
S
K
S
P
Q
L
A
T
P
G
S
S
H
P
G
Site 114
S873
P
Q
L
A
T
P
G
S
S
H
P
G
E
E
E
Site 115
Y885
E
E
E
C
R
N
G
Y
S
L
M
F
S
P
V
Site 116
S886
E
E
C
R
N
G
Y
S
L
M
F
S
P
V
T
Site 117
S890
N
G
Y
S
L
M
F
S
P
V
T
S
L
T
T
Site 118
T896
F
S
P
V
T
S
L
T
T
A
S
R
C
N
T
Site 119
S899
V
T
S
L
T
T
A
S
R
C
N
T
P
L
Q
Site 120
T903
T
T
A
S
R
C
N
T
P
L
Q
F
E
L
C
Site 121
Y922
L
D
L
A
K
V
G
Y
L
D
S
N
T
N
S
Site 122
S925
A
K
V
G
Y
L
D
S
N
T
N
S
C
A
D
Site 123
T927
V
G
Y
L
D
S
N
T
N
S
C
A
D
R
P
Site 124
S929
Y
L
D
S
N
T
N
S
C
A
D
R
P
S
L
Site 125
S935
N
S
C
A
D
R
P
S
L
L
N
S
G
H
S
Site 126
S939
D
R
P
S
L
L
N
S
G
H
S
D
L
A
P
Site 127
S942
S
L
L
N
S
G
H
S
D
L
A
P
H
P
S
Site 128
S949
S
D
L
A
P
H
P
S
L
G
P
T
S
E
T
Site 129
T953
P
H
P
S
L
G
P
T
S
E
T
G
F
P
S
Site 130
S954
H
P
S
L
G
P
T
S
E
T
G
F
P
S
R
Site 131
T956
S
L
G
P
T
S
E
T
G
F
P
S
R
S
G
Site 132
S960
T
S
E
T
G
F
P
S
R
S
G
D
G
H
Q
Site 133
T968
R
S
G
D
G
H
Q
T
L
V
R
N
S
D
Q
Site 134
S973
H
Q
T
L
V
R
N
S
D
Q
A
F
R
T
E
Site 135
Y985
R
T
E
F
N
L
M
Y
A
Y
S
P
L
N
A
Site 136
Y987
E
F
N
L
M
Y
A
Y
S
P
L
N
A
M
P
Site 137
S988
F
N
L
M
Y
A
Y
S
P
L
N
A
M
P
R
Site 138
Y1000
M
P
R
A
D
G
L
Y
R
G
S
P
L
V
G
Site 139
S1003
A
D
G
L
Y
R
G
S
P
L
V
G
D
R
K
Site 140
Y1018
P
L
H
L
D
G
G
Y
C
S
P
A
E
G
F
Site 141
S1020
H
L
D
G
G
Y
C
S
P
A
E
G
F
S
S
Site 142
S1026
C
S
P
A
E
G
F
S
S
R
Y
E
H
G
L
Site 143
S1027
S
P
A
E
G
F
S
S
R
Y
E
H
G
L
M
Site 144
Y1029
A
E
G
F
S
S
R
Y
E
H
G
L
M
K
D
Site 145
S1038
H
G
L
M
K
D
L
S
R
G
S
L
S
P
G
Site 146
S1041
M
K
D
L
S
R
G
S
L
S
P
G
G
E
R
Site 147
S1043
D
L
S
R
G
S
L
S
P
G
G
E
R
A
C
Site 148
S1055
R
A
C
E
G
V
P
S
A
P
Q
N
P
P
Q
Site 149
Y1071
K
K
V
S
L
L
E
Y
R
K
R
K
Q
E
A
Site 150
S1089
S
A
G
G
G
G
D
S
A
Q
S
K
S
K
S
Site 151
S1092
G
G
G
D
S
A
Q
S
K
S
K
S
A
G
A
Site 152
S1094
G
D
S
A
Q
S
K
S
K
S
A
G
A
G
Q
Site 153
S1096
S
A
Q
S
K
S
K
S
A
G
A
G
Q
G
S
Site 154
S1103
S
A
G
A
G
Q
G
S
S
N
S
V
S
D
T
Site 155
S1104
A
G
A
G
Q
G
S
S
N
S
V
S
D
T
G
Site 156
S1106
A
G
Q
G
S
S
N
S
V
S
D
T
G
A
H
Site 157
S1108
Q
G
S
S
N
S
V
S
D
T
G
A
H
G
V
Site 158
T1110
S
S
N
S
V
S
D
T
G
A
H
G
V
Q
G
Site 159
S1118
G
A
H
G
V
Q
G
S
S
A
R
T
P
S
S
Site 160
S1119
A
H
G
V
Q
G
S
S
A
R
T
P
S
S
P
Site 161
T1122
V
Q
G
S
S
A
R
T
P
S
S
P
H
K
K
Site 162
S1124
G
S
S
A
R
T
P
S
S
P
H
K
K
F
S
Site 163
S1125
S
S
A
R
T
P
S
S
P
H
K
K
F
S
P
Site 164
S1131
S
S
P
H
K
K
F
S
P
S
H
S
S
M
S
Site 165
S1133
P
H
K
K
F
S
P
S
H
S
S
M
S
H
L
Site 166
S1135
K
K
F
S
P
S
H
S
S
M
S
H
L
E
A
Site 167
S1136
K
F
S
P
S
H
S
S
M
S
H
L
E
A
V
Site 168
S1138
S
P
S
H
S
S
M
S
H
L
E
A
V
S
P
Site 169
S1144
M
S
H
L
E
A
V
S
P
S
D
S
R
G
T
Site 170
S1146
H
L
E
A
V
S
P
S
D
S
R
G
T
S
S
Site 171
S1148
E
A
V
S
P
S
D
S
R
G
T
S
S
S
H
Site 172
T1151
S
P
S
D
S
R
G
T
S
S
S
H
C
R
P
Site 173
S1152
P
S
D
S
R
G
T
S
S
S
H
C
R
P
Q
Site 174
S1153
S
D
S
R
G
T
S
S
S
H
C
R
P
Q
E
Site 175
S1154
D
S
R
G
T
S
S
S
H
C
R
P
Q
E
N
Site 176
S1164
R
P
Q
E
N
I
S
S
R
W
M
V
P
T
S
Site 177
T1170
S
S
R
W
M
V
P
T
S
V
E
R
L
R
E
Site 178
S1171
S
R
W
M
V
P
T
S
V
E
R
L
R
E
G
Site 179
S1180
E
R
L
R
E
G
G
S
I
P
K
V
L
R
S
Site 180
S1187
S
I
P
K
V
L
R
S
S
V
R
V
A
Q
K
Site 181
S1188
I
P
K
V
L
R
S
S
V
R
V
A
Q
K
G
Site 182
S1198
V
A
Q
K
G
E
P
S
P
T
W
E
S
N
I
Site 183
T1200
Q
K
G
E
P
S
P
T
W
E
S
N
I
T
E
Site 184
T1206
P
T
W
E
S
N
I
T
E
K
D
S
D
P
A
Site 185
S1210
S
N
I
T
E
K
D
S
D
P
A
D
G
E
G
Site 186
T1220
A
D
G
E
G
P
E
T
L
S
S
A
L
S
K
Site 187
S1222
G
E
G
P
E
T
L
S
S
A
L
S
K
G
A
Site 188
S1223
E
G
P
E
T
L
S
S
A
L
S
K
G
A
T
Site 189
S1226
E
T
L
S
S
A
L
S
K
G
A
T
V
Y
S
Site 190
T1230
S
A
L
S
K
G
A
T
V
Y
S
P
S
R
Y
Site 191
Y1232
L
S
K
G
A
T
V
Y
S
P
S
R
Y
S
Y
Site 192
S1233
S
K
G
A
T
V
Y
S
P
S
R
Y
S
Y
Q
Site 193
S1238
V
Y
S
P
S
R
Y
S
Y
Q
L
L
Q
C
D
Site 194
Y1239
Y
S
P
S
R
Y
S
Y
Q
L
L
Q
C
D
S
Site 195
S1246
Y
Q
L
L
Q
C
D
S
P
R
T
E
S
Q
S
Site 196
T1249
L
Q
C
D
S
P
R
T
E
S
Q
S
L
L
Q
Site 197
S1251
C
D
S
P
R
T
E
S
Q
S
L
L
Q
Q
S
Site 198
S1253
S
P
R
T
E
S
Q
S
L
L
Q
Q
S
S
S
Site 199
S1258
S
Q
S
L
L
Q
Q
S
S
S
P
F
R
G
H
Site 200
S1259
Q
S
L
L
Q
Q
S
S
S
P
F
R
G
H
P
Site 201
S1260
S
L
L
Q
Q
S
S
S
P
F
R
G
H
P
T
Site 202
T1267
S
P
F
R
G
H
P
T
Q
S
P
G
Y
S
Y
Site 203
S1269
F
R
G
H
P
T
Q
S
P
G
Y
S
Y
R
T
Site 204
S1273
P
T
Q
S
P
G
Y
S
Y
R
T
T
A
L
R
Site 205
T1277
P
G
Y
S
Y
R
T
T
A
L
R
P
G
N
P
Site 206
S1286
L
R
P
G
N
P
P
S
H
G
S
S
E
S
S
Site 207
S1289
G
N
P
P
S
H
G
S
S
E
S
S
L
S
S
Site 208
S1290
N
P
P
S
H
G
S
S
E
S
S
L
S
S
T
Site 209
S1292
P
S
H
G
S
S
E
S
S
L
S
S
T
S
Y
Site 210
S1293
S
H
G
S
S
E
S
S
L
S
S
T
S
Y
S
Site 211
S1295
G
S
S
E
S
S
L
S
S
T
S
Y
S
S
P
Site 212
S1296
S
S
E
S
S
L
S
S
T
S
Y
S
S
P
A
Site 213
T1297
S
E
S
S
L
S
S
T
S
Y
S
S
P
A
H
Site 214
S1298
E
S
S
L
S
S
T
S
Y
S
S
P
A
H
P
Site 215
Y1299
S
S
L
S
S
T
S
Y
S
S
P
A
H
P
V
Site 216
S1300
S
L
S
S
T
S
Y
S
S
P
A
H
P
V
S
Site 217
S1301
L
S
S
T
S
Y
S
S
P
A
H
P
V
S
T
Site 218
S1307
S
S
P
A
H
P
V
S
T
D
S
L
A
P
F
Site 219
S1310
A
H
P
V
S
T
D
S
L
A
P
F
T
G
T
Site 220
T1315
T
D
S
L
A
P
F
T
G
T
P
G
Y
F
S
Site 221
T1317
S
L
A
P
F
T
G
T
P
G
Y
F
S
S
Q
Site 222
Y1320
P
F
T
G
T
P
G
Y
F
S
S
Q
P
H
S
Site 223
S1322
T
G
T
P
G
Y
F
S
S
Q
P
H
S
G
N
Site 224
S1323
G
T
P
G
Y
F
S
S
Q
P
H
S
G
N
S
Site 225
S1327
Y
F
S
S
Q
P
H
S
G
N
S
T
G
S
N
Site 226
S1330
S
Q
P
H
S
G
N
S
T
G
S
N
L
P
R
Site 227
T1331
Q
P
H
S
G
N
S
T
G
S
N
L
P
R
R
Site 228
S1333
H
S
G
N
S
T
G
S
N
L
P
R
R
S
C
Site 229
S1339
G
S
N
L
P
R
R
S
C
P
S
S
A
A
S
Site 230
S1342
L
P
R
R
S
C
P
S
S
A
A
S
P
T
L
Site 231
S1343
P
R
R
S
C
P
S
S
A
A
S
P
T
L
Q
Site 232
S1346
S
C
P
S
S
A
A
S
P
T
L
Q
G
P
S
Site 233
T1348
P
S
S
A
A
S
P
T
L
Q
G
P
S
D
S
Site 234
S1353
S
P
T
L
Q
G
P
S
D
S
P
T
S
D
S
Site 235
S1355
T
L
Q
G
P
S
D
S
P
T
S
D
S
V
S
Site 236
T1357
Q
G
P
S
D
S
P
T
S
D
S
V
S
Q
S
Site 237
S1358
G
P
S
D
S
P
T
S
D
S
V
S
Q
S
S
Site 238
S1360
S
D
S
P
T
S
D
S
V
S
Q
S
S
T
G
Site 239
S1362
S
P
T
S
D
S
V
S
Q
S
S
T
G
T
L
Site 240
S1364
T
S
D
S
V
S
Q
S
S
T
G
T
L
S
S
Site 241
S1365
S
D
S
V
S
Q
S
S
T
G
T
L
S
S
T
Site 242
T1366
D
S
V
S
Q
S
S
T
G
T
L
S
S
T
S
Site 243
T1368
V
S
Q
S
S
T
G
T
L
S
S
T
S
F
P
Site 244
S1370
Q
S
S
T
G
T
L
S
S
T
S
F
P
Q
N
Site 245
S1371
S
S
T
G
T
L
S
S
T
S
F
P
Q
N
S
Site 246
T1372
S
T
G
T
L
S
S
T
S
F
P
Q
N
S
R
Site 247
S1373
T
G
T
L
S
S
T
S
F
P
Q
N
S
R
S
Site 248
S1378
S
T
S
F
P
Q
N
S
R
S
S
L
P
S
D
Site 249
S1380
S
F
P
Q
N
S
R
S
S
L
P
S
D
L
R
Site 250
S1381
F
P
Q
N
S
R
S
S
L
P
S
D
L
R
T
Site 251
S1384
N
S
R
S
S
L
P
S
D
L
R
T
I
S
L
Site 252
T1388
S
L
P
S
D
L
R
T
I
S
L
P
S
A
G
Site 253
S1390
P
S
D
L
R
T
I
S
L
P
S
A
G
Q
S
Site 254
S1397
S
L
P
S
A
G
Q
S
A
V
Y
Q
A
S
R
Site 255
Y1400
S
A
G
Q
S
A
V
Y
Q
A
S
R
V
S
A
Site 256
S1403
Q
S
A
V
Y
Q
A
S
R
V
S
A
V
S
N
Site 257
S1406
V
Y
Q
A
S
R
V
S
A
V
S
N
S
Q
H
Site 258
S1409
A
S
R
V
S
A
V
S
N
S
Q
H
Y
P
H
Site 259
S1411
R
V
S
A
V
S
N
S
Q
H
Y
P
H
R
G
Site 260
Y1414
A
V
S
N
S
Q
H
Y
P
H
R
G
S
G
G
Site 261
S1433
R
L
Q
P
L
Q
G
S
G
V
K
T
Q
T
G
Site 262
T1437
L
Q
G
S
G
V
K
T
Q
T
G
L
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation