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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM2
Full Name:
Tripartite motif-containing protein 2
Alias:
KIAA0517; RING finger protein 86; Rnf86; Tripartite motif-containing 2
Type:
Intracellular, Cytoplasm protein
Mass (Da):
81530
Number AA:
744
UniProt ID:
Q9C040
International Prot ID:
IPI00153011
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
E
G
T
N
I
P
S
P
V
V
R
Q
I
D
Site 2
Y30
C
S
I
C
L
E
R
Y
K
N
P
K
V
L
P
Site 3
Y50
C
E
R
C
L
Q
N
Y
I
P
A
H
S
L
T
Site 4
S59
P
A
H
S
L
T
L
S
C
P
V
C
R
Q
T
Site 5
T66
S
C
P
V
C
R
Q
T
S
I
L
P
E
K
G
Site 6
S67
C
P
V
C
R
Q
T
S
I
L
P
E
K
G
V
Site 7
T93
L
M
D
V
L
Q
R
T
P
G
S
N
A
E
E
Site 8
S96
V
L
Q
R
T
P
G
S
N
A
E
E
S
S
I
Site 9
S117
V
A
A
G
K
P
L
S
C
P
N
H
D
G
N
Site 10
Y129
D
G
N
V
M
E
F
Y
C
Q
S
C
E
T
A
Site 11
S181
K
R
L
P
E
I
D
S
A
L
Q
F
I
S
E
Site 12
S187
D
S
A
L
Q
F
I
S
E
I
I
H
Q
L
T
Site 13
S206
S
I
V
D
D
I
H
S
T
F
D
E
L
Q
K
Site 14
T207
I
V
D
D
I
H
S
T
F
D
E
L
Q
K
T
Site 15
T214
T
F
D
E
L
Q
K
T
L
N
V
R
K
S
V
Site 16
S220
K
T
L
N
V
R
K
S
V
L
L
M
E
L
E
Site 17
S239
L
K
H
K
V
L
Q
S
Q
L
D
T
L
L
Q
Site 18
T243
V
L
Q
S
Q
L
D
T
L
L
Q
G
Q
E
S
Site 19
S250
T
L
L
Q
G
Q
E
S
I
K
S
C
S
N
F
Site 20
S253
Q
G
Q
E
S
I
K
S
C
S
N
F
T
A
Q
Site 21
S311
E
T
E
G
L
K
K
S
I
H
N
L
G
T
I
Site 22
T338
T
G
E
G
L
R
Q
T
I
I
G
Q
P
M
S
Site 23
T349
Q
P
M
S
V
T
I
T
T
K
D
K
D
G
E
Site 24
T360
K
D
G
E
L
C
K
T
G
N
A
Y
L
T
A
Site 25
T366
K
T
G
N
A
Y
L
T
A
E
L
S
T
P
D
Site 26
S370
A
Y
L
T
A
E
L
S
T
P
D
G
S
V
A
Site 27
T371
Y
L
T
A
E
L
S
T
P
D
G
S
V
A
D
Site 28
S375
E
L
S
T
P
D
G
S
V
A
D
G
E
I
L
Site 29
Y393
N
G
T
Y
E
F
L
Y
T
V
Q
K
E
G
D
Site 30
T394
G
T
Y
E
F
L
Y
T
V
Q
K
E
G
D
F
Site 31
T402
V
Q
K
E
G
D
F
T
L
S
L
R
L
Y
D
Site 32
S404
K
E
G
D
F
T
L
S
L
R
L
Y
D
Q
H
Site 33
Y408
F
T
L
S
L
R
L
Y
D
Q
H
I
R
G
S
Site 34
S415
Y
D
Q
H
I
R
G
S
P
F
K
L
K
V
I
Site 35
S424
F
K
L
K
V
I
R
S
A
D
V
S
P
T
T
Site 36
S428
V
I
R
S
A
D
V
S
P
T
T
E
G
V
K
Site 37
T431
S
A
D
V
S
P
T
T
E
G
V
K
R
R
V
Site 38
S440
G
V
K
R
R
V
K
S
P
G
S
G
H
V
K
Site 39
S443
R
R
V
K
S
P
G
S
G
H
V
K
Q
K
A
Site 40
S456
K
A
V
K
R
P
A
S
M
Y
S
T
G
K
R
Site 41
Y458
V
K
R
P
A
S
M
Y
S
T
G
K
R
K
E
Site 42
S459
K
R
P
A
S
M
Y
S
T
G
K
R
K
E
N
Site 43
T460
R
P
A
S
M
Y
S
T
G
K
R
K
E
N
P
Site 44
T478
D
L
I
F
R
V
G
T
K
G
R
N
K
G
E
Site 45
S521
S
N
D
G
Q
F
K
S
R
F
G
I
R
G
R
Site 46
S529
R
F
G
I
R
G
R
S
P
G
Q
L
Q
R
P
Site 47
T537
P
G
Q
L
Q
R
P
T
G
V
A
V
H
P
S
Site 48
S558
D
Y
D
N
K
W
V
S
I
F
S
S
D
G
K
Site 49
S562
K
W
V
S
I
F
S
S
D
G
K
F
K
T
K
Site 50
T568
S
S
D
G
K
F
K
T
K
I
G
S
G
K
L
Site 51
S572
K
F
K
T
K
I
G
S
G
K
L
M
G
P
K
Site 52
S582
L
M
G
P
K
G
V
S
V
D
R
N
G
H
I
Site 53
S614
K
I
V
T
R
F
G
S
R
G
N
G
D
R
Q
Site 54
S661
E
F
M
L
K
F
G
S
N
G
E
G
N
G
Q
Site 55
S701
Q
V
F
D
G
S
G
S
F
L
S
Y
I
N
T
Site 56
S704
D
G
S
G
S
F
L
S
Y
I
N
T
S
A
D
Site 57
Y705
G
S
G
S
F
L
S
Y
I
N
T
S
A
D
P
Site 58
T708
S
F
L
S
Y
I
N
T
S
A
D
P
L
Y
G
Site 59
Y714
N
T
S
A
D
P
L
Y
G
P
Q
G
L
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation