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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TM6SF2
Full Name:
Transmembrane 6 superfamily member 2
Alias:
Lpr4; TM6S2
Type:
Mass (Da):
39570
Number AA:
UniProt ID:
Q9BZW4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y96
V
V
G
F
M
E
F
Y
T
K
E
G
E
P
Y
Site 2
T97
V
G
F
M
E
F
Y
T
K
E
G
E
P
Y
L
Site 3
Y103
Y
T
K
E
G
E
P
Y
L
R
T
A
H
G
V
Site 4
T106
E
G
E
P
Y
L
R
T
A
H
G
V
F
I
C
Site 5
Y114
A
H
G
V
F
I
C
Y
W
D
G
T
V
H
Y
Site 6
Y124
G
T
V
H
Y
L
L
Y
L
A
M
A
G
A
I
Site 7
Y137
A
I
C
R
R
K
R
Y
R
N
F
G
L
Y
W
Site 8
Y143
R
Y
R
N
F
G
L
Y
W
L
G
S
F
A
M
Site 9
Y164
T
G
N
I
L
G
K
Y
S
S
E
I
R
P
A
Site 10
S165
G
N
I
L
G
K
Y
S
S
E
I
R
P
A
F
Site 11
S166
N
I
L
G
K
Y
S
S
E
I
R
P
A
F
F
Site 12
S191
W
A
G
M
K
V
F
S
Q
P
R
A
L
T
R
Site 13
T197
F
S
Q
P
R
A
L
T
R
C
T
A
N
M
V
Site 14
T200
P
R
A
L
T
R
C
T
A
N
M
V
Q
E
E
Site 15
Y250
P
T
D
A
C
F
V
Y
I
Y
Q
Y
E
P
Y
Site 16
Y252
D
A
C
F
V
Y
I
Y
Q
Y
E
P
Y
L
R
Site 17
Y257
Y
I
Y
Q
Y
E
P
Y
L
R
D
P
V
A
Y
Site 18
Y264
Y
L
R
D
P
V
A
Y
P
K
V
Q
M
L
M
Site 19
T322
G
A
S
M
H
L
R
T
P
F
T
Y
R
C
L
Site 20
Y326
H
L
R
T
P
F
T
Y
R
C
L
Q
W
P
A
Site 21
S341
F
F
H
Q
P
P
P
S
D
P
L
A
L
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation