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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRNKL1
Full Name:
Crooked neck-like protein 1
Alias:
CGI-201; CLF; CRN; Crn, crooked neck-like 1; CRNL1; Crooked neck; Crooked neck (Crn)-like 1; Crooked neck homolog; Crooked neck homologue; Crooked neck pre-mRNA splicing factor-like 1; MSTP021; SYF3
Type:
RNA processing
Mass (Da):
100452
Number AA:
848
UniProt ID:
Q9BZJ0
International Prot ID:
IPI00177437
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000245
GO:0006139
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
A
T
V
E
N
L
T
Site 2
T9
T
A
T
V
E
N
L
T
F
Q
K
D
T
L
G
Site 3
T23
G
N
A
V
D
K
N
T
S
R
L
E
L
R
S
Site 4
S24
N
A
V
D
K
N
T
S
R
L
E
L
R
S
Y
Site 5
S30
T
S
R
L
E
L
R
S
Y
S
L
A
G
R
H
Site 6
Y31
S
R
L
E
L
R
S
Y
S
L
A
G
R
H
G
Site 7
S32
R
L
E
L
R
S
Y
S
L
A
G
R
H
G
S
Site 8
S48
E
P
L
V
L
A
W
S
S
Q
F
R
R
L
T
Site 9
S49
P
L
V
L
A
W
S
S
Q
F
R
R
L
T
W
Site 10
T55
S
S
Q
F
R
R
L
T
W
G
C
A
L
D
A
Site 11
S72
R
S
P
C
V
A
A
S
Q
H
G
V
T
H
L
Site 12
S82
G
V
T
H
L
I
R
S
S
R
T
P
H
S
T
Site 13
S83
V
T
H
L
I
R
S
S
R
T
P
H
S
T
R
Site 14
T85
H
L
I
R
S
S
R
T
P
H
S
T
R
C
R
Site 15
S88
R
S
S
R
T
P
H
S
T
R
C
R
K
E
D
Site 16
T89
S
S
R
T
P
H
S
T
R
C
R
K
E
D
A
Site 17
S107
H
H
G
N
G
A
A
S
V
T
A
Q
A
R
G
Site 18
S117
A
Q
A
R
G
Q
R
S
V
L
Q
V
P
L
P
Site 19
S138
F
S
E
S
F
V
V
S
V
S
S
Q
S
R
F
Site 20
S141
S
F
V
V
S
V
S
S
Q
S
R
F
L
A
S
Site 21
S143
V
V
S
V
S
S
Q
S
R
F
L
A
S
V
P
Site 22
S148
S
Q
S
R
F
L
A
S
V
P
G
T
G
V
Q
Site 23
S157
P
G
T
G
V
Q
R
S
T
A
A
D
M
A
A
Site 24
T158
G
T
G
V
Q
R
S
T
A
A
D
M
A
A
S
Site 25
T190
A
P
A
E
V
Q
I
T
A
E
Q
L
L
R
E
Site 26
Y223
D
E
E
E
L
N
D
Y
K
L
R
K
R
K
T
Site 27
T230
Y
K
L
R
K
R
K
T
F
E
D
N
I
R
K
Site 28
Y248
V
I
S
N
W
I
K
Y
A
Q
W
E
E
S
L
Site 29
S263
K
E
I
Q
R
A
R
S
I
Y
E
R
A
L
D
Site 30
Y265
I
Q
R
A
R
S
I
Y
E
R
A
L
D
V
D
Site 31
Y273
E
R
A
L
D
V
D
Y
R
N
I
T
L
W
L
Site 32
T277
D
V
D
Y
R
N
I
T
L
W
L
K
Y
A
E
Site 33
Y282
N
I
T
L
W
L
K
Y
A
E
M
E
M
K
N
Site 34
T304
N
I
W
D
R
A
I
T
T
L
P
R
V
N
Q
Site 35
T305
I
W
D
R
A
I
T
T
L
P
R
V
N
Q
F
Site 36
Y349
E
E
Q
A
W
H
S
Y
I
N
F
E
L
R
Y
Site 37
T364
K
E
V
D
R
A
R
T
I
Y
E
R
F
V
L
Site 38
Y366
V
D
R
A
R
T
I
Y
E
R
F
V
L
V
H
Site 39
Y382
D
V
K
N
W
I
K
Y
A
R
F
E
E
K
H
Site 40
Y391
R
F
E
E
K
H
A
Y
F
A
H
A
R
K
V
Site 41
Y399
F
A
H
A
R
K
V
Y
E
R
A
V
E
F
F
Site 42
Y416
E
H
M
D
E
H
L
Y
V
A
F
A
K
F
E
Site 43
Y436
F
E
R
V
R
V
I
Y
K
Y
A
L
D
R
I
Site 44
Y438
R
V
R
V
I
Y
K
Y
A
L
D
R
I
S
K
Site 45
S444
K
Y
A
L
D
R
I
S
K
Q
D
A
Q
E
L
Site 46
S474
G
I
E
D
I
I
V
S
K
R
R
F
Q
Y
E
Site 47
Y480
V
S
K
R
R
F
Q
Y
E
E
E
V
K
A
N
Site 48
Y491
V
K
A
N
P
H
N
Y
D
A
W
F
D
Y
L
Site 49
Y497
N
Y
D
A
W
F
D
Y
L
R
L
V
E
S
D
Site 50
S503
D
Y
L
R
L
V
E
S
D
A
E
A
E
A
V
Site 51
Y514
A
E
A
V
R
E
V
Y
E
R
A
I
A
N
V
Site 52
Y543
L
W
I
N
Y
A
L
Y
E
E
L
E
A
K
D
Site 53
Y558
P
E
R
T
R
Q
V
Y
Q
A
S
L
E
L
I
Site 54
S561
T
R
Q
V
Y
Q
A
S
L
E
L
I
P
H
K
Site 55
S590
E
I
R
Q
K
N
L
S
L
A
R
R
A
L
G
Site 56
T598
L
A
R
R
A
L
G
T
S
I
G
K
C
P
K
Site 57
S599
A
R
R
A
L
G
T
S
I
G
K
C
P
K
N
Site 58
Y629
F
D
R
C
R
K
L
Y
E
K
F
L
E
F
G
Site 59
Y663
I
D
R
A
R
A
I
Y
E
L
A
I
S
Q
P
Site 60
T692
F
E
I
E
Q
E
E
T
E
R
T
R
N
L
Y
Site 61
Y699
T
E
R
T
R
N
L
Y
R
R
L
L
Q
R
T
Site 62
S721
S
F
A
Q
F
E
L
S
S
G
K
E
G
S
L
Site 63
S727
L
S
S
G
K
E
G
S
L
T
K
C
R
Q
I
Site 64
T729
S
G
K
E
G
S
L
T
K
C
R
Q
I
Y
E
Site 65
Y735
L
T
K
C
R
Q
I
Y
E
E
A
N
K
T
M
Site 66
T741
I
Y
E
E
A
N
K
T
M
R
N
C
E
E
K
Site 67
S757
E
R
L
M
L
L
E
S
W
R
S
F
E
E
E
Site 68
S760
M
L
L
E
S
W
R
S
F
E
E
E
F
G
T
Site 69
T767
S
F
E
E
E
F
G
T
A
S
D
K
E
R
V
Site 70
T790
K
K
R
R
K
V
Q
T
D
D
G
S
D
A
G
Site 71
S794
K
V
Q
T
D
D
G
S
D
A
G
W
E
E
Y
Site 72
Y801
S
D
A
G
W
E
E
Y
F
D
Y
I
F
P
E
Site 73
Y804
G
W
E
E
Y
F
D
Y
I
F
P
E
D
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation