PhosphoNET

           
Protein Info 
   
Short Name:  DPH1
Full Name:  Diphthamide biosynthesis protein 1
Alias:  DPH1 homolog;Diphthamide biosynthesis protein 2 homolog-like 1;Ovarian cancer-associated gene 1 protein
Type: 
Mass (Da):  48805
Number AA:  443
UniProt ID:  Q9BZG8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T162VDIRIDTTHLLDSLR
Site 2S167DTTHLLDSLRLTFPP
Site 3S204LKAEYRVSVPQCKPL
Site 4S212VPQCKPLSPGEILGC
Site 5S221GEILGCTSPRLSKEV
Site 6S225GCTSPRLSKEVEAVV
Site 7Y233KEVEAVVYLGDGRFH
Site 8S243DGRFHLESVMIANPN
Site 9Y254ANPNVPAYRYDPYSK
Site 10Y256PNVPAYRYDPYSKVL
Site 11Y259PAYRYDPYSKVLSRE
Site 12S260AYRYDPYSKVLSREH
Site 13S264DPYSKVLSREHYDHQ
Site 14Y268KVLSREHYDHQRMQA
Site 15T283ARQEAIATARSAKSW
Site 16T296SWGLILGTLGRQGSP
Site 17S302GTLGRQGSPKILEHL
Site 18S311KILEHLESRLRALGL
Site 19S376AVALRDISWQQPYPM
Site 20Y386QPYPMDFYAGSSLGP
Site 21T395GSSLGPWTVNHGQDR
Site 22S419RGKVQEGSARPPSAV
Site 23S424EGSARPPSAVACEDC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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