KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PUS3
Full Name:
tRNA pseudouridine synthase 3
Alias:
FKSG32; Pseudouridylate synthase 3; TRNA pseudouridine synthase 3; TRNA pseudouridylate synthase 3; TRNA-uridine isomerase 3
Type:
EC 5.4.99.-; RNA processing; Isomerase
Mass (Da):
55650
Number AA:
UniProt ID:
Q9BZE2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
N
D
T
D
R
N
Q
T
E
K
L
L
K
R
V
Site 2
S39
Q
A
K
N
K
E
D
S
N
I
R
E
N
S
A
Site 3
S45
D
S
N
I
R
E
N
S
A
G
A
G
K
T
K
Site 4
T51
N
S
A
G
A
G
K
T
K
R
A
F
D
F
S
Site 5
S58
T
K
R
A
F
D
F
S
A
H
G
R
R
H
V
Site 6
T85
G
F
A
S
Q
E
N
T
N
N
T
I
E
E
K
Site 7
T98
E
K
L
F
E
A
L
T
K
T
R
L
V
E
S
Site 8
T100
L
F
E
A
L
T
K
T
R
L
V
E
S
R
Q
Site 9
T108
R
L
V
E
S
R
Q
T
S
N
Y
H
R
C
G
Site 10
S109
L
V
E
S
R
Q
T
S
N
Y
H
R
C
G
R
Site 11
Y111
E
S
R
Q
T
S
N
Y
H
R
C
G
R
T
D
Site 12
S134
V
I
S
L
D
L
R
S
Q
F
P
R
G
R
D
Site 13
S142
Q
F
P
R
G
R
D
S
E
D
F
N
V
K
E
Site 14
Y160
A
A
A
E
E
I
R
Y
T
H
I
L
N
R
V
Site 15
T161
A
A
E
E
I
R
Y
T
H
I
L
N
R
V
L
Site 16
S185
A
P
V
E
P
S
F
S
A
R
F
S
C
L
E
Site 17
S189
P
S
F
S
A
R
F
S
C
L
E
R
T
Y
R
Site 18
T194
R
F
S
C
L
E
R
T
Y
R
Y
F
F
P
R
Site 19
Y195
F
S
C
L
E
R
T
Y
R
Y
F
F
P
R
A
Site 20
Y197
C
L
E
R
T
Y
R
Y
F
F
P
R
A
D
L
Site 21
T208
R
A
D
L
D
I
V
T
M
D
Y
A
A
Q
K
Site 22
Y216
M
D
Y
A
A
Q
K
Y
V
G
T
H
D
F
R
Site 23
S252
Q
V
Q
L
V
G
Q
S
P
G
E
G
R
W
Q
Site 24
Y314
K
N
P
Q
K
P
Q
Y
S
M
A
V
E
F
P
Site 25
S394
E
W
G
N
V
K
P
S
V
I
K
Q
T
S
A
Site 26
T410
V
E
G
V
K
M
R
T
Y
K
P
L
M
D
R
Site 27
Y411
E
G
V
K
M
R
T
Y
K
P
L
M
D
R
P
Site 28
T456
A
K
R
D
C
N
D
T
L
E
E
E
N
T
N
Site 29
T462
D
T
L
E
E
E
N
T
N
L
E
T
P
T
K
Site 30
T466
E
E
N
T
N
L
E
T
P
T
K
R
V
C
V
Site 31
T468
N
T
N
L
E
T
P
T
K
R
V
C
V
D
T
Site 32
T475
T
K
R
V
C
V
D
T
E
I
K
S
I
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation