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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHOBTB2
Full Name:
Rho-related BTB domain-containing protein 2
Alias:
Deleted in breast cancer 2 gene protein;p83
Type:
Mass (Da):
82626
Number AA:
727
UniProt ID:
Q9BYZ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
S
D
M
D
Y
E
R
P
N
V
E
T
Site 2
S77
R
D
V
V
D
D
V
S
V
S
L
R
L
W
D
Site 3
T85
V
S
L
R
L
W
D
T
F
G
D
H
H
K
D
Site 4
Y97
H
K
D
R
R
F
A
Y
G
R
S
D
V
V
V
Site 5
Y146
G
C
Q
L
D
L
R
Y
A
D
L
E
A
V
N
Site 6
Y186
K
E
L
G
I
P
Y
Y
E
T
S
V
V
A
Q
Site 7
S250
I
V
V
P
D
P
P
S
S
S
E
E
C
P
A
Site 8
S251
V
V
P
D
P
P
S
S
S
E
E
C
P
A
H
Site 9
S252
V
P
D
P
P
S
S
S
E
E
C
P
A
H
L
Site 10
Y284
R
I
F
A
H
K
I
Y
L
S
T
S
S
S
K
Site 11
S286
F
A
H
K
I
Y
L
S
T
S
S
S
K
F
Y
Site 12
S288
H
K
I
Y
L
S
T
S
S
S
K
F
Y
D
L
Site 13
Y293
S
T
S
S
S
K
F
Y
D
L
F
L
M
D
L
Site 14
S309
E
G
E
L
G
G
P
S
E
P
G
G
T
H
P
Site 15
T314
G
P
S
E
P
G
G
T
H
P
E
D
H
Q
G
Site 16
S350
A
S
F
D
V
C
E
S
V
D
E
A
G
G
S
Site 17
S357
S
V
D
E
A
G
G
S
G
P
A
G
L
R
A
Site 18
S365
G
P
A
G
L
R
A
S
T
S
D
G
I
L
R
Site 19
T366
P
A
G
L
R
A
S
T
S
D
G
I
L
R
G
Site 20
S367
A
G
L
R
A
S
T
S
D
G
I
L
R
G
N
Site 21
T376
G
I
L
R
G
N
G
T
G
Y
L
P
G
R
G
Site 22
Y378
L
R
G
N
G
T
G
Y
L
P
G
R
G
R
V
Site 23
S387
P
G
R
G
R
V
L
S
S
W
S
R
A
F
V
Site 24
S388
G
R
G
R
V
L
S
S
W
S
R
A
F
V
S
Site 25
S390
G
R
V
L
S
S
W
S
R
A
F
V
S
I
Q
Site 26
S395
S
W
S
R
A
F
V
S
I
Q
E
E
M
A
E
Site 27
T406
E
M
A
E
D
P
L
T
Y
K
S
R
L
M
V
Site 28
S420
V
V
V
K
M
D
S
S
I
Q
P
G
P
F
R
Site 29
Y432
P
F
R
A
V
L
K
Y
L
Y
T
G
E
L
D
Site 30
Y434
R
A
V
L
K
Y
L
Y
T
G
E
L
D
E
N
Site 31
T435
A
V
L
K
Y
L
Y
T
G
E
L
D
E
N
E
Site 32
T487
K
A
F
H
V
R
R
T
N
R
V
K
E
C
L
Site 33
T503
K
G
T
F
S
D
V
T
F
I
L
D
D
G
T
Site 34
S537
G
G
P
F
V
E
S
S
T
R
E
V
V
F
P
Site 35
Y545
T
R
E
V
V
F
P
Y
T
S
K
S
C
M
R
Site 36
S566
Y
T
G
M
F
T
S
S
P
D
L
D
D
M
K
Site 37
S654
P
R
D
M
K
A
M
S
P
E
N
Q
E
Y
F
Site 38
Y660
M
S
P
E
N
Q
E
Y
F
E
K
H
R
W
P
Site 39
Y678
Y
L
K
E
E
D
H
Y
Q
R
A
R
K
E
R
Site 40
Y690
K
E
R
E
K
E
D
Y
L
H
L
K
R
Q
P
Site 41
S706
R
R
W
L
F
W
N
S
P
S
S
P
S
S
S
Site 42
S708
W
L
F
W
N
S
P
S
S
P
S
S
S
A
A
Site 43
S709
L
F
W
N
S
P
S
S
P
S
S
S
A
A
S
Site 44
S711
W
N
S
P
S
S
P
S
S
S
A
A
S
S
S
Site 45
S712
N
S
P
S
S
P
S
S
S
A
A
S
S
S
S
Site 46
S713
S
P
S
S
P
S
S
S
A
A
S
S
S
S
P
Site 47
S716
S
P
S
S
S
A
A
S
S
S
S
P
S
S
S
Site 48
S717
P
S
S
S
A
A
S
S
S
S
P
S
S
S
S
Site 49
S718
S
S
S
A
A
S
S
S
S
P
S
S
S
S
A
Site 50
S719
S
S
A
A
S
S
S
S
P
S
S
S
S
A
V
Site 51
S721
A
A
S
S
S
S
P
S
S
S
S
A
V
V
_
Site 52
S722
A
S
S
S
S
P
S
S
S
S
A
V
V
_
_
Site 53
S723
S
S
S
S
P
S
S
S
S
A
V
V
_
_
_
Site 54
S724
S
S
S
P
S
S
S
S
A
V
V
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation