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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STK33
Full Name:
Serine/threonine-protein kinase 33
Alias:
EC 2.7.11.1; FLJ35932
Type:
Protein-serine kinase, CAMK group, CAMK-Unique family
Mass (Da):
57831
Number AA:
514
UniProt ID:
Q9BYT3
International Prot ID:
IPI00302351
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
S
G
L
D
K
K
S
T
K
C
P
D
C
S
Site 2
T11
S
G
L
D
K
K
S
T
K
C
P
D
C
S
S
Site 3
S18
T
K
C
P
D
C
S
S
A
S
Q
K
D
V
L
Site 4
S47
V
E
M
S
Q
T
S
S
I
G
S
A
E
S
L
Site 5
S53
S
S
I
G
S
A
E
S
L
I
S
L
E
R
K
Site 6
S56
G
S
A
E
S
L
I
S
L
E
R
K
K
E
K
Site 7
T70
K
N
I
N
R
D
I
T
S
R
K
D
L
P
S
Site 8
S71
N
I
N
R
D
I
T
S
R
K
D
L
P
S
R
Site 9
S77
T
S
R
K
D
L
P
S
R
T
S
N
V
E
R
Site 10
S80
K
D
L
P
S
R
T
S
N
V
E
R
K
A
S
Site 11
S87
S
N
V
E
R
K
A
S
Q
Q
Q
W
G
R
G
Site 12
T97
Q
W
G
R
G
N
F
T
E
G
K
V
P
H
I
Site 13
S154
V
N
K
E
K
A
G
S
S
A
V
K
L
L
E
Site 14
S155
N
K
E
K
A
G
S
S
A
V
K
L
L
E
R
Site 15
S169
R
E
V
N
I
L
K
S
V
K
H
E
H
I
I
Site 16
T184
H
L
E
Q
V
F
E
T
P
K
K
M
Y
L
V
Site 17
Y189
F
E
T
P
K
K
M
Y
L
V
M
E
L
C
E
Site 18
S211
L
D
R
K
G
H
F
S
E
N
E
T
R
W
I
Site 19
S248
L
E
N
I
M
V
K
S
S
L
I
D
D
N
N
Site 20
S249
E
N
I
M
V
K
S
S
L
I
D
D
N
N
E
Site 21
S276
A
V
K
K
Q
S
R
S
E
A
M
L
Q
A
T
Site 22
Y300
E
V
I
S
A
H
D
Y
S
Q
Q
C
D
I
W
Site 23
S326
G
E
P
P
F
L
A
S
S
E
E
K
L
F
E
Site 24
S327
E
P
P
F
L
A
S
S
E
E
K
L
F
E
L
Site 25
S356
S
I
S
D
C
A
K
S
V
L
K
Q
L
M
K
Site 26
T371
V
D
P
A
H
R
I
T
A
K
E
L
L
D
N
Site 27
T382
L
L
D
N
Q
W
L
T
G
N
K
L
S
S
V
Site 28
S387
W
L
T
G
N
K
L
S
S
V
R
P
T
N
V
Site 29
S388
L
T
G
N
K
L
S
S
V
R
P
T
N
V
L
Site 30
T392
K
L
S
S
V
R
P
T
N
V
L
E
M
M
K
Site 31
S407
E
W
K
N
N
P
E
S
V
E
E
N
T
T
E
Site 32
T413
E
S
V
E
E
N
T
T
E
E
K
N
K
P
S
Site 33
S420
T
E
E
K
N
K
P
S
T
E
E
K
L
K
S
Site 34
T421
E
E
K
N
K
P
S
T
E
E
K
L
K
S
Y
Site 35
S427
S
T
E
E
K
L
K
S
Y
Q
P
W
G
N
V
Site 36
Y428
T
E
E
K
L
K
S
Y
Q
P
W
G
N
V
P
Site 37
Y439
G
N
V
P
D
A
N
Y
T
S
D
E
E
E
E
Site 38
S441
V
P
D
A
N
Y
T
S
D
E
E
E
E
K
Q
Site 39
S449
D
E
E
E
E
K
Q
S
T
A
Y
E
K
Q
F
Site 40
T450
E
E
E
E
K
Q
S
T
A
Y
E
K
Q
F
P
Site 41
Y452
E
E
K
Q
S
T
A
Y
E
K
Q
F
P
A
T
Site 42
S468
K
D
N
F
D
M
C
S
S
S
F
T
S
S
K
Site 43
S469
D
N
F
D
M
C
S
S
S
F
T
S
S
K
L
Site 44
S470
N
F
D
M
C
S
S
S
F
T
S
S
K
L
L
Site 45
T472
D
M
C
S
S
S
F
T
S
S
K
L
L
P
A
Site 46
S473
M
C
S
S
S
F
T
S
S
K
L
L
P
A
E
Site 47
T488
I
K
G
E
M
E
K
T
P
V
T
P
S
Q
G
Site 48
T491
E
M
E
K
T
P
V
T
P
S
Q
G
T
A
T
Site 49
S493
E
K
T
P
V
T
P
S
Q
G
T
A
T
K
Y
Site 50
T496
P
V
T
P
S
Q
G
T
A
T
K
Y
P
A
K
Site 51
T498
T
P
S
Q
G
T
A
T
K
Y
P
A
K
S
G
Site 52
Y500
S
Q
G
T
A
T
K
Y
P
A
K
S
G
A
L
Site 53
S504
A
T
K
Y
P
A
K
S
G
A
L
S
R
T
K
Site 54
S508
P
A
K
S
G
A
L
S
R
T
K
K
K
L
_
Site 55
T510
K
S
G
A
L
S
R
T
K
K
K
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation