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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Wnk3
Full Name:
Serine/threonine-protein kinase WNK3
Alias:
EC 2.7.11.1; KIAA1566; PRKWNK3; Protein kinase, lysine-deficient 3
Type:
Protein-serine kinase, Other group, Wnk family
Mass (Da):
191789
Number AA:
1743
UniProt ID:
Q9BYP7
International Prot ID:
IPI00387112
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
GO:0007243
Phosida
TranscriptoNet
STRING
Kinexus Products
Serine/threonine-protein kinase WNK3 pan-specific antibody AB-NK254-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK254-1#Serine/threonine-protein kinase WNK3 pan-specific antibody AB-NK254-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK254-2#Serine/threonine-protein kinase WNK3 pan-specific antibody AB-NK254-3#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK254-3#Serine/threonine-protein kinase WNK3 (M1-E15, human) peptide - Powder PE-01AZE99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01AZE99#Serine/threonine-protein kinase WNK3 (E31-R145, human) peptide - Powder PE-01AZF80#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01AZF80#Serine/threonine-protein kinase WNK3 (G1773-S1787, human) peptide - Powder PE-01AZG99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01AZG99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
T
D
S
G
D
P
A
S
T
E
D
S
E
K
P
Site 2
S14
D
P
A
S
T
E
D
S
E
K
P
D
G
I
S
Site 3
S21
S
E
K
P
D
G
I
S
F
E
N
R
V
P
Q
Site 4
T34
P
Q
V
A
A
T
L
T
V
E
A
R
L
K
E
Site 5
S44
A
R
L
K
E
K
N
S
T
F
S
A
S
G
E
Site 6
T45
R
L
K
E
K
N
S
T
F
S
A
S
G
E
T
Site 7
S47
K
E
K
N
S
T
F
S
A
S
G
E
T
V
E
Site 8
S62
R
K
R
F
F
R
K
S
V
E
M
T
E
D
D
Site 9
T66
F
R
K
S
V
E
M
T
E
D
D
K
V
A
E
Site 10
S75
D
D
K
V
A
E
S
S
P
K
D
E
R
I
K
Site 11
S95
P
R
V
D
K
L
P
S
N
V
L
R
G
G
Q
Site 12
Y106
R
G
G
Q
E
V
K
Y
E
Q
C
S
K
S
T
Site 13
S110
E
V
K
Y
E
Q
C
S
K
S
T
S
E
I
S
Site 14
S112
K
Y
E
Q
C
S
K
S
T
S
E
I
S
K
D
Site 15
S114
E
Q
C
S
K
S
T
S
E
I
S
K
D
C
F
Site 16
T140
A
E
M
K
A
V
A
T
S
P
S
G
R
F
L
Site 17
S141
E
M
K
A
V
A
T
S
P
S
G
R
F
L
K
Site 18
S143
K
A
V
A
T
S
P
S
G
R
F
L
K
F
D
Site 19
T160
L
G
R
G
A
F
K
T
V
Y
K
G
L
D
T
Site 20
Y162
R
G
A
F
K
T
V
Y
K
G
L
D
T
E
T
Site 21
T184
E
L
Q
D
R
K
L
T
K
A
E
Q
Q
R
F
Site 22
Y210
H
P
N
I
V
R
F
Y
D
S
W
E
S
I
L
Site 23
S212
N
I
V
R
F
Y
D
S
W
E
S
I
L
K
G
Site 24
T234
T
E
L
M
T
S
G
T
L
K
T
Y
L
K
R
Site 25
Y238
T
S
G
T
L
K
T
Y
L
K
R
F
K
V
M
Site 26
T266
K
G
L
Q
F
L
H
T
R
T
P
P
I
I
H
Site 27
T268
L
Q
F
L
H
T
R
T
P
P
I
I
H
R
D
Site 28
T299
I
G
D
L
G
L
A
T
L
M
R
T
S
F
A
Site 29
T303
G
L
A
T
L
M
R
T
S
F
A
K
S
V
I
Site 30
S304
L
A
T
L
M
R
T
S
F
A
K
S
V
I
G
Site 31
S308
M
R
T
S
F
A
K
S
V
I
G
T
P
E
F
Site 32
Y325
P
E
M
Y
E
E
H
Y
D
E
S
V
D
V
Y
Site 33
Y346
L
E
M
A
T
S
E
Y
P
Y
S
E
C
Q
N
Site 34
S349
A
T
S
E
Y
P
Y
S
E
C
Q
N
A
A
Q
Site 35
T362
A
Q
I
Y
R
K
V
T
S
G
I
K
P
A
S
Site 36
S369
T
S
G
I
K
P
A
S
F
N
K
V
T
D
P
Site 37
S391
G
C
I
R
Q
N
K
S
E
R
L
S
I
R
D
Site 38
S395
Q
N
K
S
E
R
L
S
I
R
D
L
L
N
H
Site 39
S422
L
A
E
E
D
D
C
S
N
S
S
L
A
L
R
Site 40
S424
E
E
D
D
C
S
N
S
S
L
A
L
R
L
W
Site 41
S425
E
D
D
C
S
N
S
S
L
A
L
R
L
W
V
Site 42
S451
D
N
E
A
I
E
F
S
F
N
L
E
T
D
T
Site 43
T456
E
F
S
F
N
L
E
T
D
T
P
E
E
V
A
Site 44
T458
S
F
N
L
E
T
D
T
P
E
E
V
A
Y
E
Site 45
Y464
D
T
P
E
E
V
A
Y
E
M
V
K
S
G
F
Site 46
S469
V
A
Y
E
M
V
K
S
G
F
F
H
E
S
D
Site 47
S475
K
S
G
F
F
H
E
S
D
S
K
A
V
A
K
Site 48
S477
G
F
F
H
E
S
D
S
K
A
V
A
K
S
I
Site 49
S483
D
S
K
A
V
A
K
S
I
R
D
R
V
T
P
Site 50
T489
K
S
I
R
D
R
V
T
P
I
K
K
T
R
E
Site 51
T494
R
V
T
P
I
K
K
T
R
E
K
K
P
A
G
Site 52
S509
C
L
E
E
R
R
D
S
Q
C
K
S
M
G
N
Site 53
S513
R
R
D
S
Q
C
K
S
M
G
N
V
F
P
Q
Site 54
T525
F
P
Q
P
Q
N
T
T
L
P
L
A
P
A
Q
Site 55
T541
T
G
A
E
C
E
E
T
E
V
D
Q
H
V
R
Site 56
S561
R
K
P
Q
Q
H
C
S
S
V
T
G
D
N
L
Site 57
S575
L
S
E
A
G
A
A
S
V
I
H
S
D
T
S
Site 58
S579
G
A
A
S
V
I
H
S
D
T
S
S
Q
P
S
Site 59
T581
A
S
V
I
H
S
D
T
S
S
Q
P
S
V
A
Site 60
S582
S
V
I
H
S
D
T
S
S
Q
P
S
V
A
Y
Site 61
S583
V
I
H
S
D
T
S
S
Q
P
S
V
A
Y
S
Site 62
S586
S
D
T
S
S
Q
P
S
V
A
Y
S
S
N
Q
Site 63
S590
S
Q
P
S
V
A
Y
S
S
N
Q
T
M
G
S
Site 64
T594
V
A
Y
S
S
N
Q
T
M
G
S
Q
M
V
S
Site 65
S597
S
S
N
Q
T
M
G
S
Q
M
V
S
N
I
P
Site 66
S601
T
M
G
S
Q
M
V
S
N
I
P
Q
A
E
V
Site 67
S617
V
P
G
Q
I
Y
S
S
Q
Q
L
V
G
H
Y
Site 68
Y624
S
Q
Q
L
V
G
H
Y
Q
Q
V
S
G
L
Q
Site 69
T671
Q
P
Q
V
S
P
L
T
V
Q
K
V
P
Q
I
Site 70
S682
V
P
Q
I
K
P
V
S
Q
P
V
G
A
E
Q
Site 71
S701
L
K
P
D
L
V
R
S
L
N
Q
D
V
A
T
Site 72
S714
A
T
T
K
E
N
V
S
S
P
D
N
P
S
G
Site 73
S715
T
T
K
E
N
V
S
S
P
D
N
P
S
G
N
Site 74
S720
V
S
S
P
D
N
P
S
G
N
G
K
Q
D
R
Site 75
S734
R
I
K
Q
R
R
A
S
C
P
R
P
E
K
G
Site 76
T747
K
G
T
K
F
Q
L
T
V
L
Q
V
S
T
S
Site 77
Y788
A
P
E
D
I
A
D
Y
M
V
E
D
N
F
V
Site 78
T828
H
F
A
T
E
R
A
T
G
V
D
S
I
T
V
Site 79
S832
E
R
A
T
G
V
D
S
I
T
V
D
S
N
S
Site 80
T834
A
T
G
V
D
S
I
T
V
D
S
N
S
S
Q
Site 81
S837
V
D
S
I
T
V
D
S
N
S
S
Q
T
G
S
Site 82
S839
S
I
T
V
D
S
N
S
S
Q
T
G
S
S
E
Site 83
S840
I
T
V
D
S
N
S
S
Q
T
G
S
S
E
Q
Site 84
S844
S
N
S
S
Q
T
G
S
S
E
Q
V
Q
I
N
Site 85
S852
S
E
Q
V
Q
I
N
S
T
S
T
Q
T
S
N
Site 86
S854
Q
V
Q
I
N
S
T
S
T
Q
T
S
N
E
S
Site 87
S858
N
S
T
S
T
Q
T
S
N
E
S
A
P
Q
S
Site 88
S861
S
T
Q
T
S
N
E
S
A
P
Q
S
S
P
V
Site 89
S865
S
N
E
S
A
P
Q
S
S
P
V
G
R
W
R
Site 90
S866
N
E
S
A
P
Q
S
S
P
V
G
R
W
R
F
Site 91
T884
Q
T
I
R
N
R
E
T
Q
S
P
P
S
L
Q
Site 92
S886
I
R
N
R
E
T
Q
S
P
P
S
L
Q
H
S
Site 93
S889
R
E
T
Q
S
P
P
S
L
Q
H
S
M
S
A
Site 94
S893
S
P
P
S
L
Q
H
S
M
S
A
V
P
G
R
Site 95
S895
P
S
L
Q
H
S
M
S
A
V
P
G
R
H
P
Site 96
S905
P
G
R
H
P
L
P
S
P
K
N
T
S
N
K
Site 97
T909
P
L
P
S
P
K
N
T
S
N
K
E
I
S
R
Site 98
T918
N
K
E
I
S
R
D
T
L
L
T
I
E
N
N
Site 99
T921
I
S
R
D
T
L
L
T
I
E
N
N
P
C
H
Site 100
S934
C
H
R
A
L
F
T
S
K
S
E
H
K
D
V
Site 101
S936
R
A
L
F
T
S
K
S
E
H
K
D
V
V
D
Site 102
S947
D
V
V
D
G
K
I
S
E
C
A
S
V
E
T
Site 103
S951
G
K
I
S
E
C
A
S
V
E
T
K
Q
P
A
Site 104
Y961
T
K
Q
P
A
I
L
Y
Q
V
E
D
N
R
Q
Site 105
T974
R
Q
I
M
A
P
V
T
N
S
S
S
Y
S
T
Site 106
S976
I
M
A
P
V
T
N
S
S
S
Y
S
T
T
S
Site 107
S977
M
A
P
V
T
N
S
S
S
Y
S
T
T
S
V
Site 108
S978
A
P
V
T
N
S
S
S
Y
S
T
T
S
V
R
Site 109
S980
V
T
N
S
S
S
Y
S
T
T
S
V
R
A
V
Site 110
T981
T
N
S
S
S
Y
S
T
T
S
V
R
A
V
P
Site 111
T982
N
S
S
S
Y
S
T
T
S
V
R
A
V
P
A
Site 112
S983
S
S
S
Y
S
T
T
S
V
R
A
V
P
A
E
Site 113
S1012
Y
P
C
H
Q
T
A
S
Q
A
D
A
L
M
S
Site 114
S1019
S
Q
A
D
A
L
M
S
H
P
G
E
S
T
Q
Site 115
S1024
L
M
S
H
P
G
E
S
T
Q
T
S
G
N
S
Site 116
T1027
H
P
G
E
S
T
Q
T
S
G
N
S
L
T
T
Site 117
S1028
P
G
E
S
T
Q
T
S
G
N
S
L
T
T
L
Site 118
S1031
S
T
Q
T
S
G
N
S
L
T
T
L
A
F
D
Site 119
T1043
A
F
D
Q
K
P
Q
T
L
S
V
Q
Q
P
A
Site 120
S1045
D
Q
K
P
Q
T
L
S
V
Q
Q
P
A
M
D
Site 121
S1057
A
M
D
A
E
F
I
S
Q
E
G
E
T
T
V
Site 122
T1063
I
S
Q
E
G
E
T
T
V
N
T
E
A
S
S
Site 123
T1066
E
G
E
T
T
V
N
T
E
A
S
S
P
K
T
Site 124
S1070
T
V
N
T
E
A
S
S
P
K
T
V
I
P
T
Site 125
T1073
T
E
A
S
S
P
K
T
V
I
P
T
Q
T
P
Site 126
T1077
S
P
K
T
V
I
P
T
Q
T
P
G
L
E
P
Site 127
T1079
K
T
V
I
P
T
Q
T
P
G
L
E
P
T
T
Site 128
T1086
T
P
G
L
E
P
T
T
L
Q
P
T
T
V
L
Site 129
T1091
P
T
T
L
Q
P
T
T
V
L
E
S
D
G
E
Site 130
S1095
Q
P
T
T
V
L
E
S
D
G
E
R
P
P
K
Site 131
T1112
F
A
D
N
R
I
K
T
L
D
E
K
L
R
N
Site 132
Y1122
E
K
L
R
N
L
L
Y
Q
E
H
S
I
S
S
Site 133
S1126
N
L
L
Y
Q
E
H
S
I
S
S
I
Y
P
E
Site 134
S1128
L
Y
Q
E
H
S
I
S
S
I
Y
P
E
S
Q
Site 135
S1129
Y
Q
E
H
S
I
S
S
I
Y
P
E
S
Q
K
Site 136
Y1131
E
H
S
I
S
S
I
Y
P
E
S
Q
K
D
T
Site 137
S1134
I
S
S
I
Y
P
E
S
Q
K
D
T
Q
S
I
Site 138
T1138
Y
P
E
S
Q
K
D
T
Q
S
I
D
S
P
F
Site 139
S1140
E
S
Q
K
D
T
Q
S
I
D
S
P
F
S
S
Site 140
S1143
K
D
T
Q
S
I
D
S
P
F
S
S
S
A
E
Site 141
S1146
Q
S
I
D
S
P
F
S
S
S
A
E
D
T
L
Site 142
S1147
S
I
D
S
P
F
S
S
S
A
E
D
T
L
S
Site 143
S1148
I
D
S
P
F
S
S
S
A
E
D
T
L
S
C
Site 144
T1152
F
S
S
S
A
E
D
T
L
S
C
P
V
T
E
Site 145
S1171
S
H
C
G
I
K
D
S
P
V
Q
S
P
N
F
Site 146
S1175
I
K
D
S
P
V
Q
S
P
N
F
Q
Q
T
G
Site 147
T1181
Q
S
P
N
F
Q
Q
T
G
S
K
L
L
S
N
Site 148
S1183
P
N
F
Q
Q
T
G
S
K
L
L
S
N
V
A
Site 149
S1187
Q
T
G
S
K
L
L
S
N
V
A
A
S
Q
P
Site 150
S1198
A
S
Q
P
A
N
I
S
V
F
K
R
D
L
N
Site 151
T1208
K
R
D
L
N
V
I
T
S
V
P
S
E
L
C
Site 152
S1220
E
L
C
L
H
E
M
S
S
D
A
S
L
P
G
Site 153
S1221
L
C
L
H
E
M
S
S
D
A
S
L
P
G
D
Site 154
S1224
H
E
M
S
S
D
A
S
L
P
G
D
P
E
A
Site 155
Y1232
L
P
G
D
P
E
A
Y
P
A
A
V
S
S
G
Site 156
T1265
A
P
D
P
I
P
L
T
R
E
S
T
A
D
T
Site 157
S1268
P
I
P
L
T
R
E
S
T
A
D
T
R
A
L
Site 158
T1269
I
P
L
T
R
E
S
T
A
D
T
R
A
L
N
Site 159
T1272
T
R
E
S
T
A
D
T
R
A
L
N
R
C
K
Site 160
S1282
L
N
R
C
K
A
M
S
G
S
F
Q
R
G
R
Site 161
S1284
R
C
K
A
M
S
G
S
F
Q
R
G
R
F
Q
Site 162
T1294
R
G
R
F
Q
V
I
T
I
P
Q
Q
Q
S
A
Site 163
T1304
Q
Q
Q
S
A
K
M
T
S
F
G
I
E
H
I
Site 164
S1305
Q
Q
S
A
K
M
T
S
F
G
I
E
H
I
S
Site 165
S1312
S
F
G
I
E
H
I
S
V
F
S
E
T
N
H
Site 166
S1315
I
E
H
I
S
V
F
S
E
T
N
H
S
S
E
Site 167
S1320
V
F
S
E
T
N
H
S
S
E
E
A
F
I
K
Site 168
T1340
L
V
E
I
E
P
A
T
Q
N
P
K
T
S
F
Site 169
T1345
P
A
T
Q
N
P
K
T
S
F
S
Y
E
K
L
Site 170
S1346
A
T
Q
N
P
K
T
S
F
S
Y
E
K
L
Q
Site 171
S1374
K
Q
G
D
N
F
L
S
F
S
A
A
C
E
T
Site 172
S1384
A
A
C
E
T
D
V
S
S
V
T
P
E
K
E
Site 173
S1385
A
C
E
T
D
V
S
S
V
T
P
E
K
E
F
Site 174
T1387
E
T
D
V
S
S
V
T
P
E
K
E
F
E
E
Site 175
T1395
P
E
K
E
F
E
E
T
S
A
T
G
S
S
M
Site 176
S1396
E
K
E
F
E
E
T
S
A
T
G
S
S
M
Q
Site 177
T1398
E
F
E
E
T
S
A
T
G
S
S
M
Q
S
G
Site 178
S1400
E
E
T
S
A
T
G
S
S
M
Q
S
G
S
E
Site 179
S1404
A
T
G
S
S
M
Q
S
G
S
E
L
L
L
K
Site 180
S1406
G
S
S
M
Q
S
G
S
E
L
L
L
K
E
R
Site 181
T1417
L
K
E
R
E
I
L
T
A
G
K
Q
P
S
S
Site 182
S1423
L
T
A
G
K
Q
P
S
S
D
S
E
F
S
A
Site 183
S1424
T
A
G
K
Q
P
S
S
D
S
E
F
S
A
S
Site 184
S1426
G
K
Q
P
S
S
D
S
E
F
S
A
S
L
A
Site 185
S1429
P
S
S
D
S
E
F
S
A
S
L
A
G
S
G
Site 186
S1431
S
D
S
E
F
S
A
S
L
A
G
S
G
K
S
Site 187
S1435
F
S
A
S
L
A
G
S
G
K
S
V
A
K
T
Site 188
S1438
S
L
A
G
S
G
K
S
V
A
K
T
G
P
E
Site 189
T1442
S
G
K
S
V
A
K
T
G
P
E
S
N
Q
C
Site 190
S1446
V
A
K
T
G
P
E
S
N
Q
C
L
P
H
H
Site 191
Y1458
P
H
H
E
E
Q
A
Y
A
Q
T
Q
S
S
L
Site 192
S1463
Q
A
Y
A
Q
T
Q
S
S
L
F
Y
S
P
S
Site 193
S1464
A
Y
A
Q
T
Q
S
S
L
F
Y
S
P
S
S
Site 194
Y1467
Q
T
Q
S
S
L
F
Y
S
P
S
S
P
M
S
Site 195
S1468
T
Q
S
S
L
F
Y
S
P
S
S
P
M
S
S
Site 196
S1470
S
S
L
F
Y
S
P
S
S
P
M
S
S
D
D
Site 197
S1471
S
L
F
Y
S
P
S
S
P
M
S
S
D
D
E
Site 198
S1474
Y
S
P
S
S
P
M
S
S
D
D
E
S
E
I
Site 199
S1475
S
P
S
S
P
M
S
S
D
D
E
S
E
I
E
Site 200
S1479
P
M
S
S
D
D
E
S
E
I
E
D
E
D
L
Site 201
Y1516
N
K
E
L
Q
E
L
Y
E
R
L
R
S
I
K
Site 202
S1521
E
L
Y
E
R
L
R
S
I
K
D
S
K
T
Q
Site 203
S1525
R
L
R
S
I
K
D
S
K
T
Q
S
T
E
I
Site 204
T1527
R
S
I
K
D
S
K
T
Q
S
T
E
I
P
L
Site 205
S1529
I
K
D
S
K
T
Q
S
T
E
I
P
L
P
P
Site 206
T1530
K
D
S
K
T
Q
S
T
E
I
P
L
P
P
A
Site 207
S1538
E
I
P
L
P
P
A
S
P
R
R
P
R
S
F
Site 208
S1544
A
S
P
R
R
P
R
S
F
K
S
K
L
R
S
Site 209
S1547
R
R
P
R
S
F
K
S
K
L
R
S
R
P
Q
Site 210
S1551
S
F
K
S
K
L
R
S
R
P
Q
S
L
T
H
Site 211
S1555
K
L
R
S
R
P
Q
S
L
T
H
V
D
N
G
Site 212
T1557
R
S
R
P
Q
S
L
T
H
V
D
N
G
I
V
Site 213
S1573
T
D
P
L
C
V
E
S
N
A
A
S
C
Q
Q
Site 214
S1577
C
V
E
S
N
A
A
S
C
Q
Q
S
P
A
S
Site 215
S1581
N
A
A
S
C
Q
Q
S
P
A
S
K
K
G
M
Site 216
S1584
S
C
Q
Q
S
P
A
S
K
K
G
M
F
T
D
Site 217
T1601
H
K
L
V
D
D
W
T
K
E
A
V
G
N
S
Site 218
S1608
T
K
E
A
V
G
N
S
L
I
K
P
S
L
N
Site 219
S1613
G
N
S
L
I
K
P
S
L
N
Q
L
K
Q
S
Site 220
S1620
S
L
N
Q
L
K
Q
S
Q
H
K
L
E
T
E
Site 221
T1636
W
N
K
V
S
E
N
T
P
S
T
M
G
Y
T
Site 222
S1638
K
V
S
E
N
T
P
S
T
M
G
Y
T
S
T
Site 223
T1639
V
S
E
N
T
P
S
T
M
G
Y
T
S
T
W
Site 224
Y1642
N
T
P
S
T
M
G
Y
T
S
T
W
I
S
S
Site 225
S1644
P
S
T
M
G
Y
T
S
T
W
I
S
S
L
S
Site 226
T1645
S
T
M
G
Y
T
S
T
W
I
S
S
L
S
Q
Site 227
S1648
G
Y
T
S
T
W
I
S
S
L
S
Q
I
R
G
Site 228
S1649
Y
T
S
T
W
I
S
S
L
S
Q
I
R
G
A
Site 229
T1659
Q
I
R
G
A
V
P
T
S
L
P
Q
G
L
S
Site 230
S1666
T
S
L
P
Q
G
L
S
L
P
S
F
P
G
P
Site 231
S1669
P
Q
G
L
S
L
P
S
F
P
G
P
L
S
S
Site 232
S1675
P
S
F
P
G
P
L
S
S
Y
G
M
P
H
V
Site 233
S1676
S
F
P
G
P
L
S
S
Y
G
M
P
H
V
C
Site 234
Y1677
F
P
G
P
L
S
S
Y
G
M
P
H
V
C
Q
Site 235
S1707
I
S
G
T
T
Q
Q
S
V
V
I
P
A
Q
S
Site 236
S1730
N
M
Q
A
F
P
T
S
S
V
Q
N
P
A
T
Site 237
S1731
M
Q
A
F
P
T
S
S
V
Q
N
P
A
T
I
Site 238
T1737
S
S
V
Q
N
P
A
T
I
P
P
G
P
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation