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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALOXE3
Full Name:
Epidermis-type lipoxygenase 3
Alias:
Type:
Mass (Da):
80543
Number AA:
711
UniProt ID:
Q9BYJ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
G
P
Y
L
R
A
G
T
L
D
N
I
S
V
T
Site 2
S33
L
V
G
T
C
G
E
S
P
K
Q
R
L
D
R
Site 3
S49
G
R
D
F
A
P
G
S
V
Q
K
Y
K
V
R
Site 4
Y53
A
P
G
S
V
Q
K
Y
K
V
R
C
T
A
E
Site 5
T58
Q
K
Y
K
V
R
C
T
A
E
L
G
E
L
L
Site 6
Y108
C
Y
Q
W
I
E
G
Y
C
T
V
E
L
R
P
Site 7
T110
Q
W
I
E
G
Y
C
T
V
E
L
R
P
G
T
Site 8
T117
T
V
E
L
R
P
G
T
A
R
T
I
C
Q
D
Site 9
S161
P
C
M
V
D
V
N
S
F
Q
E
M
E
S
D
Site 10
S167
N
S
F
Q
E
M
E
S
D
K
K
F
A
L
T
Site 11
T176
K
K
F
A
L
T
K
T
T
T
C
V
D
Q
G
Site 12
S186
C
V
D
Q
G
D
S
S
G
N
R
Y
L
P
G
Site 13
Y190
G
D
S
S
G
N
R
Y
L
P
G
F
P
M
K
Site 14
Y205
I
D
I
P
S
L
M
Y
M
E
P
N
V
R
Y
Site 15
S213
M
E
P
N
V
R
Y
S
A
T
K
T
I
S
L
Site 16
S242
G
L
L
D
R
K
G
S
W
K
K
L
D
D
M
Site 17
Y276
C
E
D
H
F
F
G
Y
Q
Y
L
N
G
V
N
Site 18
Y278
D
H
F
F
G
Y
Q
Y
L
N
G
V
N
P
V
Site 19
S295
H
C
I
S
S
L
P
S
K
L
P
V
T
N
D
Site 20
T312
A
P
L
L
G
Q
D
T
C
L
Q
T
E
L
E
Site 21
S369
V
P
L
A
I
Q
L
S
Q
T
P
G
P
D
S
Site 22
T371
L
A
I
Q
L
S
Q
T
P
G
P
D
S
P
I
Site 23
S376
S
Q
T
P
G
P
D
S
P
I
F
L
P
T
D
Site 24
T382
D
S
P
I
F
L
P
T
D
S
E
W
D
W
L
Site 25
T466
E
G
L
V
D
Q
V
T
S
I
G
R
Q
G
L
Site 26
Y506
G
V
L
A
I
P
N
Y
H
Y
R
D
D
G
L
Site 27
Y508
L
A
I
P
N
Y
H
Y
R
D
D
G
L
K
I
Site 28
Y529
F
V
S
E
I
V
G
Y
Y
Y
P
S
D
A
S
Site 29
Y531
S
E
I
V
G
Y
Y
Y
P
S
D
A
S
V
Q
Site 30
S533
I
V
G
Y
Y
Y
P
S
D
A
S
V
Q
Q
D
Site 31
S536
Y
Y
Y
P
S
D
A
S
V
Q
Q
D
S
E
L
Site 32
S560
Q
A
F
L
G
R
E
S
S
G
F
P
S
R
L
Site 33
S561
A
F
L
G
R
E
S
S
G
F
P
S
R
L
C
Site 34
S565
R
E
S
S
G
F
P
S
R
L
C
T
P
G
E
Site 35
T569
G
F
P
S
R
L
C
T
P
G
E
M
V
K
F
Site 36
S607
A
W
M
P
N
A
P
S
S
M
R
Q
P
P
P
Site 37
S608
W
M
P
N
A
P
S
S
M
R
Q
P
P
P
Q
Site 38
T624
K
G
T
T
T
L
K
T
Y
L
D
T
L
P
E
Site 39
Y625
G
T
T
T
L
K
T
Y
L
D
T
L
P
E
V
Site 40
T628
T
L
K
T
Y
L
D
T
L
P
E
V
N
I
S
Site 41
S646
L
L
L
F
W
L
V
S
Q
E
P
K
D
Q
R
Site 42
Y658
D
Q
R
P
L
G
T
Y
P
D
E
H
F
T
E
Site 43
S671
T
E
E
A
P
R
R
S
I
A
A
F
Q
S
R
Site 44
S683
Q
S
R
L
A
Q
I
S
R
D
I
Q
E
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation