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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARD6B
Full Name:
Partitioning defective 6 homolog beta
Alias:
PAR-6 beta; Par-6 partitioning defective 6 beta; PAR6B; PAR-6B; Partitioning defective 6 beta
Type:
Adhesion
Mass (Da):
41182
Number AA:
372
UniProt ID:
Q9BYG5
International Prot ID:
IPI00019025
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005923
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0007049
GO:0051301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
N
R
S
H
R
H
G
A
G
S
Site 2
S11
S
H
R
H
G
A
G
S
G
C
L
G
T
M
E
Site 3
S21
L
G
T
M
E
V
K
S
K
F
G
A
E
F
R
Site 4
S31
G
A
E
F
R
R
F
S
L
E
R
S
K
P
G
Site 5
S35
R
R
F
S
L
E
R
S
K
P
G
K
F
E
E
Site 6
Y44
P
G
K
F
E
E
F
Y
G
L
L
Q
H
V
H
Site 7
Y78
P
I
N
N
D
D
N
Y
H
K
A
V
S
T
A
Site 8
Y101
Q
K
K
E
E
A
D
Y
S
A
F
G
T
D
T
Site 9
S102
K
K
E
E
A
D
Y
S
A
F
G
T
D
T
L
Site 10
T106
A
D
Y
S
A
F
G
T
D
T
L
I
K
K
K
Site 11
T108
Y
S
A
F
G
T
D
T
L
I
K
K
K
N
V
Site 12
S134
K
K
P
H
I
V
I
S
M
P
Q
D
F
R
P
Site 13
S143
P
Q
D
F
R
P
V
S
S
I
I
D
V
D
I
Site 14
S144
Q
D
F
R
P
V
S
S
I
I
D
V
D
I
L
Site 15
T154
D
V
D
I
L
P
E
T
H
R
R
V
R
L
Y
Site 16
Y161
T
H
R
R
V
R
L
Y
K
Y
G
T
E
K
P
Site 17
Y163
R
R
V
R
L
Y
K
Y
G
T
E
K
P
L
G
Site 18
T165
V
R
L
Y
K
Y
G
T
E
K
P
L
G
F
Y
Site 19
Y172
T
E
K
P
L
G
F
Y
I
R
D
G
S
S
V
Site 20
S177
G
F
Y
I
R
D
G
S
S
V
R
V
T
P
H
Site 21
S178
F
Y
I
R
D
G
S
S
V
R
V
T
P
H
G
Site 22
T182
D
G
S
S
V
R
V
T
P
H
G
L
E
K
V
Site 23
S227
G
I
E
V
S
G
K
S
L
D
Q
V
T
D
M
Site 24
T232
G
K
S
L
D
Q
V
T
D
M
M
I
A
N
S
Site 25
T245
N
S
R
N
L
I
I
T
V
R
P
A
N
Q
R
Site 26
S259
R
N
N
V
V
R
N
S
R
T
S
G
S
S
G
Site 27
T261
N
V
V
R
N
S
R
T
S
G
S
S
G
Q
S
Site 28
S262
V
V
R
N
S
R
T
S
G
S
S
G
Q
S
T
Site 29
S264
R
N
S
R
T
S
G
S
S
G
Q
S
T
D
N
Site 30
S265
N
S
R
T
S
G
S
S
G
Q
S
T
D
N
S
Site 31
S268
T
S
G
S
S
G
Q
S
T
D
N
S
L
L
G
Site 32
T269
S
G
S
S
G
Q
S
T
D
N
S
L
L
G
Y
Site 33
S272
S
G
Q
S
T
D
N
S
L
L
G
Y
P
Q
Q
Site 34
Y276
T
D
N
S
L
L
G
Y
P
Q
Q
I
E
P
S
Site 35
S283
Y
P
Q
Q
I
E
P
S
F
E
P
E
D
E
D
Site 36
S291
F
E
P
E
D
E
D
S
E
E
D
D
I
I
I
Site 37
T314
I
P
K
A
V
P
N
T
E
S
L
E
S
L
T
Site 38
S316
K
A
V
P
N
T
E
S
L
E
S
L
T
Q
I
Site 39
S319
P
N
T
E
S
L
E
S
L
T
Q
I
E
L
S
Site 40
S326
S
L
T
Q
I
E
L
S
F
E
S
G
Q
N
G
Site 41
S337
G
Q
N
G
F
I
P
S
N
E
V
S
L
A
A
Site 42
S349
L
A
A
I
A
S
S
S
N
T
E
F
E
T
H
Site 43
T351
A
I
A
S
S
S
N
T
E
F
E
T
H
A
P
Site 44
T355
S
S
N
T
E
F
E
T
H
A
P
D
Q
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation